| 1 |
ADAGE CAPITAL PARTNERS GP, L.L.C. |
3,135,069 |
11,631,000 |
33.32% |
|
|
| 2 |
MORGENTHALER MANAGEMENT PARTNERS IX, LLC |
2,161,915 |
8,280,000 |
23.72% |
|
|
| 3 |
FMR LLC |
2,002,278 |
7,428,000 |
21.28% |
|
|
| 4 |
VANGUARD GROUP INC |
430,622 |
1,598,000 |
4.58% |
|
|
| 5 |
BlackRock Institutional Trust Company, N.A. |
230,825 |
856,000 |
2.45% |
|
|
| 6 |
First Eagle Investment Management, LLC |
205,369 |
762,000 |
2.18% |
|
|
| 7 |
Candriam S.C.A. |
190,199 |
706,000 |
2.02% |
|
|
| 8 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
157,850 |
586,000 |
1.68% |
|
|
| 9 |
BVF INC/IL |
121,400 |
450,000 |
1.29% |
|
|
| 10 |
MILLENNIUM MANAGEMENT LLC |
97,141 |
360,000 |
1.03% |
|
|
| 11 |
GEODE CAPITAL MANAGEMENT, LLC |
55,351 |
205,000 |
0.59% |
|
|
| 12 |
WELLS FARGO & COMPANY/MN |
53,405 |
198,000 |
0.57% |
|
|
| 13 |
CREDIT SUISSE AG/ |
53,183 |
198,000 |
0.57% |
|
|
| 14 |
GSA CAPITAL PARTNERS LLP |
43,800 |
162,000 |
0.46% |
|
|
| 15 |
Paloma Partners Management Co |
40,338 |
150,000 |
0.43% |
|
|
| 16 |
D. E. Shaw & Co., Inc. |
37,249 |
138,000 |
0.40% |
|
|
| 17 |
BlackRock Fund Advisors |
35,346 |
131,000 |
0.38% |
|
|
| 18 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
27,090 |
101,000 |
0.29% |
|
|
| 19 |
GOLDMAN SACHS GROUP INC |
24,458 |
91,000 |
0.26% |
|
|
| 20 |
AQR CAPITAL MANAGEMENT LLC |
24,395 |
90,000 |
0.26% |
|
|
| 21 |
DEUTSCHE BANK AG\ |
20,581 |
76,000 |
0.22% |
|
|
| 22 |
Bank of New York Mellon Corp |
19,879 |
74,000 |
0.21% |
|
|
| 23 |
NORTHERN TRUST CORP |
16,498 |
61,000 |
0.17% |
|
|
| 24 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
16,565 |
61,000 |
0.17% |
|
|
| 25 |
Alpine Global Management, LLC |
15,495 |
57,000 |
0.16% |
|
|
| 26 |
LMR Partners LLP |
14,573 |
54,000 |
0.15% |
|
|
| 27 |
A.R.T. Advisors, LLC |
14,451 |
53,000 |
0.15% |
|
|
| 28 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
14,100 |
52,000 |
0.15% |
|
|
| 29 |
HOWLAND CAPITAL MANAGEMENT LLC |
12,000 |
45,000 |
0.13% |
|
|
| 30 |
WEDBUSH SECURITIES INC |
11,500 |
43,000 |
0.12% |
|
|
| 31 |
Connor, Clark & Lunn Investment Management Ltd. |
10,500 |
39,000 |
0.11% |
|
|
| 32 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
10,000 |
37,000 |
0.11% |
Call |
|
| 33 |
ADVANTAGE INVESTMENT MANAGEMENT, LLC |
7,300 |
27,000 |
0.08% |
|
|
| 34 |
Amici Capital, LLC |
6,360 |
24,000 |
0.07% |
|
|
| 35 |
MORGAN STANLEY |
5,621 |
21,000 |
0.06% |
|
|
| 36 |
BANK OF AMERICA CORP /DE/ |
3,598 |
13,000 |
0.04% |
|
|
| 37 |
UBS Group AG |
3,201 |
12,000 |
0.03% |
|
|
| 38 |
BLACKROCK ADVISORS LLC |
2,540 |
9,000 |
0.03% |
|
|
| 39 |
BlackRock Investment Management, LLC |
2,467 |
9,000 |
0.03% |
|
|
| 40 |
BARCLAYS PLC |
1,443 |
5,000 |
0.01% |
|
|
| 41 |
JPMORGAN CHASE & CO |
1,061 |
4,000 |
0.01% |
|
|
| 42 |
Tower Research Capital LLC (TRC) |
1,009 |
4,000 |
0.01% |
|
|
| 43 |
BANK OF MONTREAL /CAN/ |
263 |
1,000 |
0.00% |
|
|
| 44 |
PNC FINANCIAL SERVICES GROUP, INC. |
5 |
0 |
0.00% |
|
|
| 45 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
108 |
0 |
0.00% |
|
|
