| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAUPOST GROUP LLC/MA | 5,359,632 | 141,548,000 | 27.74% | ||
| 2 | FMR LLC | 2,085,790 | 55,086,000 | 10.79% | ||
| 3 | Redmile Group, LLC | 1,534,962 | 40,538,000 | 7.94% | ||
| 4 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,235,435 | 32,628,000 | 6.39% | ||
| 5 | EAGLE ASSET MANAGEMENT INC | 853,400 | 22,538,000 | 4.42% | ||
| 6 | BlackRock Fund Advisors | 748,592 | 19,770,000 | 3.87% | ||
| 7 | ArrowMark Colorado Holdings LLC | 736,520 | 19,451,000 | 3.81% | ||
| 8 | Visium Asset Management, LP | 722,626 | 19,085,000 | 3.74% | ||
| 9 | BRIDGER MANAGEMENT, LLC | 706,848 | 18,668,000 | 3.66% | ||
| 10 | STATE STREET CORP | 601,687 | 15,889,000 | 3.11% | ||
| 11 | VANGUARD GROUP INC | 583,135 | 15,401,000 | 3.02% | ||
| 12 | Neuberger Berman Group LLC | 493,915 | 13,044,000 | 2.56% | ||
| 13 | RTW INVESTMENTS, LP | 425,852 | 11,247,000 | 2.20% | ||
| 14 | 12 West Capital Management LP | 393,700 | 10,398,000 | 2.04% | ||
| 15 | BlackRock Institutional Trust Company, N.A. | 390,388 | 10,310,000 | 2.02% | ||
| 16 | NORTHERN TRUST CORP | 187,073 | 4,940,000 | 0.97% | ||
| 17 | TIVERTON ASSET MANAGEMENT LLC | 185,113 | 4,889,000 | 0.96% | ||
| 18 | Cormorant Asset Management, LP | 150,000 | 3,962,000 | 0.78% | ||
| 19 | GEODE CAPITAL MANAGEMENT, LLC | 132,254 | 3,492,000 | 0.68% | ||
| 20 | TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY | 126,400 | 3,338,000 | 0.65% | ||
| 21 | MORGAN STANLEY | 125,960 | 3,326,000 | 0.65% | ||
| 22 | Invesco Ltd. | 110,173 | 2,910,000 | 0.57% | ||
| 23 | OXFORD ASSET MANAGEMENT LLP | 100,632 | 2,538,000 | 0.50% | ||
| 24 | ACUTA CAPITAL PARTNERS, LLC | 95,000 | 2,509,000 | 0.49% | ||
| 25 | TEACHERS ADVISORS, LLC | 90,153 | 2,381,000 | 0.47% | ||
| 26 | Bank of New York Mellon Corp | 87,414 | 2,308,000 | 0.45% | ||
| 27 | BANK OF AMERICA CORP /DE/ | 75,985 | 2,007,000 | 0.39% | ||
| 28 | Cupps Capital Management, LLC | 74,727 | 1,973,000 | 0.39% | ||
| 29 | TIAA CREF INVESTMENT MANAGEMENT LLC | 73,782 | 1,949,000 | 0.38% | ||
| 30 | JPMORGAN CHASE & CO | 60,700 | 1,603,000 | 0.31% | ||
| 31 | BlackRock Investment Management, LLC | 55,993 | 1,479,000 | 0.29% | ||
| 32 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 52,121 | 1,377,000 | 0.27% | ||
| 33 | NORGES BANK | 40,010 | 1,057,000 | 0.21% | ||
| 34 | ALPS ADVISORS INC | 37,718 | 996,000 | 0.20% | ||
| 35 | Parallax Volatility Advisers, L.P. | 37,000 | 977,000 | 0.19% | Put | |
| 36 | A.R.T. Advisors, LLC | 35,611 | 940,000 | 0.18% | ||
| 37 | UBS Group AG | 35,046 | 925,000 | 0.18% | ||
| 38 | WELLS FARGO & COMPANY/MN | 31,501 | 832,000 | 0.16% | ||
| 39 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 31,200 | 824,000 | 0.16% | ||
| 40 | CREDIT SUISSE AG/ | 25,930 | 685,000 | 0.13% | ||
| 41 | ALLIANCEBERNSTEIN L.P. | 21,440 | 674,000 | 0.13% | ||
| 42 | ProShare Advisors LLC | 25,478 | 673,000 | 0.13% | ||
| 43 | CASDIN CAPITAL, LLC | 25,000 | 660,000 | 0.13% | ||
| 44 | Vident Investment Advisory, LLC | 22,497 | 594,000 | 0.12% | ||
| 45 | Swiss National Bank | 20,900 | 552,000 | 0.11% | ||
| 46 | TUDOR INVESTMENT CORP ET AL | 19,100 | 504,000 | 0.10% | ||
| 47 | NEW YORK STATE COMMON RETIREMENT FUND | 18,100 | 478,000 | 0.09% | ||
| 48 | RHUMBLINE ADVISERS | 17,370 | 459,000 | 0.09% | ||
| 49 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 14,300 | 377,000 | 0.07% | Put | |
| 50 | LANDSCAPE CAPITAL MANAGEMENT, L.L.C. | 12,715 | 336,000 | 0.07% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
