| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | VANGUARD GROUP INC | 3,919,520 | 107,513,000 | 7.83% | ||
| 2 | PERCEPTIVE ADVISORS LLC | 2,769,829 | 75,976,000 | 5.53% | ||
| 3 | STATE STREET CORP | 2,637,785 | 72,352,000 | 5.27% | ||
| 4 | BlackRock Fund Advisors | 2,258,531 | 61,952,000 | 4.51% | ||
| 5 | Carlson Capital, L.P. | 2,202,765 | 60,422,000 | 4.40% | ||
| 6 | SABBY MANAGEMENT, LLC | 2,014,787 | 55,266,000 | 4.02% | ||
| 7 | Tourbillon Capital Partners, L.P. | 1,631,356 | 44,748,000 | 3.26% | ||
| 8 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,556,900 | 42,706,000 | 3.11% | Put | |
| 9 | Tourbillon Capital Partners, L.P. | 1,465,400 | 40,196,000 | 2.93% | Call | |
| 10 | Point72 Asset Management, L.P. | 1,367,599 | 37,513,000 | 2.73% | ||
| 11 | BlackRock Institutional Trust Company, N.A. | 1,306,520 | 35,838,000 | 2.61% | ||
| 12 | Jefferies Group LLC | 1,247,700 | 34,224,000 | 2.49% | Put | |
| 13 | FMR LLC | 1,196,797 | 32,828,000 | 2.39% | ||
| 14 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,043,000 | 28,610,000 | 2.08% | Call | |
| 15 | Avoro Capital Advisors LLC | 1,010,300 | 27,713,000 | 2.02% | ||
| 16 | BLACKROCK ADVISORS LLC | 938,370 | 25,740,000 | 1.87% | ||
| 17 | Jefferies Group LLC | 839,342 | 23,023,000 | 1.68% | ||
| 18 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 726,044 | 19,915,000 | 1.45% | ||
| 19 | BARCLAYS PLC | 671,600 | 18,422,000 | 1.34% | Call | |
| 20 | Artal Group S.A. | 600,000 | 16,458,000 | 1.20% | Call | |
| 21 | EAGLE ASSET MANAGEMENT INC | 592,172 | 16,243,000 | 1.18% | ||
| 22 | NORTHERN TRUST CORP | 580,523 | 15,924,000 | 1.16% | ||
| 23 | JENNISON ASSOCIATES LLC | 563,333 | 15,452,000 | 1.13% | ||
| 24 | EMERALD ADVISERS, LLC | 548,571 | 15,047,000 | 1.10% | ||
| 25 | Tekla Capital Management LLC | 466,300 | 12,791,000 | 0.93% | ||
| 26 | BlackRock Group LTD | 460,568 | 12,632,000 | 0.92% | ||
| 27 | Invesco Ltd. | 456,598 | 12,524,000 | 0.91% | ||
| 28 | CITADEL ADVISORS LLC | 452,960 | 12,425,000 | 0.90% | ||
| 29 | NORGES BANK | 407,604 | 11,181,000 | 0.81% | ||
| 30 | EMERALD MUTUAL FUND ADVISERS TRUST | 402,525 | 11,041,000 | 0.80% | ||
| 31 | Parallax Volatility Advisers, L.P. | 400,000 | 10,972,000 | 0.80% | Put | |
| 32 | SPHERA FUNDS MANAGEMENT LTD. | 398,047 | 10,918,000 | 0.79% | ||
| 33 | GEODE CAPITAL MANAGEMENT, LLC | 391,444 | 10,737,000 | 0.78% | ||
| 34 | PRICE T ROWE ASSOCIATES INC /MD/ | 381,173 | 10,456,000 | 0.76% | ||
| 35 | EverPoint Asset Management, LLC | 371,554 | 10,192,000 | 0.74% | ||
| 36 | CADIAN CAPITAL MANAGEMENT, LP | 348,954 | 9,572,000 | 0.70% | ||
| 37 | MILLENNIUM MANAGEMENT LLC | 341,497 | 9,367,000 | 0.68% | ||
| 38 | Elk Creek Partners, LLC | 316,463 | 8,681,000 | 0.63% | ||
| 39 | DEUTSCHE BANK AG\ | 314,364 | 8,622,000 | 0.63% | ||
| 40 | BALYASNY ASSET MANAGEMENT L.P. | 300,000 | 8,229,000 | 0.60% | Call | |
| 41 | NOMURA HOLDINGS INC | 273,000 | 7,577,000 | 0.55% | Call | |
| 42 | Jefferies Group LLC | 265,400 | 7,280,000 | 0.53% | Call | |
| 43 | TWO SIGMA INVESTMENTS, LP | 263,229 | 7,220,000 | 0.53% | ||
| 44 | Bank of New York Mellon Corp | 246,001 | 6,747,000 | 0.49% | ||
| 45 | GOLDMAN SACHS GROUP INC | 238,363 | 6,539,000 | 0.48% | ||
| 46 | BlackRock Investment Management, LLC | 228,628 | 6,271,000 | 0.46% | ||
| 47 | TEACHERS ADVISORS, LLC | 222,786 | 6,111,000 | 0.44% | ||
| 48 | TIAA CREF INVESTMENT MANAGEMENT LLC | 213,246 | 5,849,000 | 0.43% | ||
| 49 | QVT Financial LP | 212,776 | 5,836,000 | 0.42% | ||
| 50 | MORGAN STANLEY | 209,284 | 5,741,000 | 0.42% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
