| 1 |
BVF INC/IL |
10,772,306 |
8,187,000 |
73.08% |
|
|
| 2 |
BlackRock Institutional Trust Company, N.A. |
1,520,606 |
1,156,000 |
10.32% |
|
|
| 3 |
VANGUARD GROUP INC |
896,193 |
681,000 |
6.08% |
|
|
| 4 |
GEODE CAPITAL MANAGEMENT, LLC |
350,319 |
266,000 |
2.37% |
|
|
| 5 |
BlackRock Fund Advisors |
163,756 |
124,000 |
1.11% |
|
|
| 6 |
D. E. Shaw & Co., Inc. |
136,786 |
104,000 |
0.93% |
|
|
| 7 |
First Horizon Advisors, Inc. |
128,000 |
97,000 |
0.87% |
|
|
| 8 |
MORGAN STANLEY |
71,071 |
54,000 |
0.48% |
|
|
| 9 |
NORTHERN TRUST CORP |
69,408 |
53,000 |
0.47% |
|
|
| 10 |
Spark Investment Management LLC |
61,100 |
46,000 |
0.41% |
|
|
| 11 |
GROUP ONE TRADING LLC |
43,247 |
33,000 |
0.29% |
|
|
| 12 |
Bank of New York Mellon Corp |
39,379 |
30,000 |
0.27% |
|
|
| 13 |
NOMURA HOLDINGS INC |
33,916 |
29,000 |
0.26% |
|
|
| 14 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
37,700 |
29,000 |
0.26% |
|
|
| 15 |
STIFEL FINANCIAL CORP |
36,900 |
28,000 |
0.25% |
|
|
| 16 |
TUDOR INVESTMENT CORP ET AL |
34,033 |
26,000 |
0.23% |
|
|
| 17 |
J.P. Turner & Co Capital Mnagement, LLC |
31,900 |
25,000 |
0.22% |
|
|
| 18 |
FCG ADVISORS, LLC |
23,478 |
18,000 |
0.16% |
|
|
| 19 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
20,400 |
16,000 |
0.14% |
Put |
|
| 20 |
Cannell & Co. |
20,000 |
15,000 |
0.13% |
|
|
| 21 |
STATE STREET CORP |
20,538 |
15,000 |
0.13% |
|
|
| 22 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
19,323 |
15,000 |
0.13% |
|
|
| 23 |
LPL Financial LLC |
18,000 |
15,000 |
0.13% |
|
|
| 24 |
GOLDMAN SACHS GROUP INC |
19,045 |
14,000 |
0.12% |
|
|
| 25 |
BLACKROCK ADVISORS LLC |
17,845 |
14,000 |
0.12% |
|
|
| 26 |
DELTA ASSET MANAGEMENT LLC/TN |
18,800 |
14,000 |
0.12% |
|
|
| 27 |
HIGHLAND CAPITAL MANAGEMENT, LLC |
16,734 |
13,000 |
0.12% |
|
|
| 28 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
15,900 |
13,000 |
0.12% |
|
|
| 29 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
16,000 |
12,000 |
0.11% |
Call |
|
| 30 |
CITADEL ADVISORS LLC |
13,309 |
10,000 |
0.09% |
|
|
| 31 |
BANK OF AMERICA CORP /DE/ |
12,500 |
10,000 |
0.09% |
|
|
| 32 |
BlackRock Investment Management, LLC |
10,904 |
8,000 |
0.07% |
|
|
| 33 |
WELLS FARGO & COMPANY/MN |
10,000 |
8,000 |
0.07% |
|
|
| 34 |
THOMPSON DAVIS & CO., INC. |
8,000 |
6,000 |
0.05% |
|
|
| 35 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
7,706 |
6,000 |
0.05% |
|
|
| 36 |
UBS Group AG |
6,300 |
5,000 |
0.04% |
|
|
| 37 |
CITIGROUP INC |
5,000 |
4,000 |
0.04% |
|
|
| 38 |
SIMPLEX TRADING, LLC |
2,985 |
2,000 |
0.02% |
|
|
| 39 |
AMERICAN INTERNATIONAL GROUP, INC. |
1,700 |
1,000 |
0.01% |
|
|
| 40 |
Creative Planning |
1,000 |
1,000 |
0.01% |
|
|
| 41 |
BARCLAYS PLC |
8,600 |
0 |
0.00% |
Call |
|
| 42 |
MSI Financial Services Inc |
201 |
0 |
0.00% |
|
|
| 43 |
TD Capital Management LLC |
100 |
0 |
0.00% |
|
|
| 44 |
ROYAL BANK OF CANADA |
130 |
0 |
0.00% |
|
|
