| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | UNITED THERAPEUTICS | 1,429,928 | 246,570,000 | 12.19% | ||
| 2 | BIOMARIN | 1,649,792 | 205,597,000 | 10.16% | ||
| 3 | Anacor Pharmaceuticals Inc | 3,259,045 | 188,536,000 | 9.32% | ||
| 4 | ABIOMED INC | 2,473,624 | 177,062,000 | 8.75% | ||
| 5 | CLOVIS ONCOLOGY INC | 2,121,857 | 157,505,000 | 7.79% | ||
| 6 | AMAG PHARMACEUTICALS INC COM | 2,187,041 | 119,544,000 | 5.91% | ||
| 7 | THORATEC LABS CORP | 2,538,203 | 106,325,000 | 5.26% | ||
| 8 | INSMED INC COM PAR .01 | 4,649,448 | 96,709,000 | 4.78% | ||
| 9 | ENDO INTL | 860,204 | 77,160,000 | 3.81% | ||
| 10 | KYTHERA BIOPHARMACEUTICALS I | 1,382,722 | 69,344,000 | 3.43% | ||
| 11 | WRIGHT MEDICAL GROUP NV | 2,049,251 | 52,871,000 | 2.61% | ||
| 12 | SEQUENOM INC | 9,977,642 | 39,412,000 | 1.95% | ||
| 13 | VANDA PHARMACEUTICALS INC COM | 3,803,408 | 35,372,000 | 1.75% | ||
| 14 | KARYOPHARM THERAPEUTICS INC COM | 951,032 | 29,111,000 | 1.44% | ||
| 15 | CELGENE CORP | 249,400 | 28,751,000 | 1.42% | ||
| 16 | GILEAD SCIENCES INC | 291,000 | 28,556,000 | 1.41% | ||
| 17 | CELLADON CORP | 1,445,100 | 27,370,000 | 1.35% | ||
| 18 | LIVANOVA PLC | 412,000 | 26,747,000 | 1.32% | ||
| 19 | PROTHENA CORP PLC | 695,918 | 26,542,000 | 1.31% | ||
| 20 | SHIRE PLC | 95,000 | 22,733,000 | 1.12% | ||
| 21 | MEDIVATION INC | 171,700 | 22,161,000 | 1.10% | ||
| 22 | Momenta Pharmaceuticals Inc | 1,455,176 | 22,119,000 | 1.09% | ||
| 23 | Heartware International, Inc. | 243,868 | 21,404,000 | 1.06% | ||
| 24 | AMICUS THERAPEUTICS INC | 1,956,376 | 21,285,000 | 1.05% | ||
| 25 | STAAR SURGICAL CO | 2,642,922 | 19,637,000 | 0.97% | ||
| 26 | RIGEL PHARMACEUTICAL INC | 5,176,319 | 18,479,000 | 0.91% | ||
| 27 | ARIAD PHARMACEUTICALS INC | 2,231,717 | 18,389,000 | 0.91% | ||
| 28 | ZELTIQ AESTHETICS INCORPORATED | 568,436 | 17,525,000 | 0.87% | ||
| 29 | Intuitive Surgical Inc | 32,350 | 16,338,000 | 0.81% | ||
| 30 | ALIGN TECHNOLOGY INC | 282,057 | 15,170,000 | 0.75% | ||
| 31 | Orexigen Therapeutics, Inc. | 1,931,324 | 15,122,000 | 0.75% | ||
| 32 | ALIMERA SCIENCES INC | 3,013,793 | 15,099,000 | 0.75% | ||
| 33 | EXACT SCIENCES CORP | 392,676 | 8,647,000 | 0.43% | ||
| 34 | ACELRX PHARMACEUTICALS INC | 2,135,739 | 8,244,000 | 0.41% | ||
| 35 | HISTOGENICS CORP | 454,545 | 4,541,000 | 0.22% | ||
| 36 | IDERA PHARMACEUTICALS INC | 1,170,248 | 4,342,000 | 0.21% | ||
| 37 | XOMA CORP DEL | 794,500 | 2,892,000 | 0.14% | ||
| 38 | INTREXON CORP | 47,100 | 2,137,000 | 0.11% | ||
| 39 | BIOSPECIFICS TECHNOLOGIES CORP COM | 50,436 | 1,975,000 | 0.10% | ||
| 40 | Sunesis Pharmaceuticals I | 603,400 | 1,478,000 | 0.07% | ||
| 41 | QLT INC | 315,906 | 1,235,000 | 0.06% | ||
| 42 | SALIX PHARMACEUTICALS INC | 5,300 | 916,000 | 0.05% | ||
| 43 | CYTOKINETICS INC | 123,686 | 839,000 | 0.04% | ||
| 44 | MALLINCKRODT PUB LTD CO SHS | 3,588 | 454,000 | 0.02% | ||
| 45 | ALCOBRA LTD | 73,188 | 412,000 | 0.02% | ||
| 46 | SOPHIRIS BIO INC | 191,600 | 111,000 | 0.01% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001306923-15-000016, filed 2015.05.15).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
