| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | VANGUARD GROUP INC | 3,680,345 | 226,009,000 | 6.33% | ||
| 2 | PERCEPTIVE ADVISORS LLC | 3,395,236 | 208,506,000 | 5.84% | ||
| 3 | Point72 Asset Management, L.P. | 3,284,287 | 201,688,000 | 5.65% | ||
| 4 | STATE STREET CORP | 2,959,911 | 181,762,000 | 5.09% | ||
| 5 | Jefferies Group LLC | 2,467,000 | 151,498,000 | 4.24% | Put | |
| 6 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2,415,300 | 148,324,000 | 4.15% | Put | |
| 7 | Jefferies Group LLC | 2,316,214 | 142,239,000 | 3.98% | ||
| 8 | MILLENNIUM MANAGEMENT LLC | 1,955,904 | 120,112,000 | 3.36% | ||
| 9 | BlackRock Fund Advisors | 1,721,948 | 105,745,000 | 2.96% | ||
| 10 | Tourbillon Capital Partners, L.P. | 1,713,000 | 105,195,000 | 2.95% | ||
| 11 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,635,800 | 100,454,000 | 2.81% | Call | |
| 12 | FMR LLC | 1,534,397 | 94,227,000 | 2.64% | ||
| 13 | JENNISON ASSOCIATES LLC | 1,393,788 | 85,593,000 | 2.40% | ||
| 14 | Avoro Capital Advisors LLC | 1,369,909 | 84,126,000 | 2.36% | ||
| 15 | BlackRock Institutional Trust Company, N.A. | 1,107,119 | 67,988,000 | 1.90% | ||
| 16 | BARCLAYS PLC | 1,103,800 | 67,784,000 | 1.90% | Call | |
| 17 | EverPoint Asset Management, LLC | 945,600 | 58,069,000 | 1.63% | Put | |
| 18 | BLACKROCK ADVISORS LLC | 839,928 | 51,580,000 | 1.44% | ||
| 19 | BARCLAYS PLC | 740,000 | 45,443,000 | 1.27% | Put | |
| 20 | CITADEL ADVISORS LLC | 641,739 | 39,409,000 | 1.10% | ||
| 21 | Redmile Group, LLC | 640,400 | 39,327,000 | 1.10% | ||
| 22 | EverPoint Asset Management, LLC | 600,000 | 36,846,000 | 1.03% | ||
| 23 | EverPoint Asset Management, LLC | 600,000 | 36,846,000 | 1.03% | Call | |
| 24 | EAGLE ASSET MANAGEMENT INC | 593,455 | 36,444,000 | 1.02% | ||
| 25 | Hudson Bay Capital Management LP | 539,619 | 33,138,000 | 0.93% | ||
| 26 | SABBY MANAGEMENT, LLC | 536,282 | 32,933,000 | 0.92% | ||
| 27 | PRICE T ROWE ASSOCIATES INC /MD/ | 534,468 | 32,822,000 | 0.92% | ||
| 28 | Invesco Ltd. | 514,823 | 31,615,000 | 0.89% | ||
| 29 | Jefferies Group LLC | 508,800 | 31,245,000 | 0.87% | Call | |
| 30 | NORTHERN TRUST CORP | 507,567 | 31,170,000 | 0.87% | ||
| 31 | QVT Financial LP | 496,434 | 30,486,000 | 0.85% | ||
| 32 | MORGAN STANLEY | 483,547 | 29,695,000 | 0.83% | ||
| 33 | CITADEL ADVISORS LLC | 450,400 | 27,659,000 | 0.77% | Put | |
| 34 | BlackRock Group LTD | 412,069 | 25,304,000 | 0.71% | ||
| 35 | Ghost Tree Capital, LLC | 400,000 | 24,564,000 | 0.69% | Put | |
| 36 | Ghost Tree Capital, LLC | 350,000 | 21,494,000 | 0.60% | Call | |
| 37 | GEODE CAPITAL MANAGEMENT, LLC | 349,518 | 21,462,000 | 0.60% | ||
| 38 | Parallax Volatility Advisers, L.P. | 335,200 | 20,585,000 | 0.58% | Put | |
| 39 | DEUTSCHE BANK AG\ | 332,130 | 20,394,000 | 0.57% | ||
| 40 | NORGES BANK | 341,253 | 20,016,000 | 0.56% | ||
| 41 | LORD, ABBETT & CO. LLC | 302,070 | 18,550,000 | 0.52% | ||
| 42 | Tourbillon Capital Partners, L.P. | 300,000 | 18,424,000 | 0.52% | Call | |
| 43 | UBS Group AG | 296,600 | 18,214,000 | 0.51% | Call | |
| 44 | GOLDMAN SACHS GROUP INC | 282,983 | 17,378,000 | 0.49% | ||
| 45 | WOLVERINE TRADING LP /BD | 279,100 | 17,020,000 | 0.48% | Put | |
| 46 | GOLDMAN SACHS GROUP INC | 273,000 | 16,765,000 | 0.47% | Call | |
| 47 | PointState Capital LP | 270,000 | 16,581,000 | 0.46% | ||
| 48 | EMERALD MUTUAL FUND ADVISERS TRUST | 266,295 | 16,353,000 | 0.46% | ||
| 49 | SPHERA FUNDS MANAGEMENT LTD. | 263,047 | 16,154,000 | 0.45% | ||
| 50 | ORBIMED ADVISORS LLC | 261,800 | 16,077,000 | 0.45% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
