| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SABBY MANAGEMENT, LLC | 2,680,000 | 182,240,000 | 59.65% | PRN | |
| 2 | FMR LLC | 11,166,048 | 27,915,000 | 9.14% | ||
| 3 | ACUTA CAPITAL PARTNERS, LLC | 5,526,172 | 13,815,000 | 4.52% | ||
| 4 | ORBIMED ADVISORS LLC | 3,802,000 | 9,505,000 | 3.11% | ||
| 5 | BlackRock Fund Advisors | 3,749,748 | 9,374,000 | 3.07% | ||
| 6 | VANGUARD GROUP INC | 3,607,879 | 9,020,000 | 2.95% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 2,751,297 | 6,878,000 | 2.25% | ||
| 8 | BALYASNY ASSET MANAGEMENT L.P. | 2,084,312 | 5,211,000 | 1.71% | ||
| 9 | First Light Asset Management, LLC | 1,543,542 | 3,859,000 | 1.26% | ||
| 10 | STATE STREET CORP | 1,442,360 | 3,609,000 | 1.18% | ||
| 11 | PERCEPTIVE ADVISORS LLC | 1,420,000 | 3,550,000 | 1.16% | ||
| 12 | Opaleye Management Inc. | 1,325,000 | 3,313,000 | 1.08% | ||
| 13 | NORTHERN TRUST CORP | 1,117,526 | 2,793,000 | 0.91% | ||
| 14 | Avoro Capital Advisors LLC | 1,050,457 | 2,626,000 | 0.86% | ||
| 15 | PANAGORA ASSET MANAGEMENT INC | 874,754 | 2,187,000 | 0.72% | ||
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 570,322 | 1,425,000 | 0.47% | ||
| 17 | TIAA CREF INVESTMENT MANAGEMENT LLC | 439,656 | 1,099,000 | 0.36% | ||
| 18 | Bank of New York Mellon Corp | 421,401 | 1,053,000 | 0.34% | ||
| 19 | MILLENNIUM MANAGEMENT LLC | 350,697 | 877,000 | 0.29% | ||
| 20 | BlackRock Investment Management, LLC | 345,085 | 863,000 | 0.28% | ||
| 21 | BAILARD, INC. | 315,000 | 788,000 | 0.26% | ||
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 296,100 | 740,000 | 0.24% | Call | |
| 23 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 288,900 | 722,000 | 0.24% | ||
| 24 | BARCLAYS PLC | 310,916 | 622,000 | 0.20% | ||
| 25 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 206,239 | 516,000 | 0.17% | ||
| 26 | IFP ADVISORS, INC | 198,517 | 496,000 | 0.16% | ||
| 27 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 197,048 | 493,000 | 0.16% | ||
| 28 | WELLS FARGO & COMPANY/MN | 183,619 | 460,000 | 0.15% | ||
| 29 | TEACHERS ADVISORS, LLC | 176,467 | 441,000 | 0.14% | ||
| 30 | SVB WEALTH LLC | 170,000 | 425,000 | 0.14% | ||
| 31 | A.R.T. Advisors, LLC | 161,193 | 402,000 | 0.13% | ||
| 32 | BALYASNY ASSET MANAGEMENT L.P. | 145,800 | 365,000 | 0.12% | Call | |
| 33 | Connor, Clark & Lunn Investment Management Ltd. | 144,500 | 361,000 | 0.12% | ||
| 34 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 143,500 | 359,000 | 0.12% | Put | |
| 35 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 140,800 | 352,000 | 0.12% | ||
| 36 | Swiss National Bank | 141,550 | 341,000 | 0.11% | ||
| 37 | ALLIANCEBERNSTEIN L.P. | 113,298 | 283,000 | 0.09% | ||
| 38 | CITIGROUP INC | 105,837 | 265,000 | 0.09% | ||
| 39 | RHUMBLINE ADVISERS | 102,635 | 257,000 | 0.08% | ||
| 40 | Raymond James Financial Services Advisors, Inc. | 98,102 | 245,000 | 0.08% | ||
| 41 | CREDIT SUISSE AG/ | 96,655 | 241,000 | 0.08% | ||
| 42 | CSS LLC/IL | 96,000 | 239,000 | 0.08% | Put | |
| 43 | STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM | 93,107 | 233,000 | 0.08% | ||
| 44 | NEW YORK STATE COMMON RETIREMENT FUND | 87,900 | 220,000 | 0.07% | ||
| 45 | VIRTUS ETF ADVISERS LLC | 87,062 | 218,000 | 0.07% | ||
| 46 | ProShare Advisors LLC | 81,936 | 205,000 | 0.07% | ||
| 47 | Weiss Multi-Strategy Advisers LLC | 80,000 | 200,000 | 0.07% | ||
| 48 | METROPOLITAN LIFE INSURANCE CO/NY | 74,458 | 186,000 | 0.06% | ||
| 49 | PURA VIDA INVESTMENTS, LLC | 72,500 | 181,000 | 0.06% | ||
| 50 | GOLDMAN SACHS GROUP INC | 69,986 | 175,000 | 0.06% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
