| # | % | |||||
|---|---|---|---|---|---|---|
| 101 | First Light Asset Management, LLC | 992,867 | 3,227,000 | 1.84% | ||
| 102 | NORTHERN TRUST CORP | 1,048,928 | 3,409,000 | 1.94% | ||
| 103 | FMR LLC | 1,132,648 | 3,681,000 | 2.10% | ||
| 104 | Opaleye Management Inc. | 1,200,000 | 3,900,000 | 2.22% | ||
| 105 | NEXTHERA CAPITAL LP | 1,263,276 | 4,106,000 | 2.34% | ||
| 106 | MILLENNIUM MANAGEMENT LLC | 1,277,794 | 4,153,000 | 2.36% | ||
| 107 | STATE STREET CORP | 1,431,793 | 4,651,000 | 2.65% | ||
| 108 | Tourbillon Capital Partners, L.P. | 1,500,000 | 4,876,000 | 2.78% | Call | |
| 109 | BALYASNY ASSET MANAGEMENT L.P. | 1,569,885 | 5,102,000 | 2.91% | ||
| 110 | J. Goldman & Co LP | 1,696,699 | 5,514,000 | 3.14% | ||
| 111 | Ghost Tree Capital, LLC | 2,000,000 | 6,500,000 | 3.70% | ||
| 112 | Tourbillon Capital Partners, L.P. | 2,400,000 | 7,800,000 | 4.44% | ||
| 113 | BlackRock Institutional Trust Company, N.A. | 2,792,320 | 9,075,000 | 5.17% | ||
| 114 | BlackRock Fund Advisors | 3,743,062 | 12,165,000 | 6.93% | ||
| 115 | VANGUARD GROUP INC | 3,752,828 | 12,197,000 | 6.95% | ||
| 116 | ORBIMED ADVISORS LLC | 3,802,000 | 12,357,000 | 7.04% | ||
| 117 | ACUTA CAPITAL PARTNERS, LLC | 3,850,000 | 12,513,000 | 7.13% | ||
| 118 | Avoro Capital Advisors LLC | 7,344,177 | 23,869,000 | 13.59% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
