| 1 |
NEA Management Company, LLC |
10,362,694 |
5,596,000 |
34.97% |
|
|
| 2 |
PERCEPTIVE ADVISORS LLC |
3,108,808 |
1,678,000 |
10.49% |
|
|
| 3 |
RENAISSANCE TECHNOLOGIES LLC |
2,743,900 |
1,482,000 |
9.26% |
|
|
| 4 |
New Leaf Venture Partners, L.L.C. |
2,590,673 |
1,399,000 |
8.74% |
|
|
| 5 |
VANGUARD GROUP INC |
2,459,746 |
1,329,000 |
8.30% |
|
|
| 6 |
BlackRock Institutional Trust Company, N.A. |
1,945,975 |
1,051,000 |
6.57% |
|
|
| 7 |
Sarissa Capital Management LP |
1,700,000 |
917,000 |
5.73% |
|
|
| 8 |
Cormorant Asset Management, LP |
1,087,715 |
587,000 |
3.67% |
|
|
| 9 |
683 Capital Management, LLC |
1,000,000 |
540,000 |
3.37% |
|
|
| 10 |
Deer VI & Co. LLC |
675,242 |
365,000 |
2.28% |
|
|
| 11 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
460,964 |
249,000 |
1.56% |
|
|
| 12 |
GEODE CAPITAL MANAGEMENT, LLC |
303,283 |
163,000 |
1.02% |
|
|
| 13 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
289,529 |
156,000 |
0.97% |
|
|
| 14 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
234,698 |
127,000 |
0.79% |
|
|
| 15 |
NORTHERN TRUST CORP |
105,844 |
57,000 |
0.36% |
|
|
| 16 |
Spark Investment Management LLC |
95,800 |
51,000 |
0.32% |
|
|
| 17 |
Cannell & Co. |
89,375 |
48,000 |
0.30% |
|
|
| 18 |
TUDOR INVESTMENT CORP ET AL |
83,869 |
45,000 |
0.28% |
|
|
| 19 |
Bank of New York Mellon Corp |
61,160 |
33,000 |
0.21% |
|
|
| 20 |
Evercore Wealth Management, LLC |
38,881 |
21,000 |
0.13% |
|
|
| 21 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
33,400 |
18,000 |
0.11% |
|
|
| 22 |
STATE STREET CORP |
25,375 |
14,000 |
0.09% |
|
|
| 23 |
GUGGENHEIM CAPITAL LLC |
18,454 |
10,000 |
0.06% |
|
|
| 24 |
Connor, Clark & Lunn Investment Management Ltd. |
18,500 |
10,000 |
0.06% |
|
|
| 25 |
BlackRock Fund Advisors |
16,272 |
9,000 |
0.06% |
|
|
| 26 |
TWO SIGMA SECURITIES, LLC |
14,738 |
8,000 |
0.05% |
|
|
| 27 |
Virtu KCG Holdings LLC |
13,537 |
7,000 |
0.04% |
|
|
| 28 |
BLACKROCK ADVISORS LLC |
13,305 |
7,000 |
0.04% |
|
|
| 29 |
CITADEL ADVISORS LLC |
10,700 |
6,000 |
0.04% |
Call |
|
| 30 |
Edge Wealth Management LLC |
10,000 |
5,000 |
0.03% |
|
|
| 31 |
ELGETHUN CAPITAL MANAGEMENT |
10,000 |
5,000 |
0.03% |
|
|
| 32 |
BANK OF AMERICA CORP /DE/ |
5,095 |
3,000 |
0.02% |
|
|
| 33 |
Creative Planning |
3,000 |
2,000 |
0.01% |
|
|
| 34 |
MSI Financial Services Inc |
1,000 |
1,000 |
0.01% |
|
|
| 35 |
CUTLER GROUP LLC / CA |
2,963 |
1,000 |
0.01% |
|
|
| 36 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
1,190 |
1,000 |
0.01% |
|
|
| 37 |
Tower Research Capital LLC (TRC) |
1,076 |
1,000 |
0.01% |
|
|
| 38 |
CT Financial Advisors LLC |
800 |
432 |
0.00% |
|
|
| 39 |
GLOBAL RETIREMENT PARTNERS, LLC |
360 |
0 |
0.00% |
|
|
| 40 |
UBS Group AG |
225 |
0 |
0.00% |
|
|
| 41 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
250 |
0 |
0.00% |
|
|
| 42 |
BlackRock Finance, Inc. |
669 |
0 |
0.00% |
|
|
| 43 |
ADVISOR GROUP, INC. |
467 |
0 |
0.00% |
|
|
| 44 |
WELLS FARGO & COMPANY/MN |
800 |
0 |
0.00% |
|
|
| 45 |
MORGAN STANLEY |
500 |
0 |
0.00% |
|
|
