| # | % | |||||
|---|---|---|---|---|---|---|
| 101 | Palo Alto Investors LP | 905,259 | 35,993,000 | 5.10% | ||
| 102 | WADDELL & REED FINANCIAL INC | 945,120 | 37,578,000 | 5.32% | ||
| 103 | PFM Health Sciences, LP | 1,003,492 | 39,899,000 | 5.65% | ||
| 104 | JENNISON ASSOCIATES LLC | 1,527,773 | 60,744,000 | 8.61% | ||
| 105 | FMR LLC | 3,279,635 | 130,399,000 | 18.48% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.