| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | UNITED THERAPEUTICS | 1,439,928 | 250,475,000 | 11.14% | ||
| 2 | Anacor Pharmaceuticals Inc | 3,103,027 | 240,267,000 | 10.68% | ||
| 3 | BIOMARIN | 1,660,092 | 227,067,000 | 10.10% | ||
| 4 | CLOVIS ONCOLOGY INC | 2,401,117 | 211,010,000 | 9.38% | ||
| 5 | ABIOMED INC | 2,742,305 | 180,252,000 | 8.01% | ||
| 6 | AMAG PHARMACEUTICALS INC COM | 2,192,141 | 151,389,000 | 6.73% | ||
| 7 | INSMED INC COM PAR .01 | 4,733,601 | 115,595,000 | 5.14% | ||
| 8 | THORATEC LABS CORP | 2,560,303 | 114,113,000 | 5.07% | ||
| 9 | KYTHERA BIOPHARMACEUTICALS I | 1,290,292 | 97,172,000 | 4.32% | ||
| 10 | ENDO INTL | 864,604 | 68,866,000 | 3.06% | ||
| 11 | WRIGHT MEDICAL GROUP NV | 2,056,251 | 53,997,000 | 2.40% | ||
| 12 | VANDA PHARMACEUTICALS INC COM | 3,897,408 | 49,458,000 | 2.20% | ||
| 13 | KARYOPHARM THERAPEUTICS INC COM | 1,731,530 | 47,115,000 | 2.09% | ||
| 14 | PROTHENA CORP PLC | 695,918 | 36,654,000 | 1.63% | ||
| 15 | GILEAD SCIENCES INC | 299,500 | 35,065,000 | 1.56% | ||
| 16 | Momenta Pharmaceuticals Inc | 1,455,176 | 33,193,000 | 1.48% | ||
| 17 | SEQUENOM INC | 10,023,842 | 30,472,000 | 1.35% | ||
| 18 | CELGENE CORP | 262,200 | 30,346,000 | 1.35% | ||
| 19 | AMICUS THERAPEUTICS INC | 1,974,376 | 27,937,000 | 1.24% | ||
| 20 | STAAR SURGICAL CO | 2,642,922 | 25,531,000 | 1.14% | ||
| 21 | LIVANOVA PLC | 412,000 | 24,498,000 | 1.09% | ||
| 22 | SHIRE PLC | 98,300 | 23,738,000 | 1.06% | ||
| 23 | MEDIVATION INC | 180,300 | 20,590,000 | 0.92% | ||
| 24 | ARIAD PHARMACEUTICALS INC | 2,231,717 | 18,456,000 | 0.82% | ||
| 25 | Heartware International, Inc. | 243,868 | 17,727,000 | 0.79% | ||
| 26 | ZELTIQ AESTHETICS INCORPORATED | 568,436 | 16,752,000 | 0.74% | ||
| 27 | RIGEL PHARMACEUTICAL INC | 5,176,319 | 16,616,000 | 0.74% | ||
| 28 | INTUITIVE SURGICAL INC | 32,350 | 15,674,000 | 0.70% | ||
| 29 | ALIMERA SCIENCES INC | 3,013,793 | 13,894,000 | 0.62% | ||
| 30 | EXACT SCIENCES CORP | 392,676 | 11,678,000 | 0.52% | ||
| 31 | Orexigen Therapeutics, Inc. | 1,931,324 | 9,560,000 | 0.43% | ||
| 32 | ACELRX PHARMACEUTICALS INC | 2,135,739 | 9,056,000 | 0.40% | ||
| 33 | IDERA PHARMACEUTICALS INC | 1,226,748 | 4,551,000 | 0.20% | ||
| 34 | XOMA CORP DEL | 799,000 | 3,100,000 | 0.14% | ||
| 35 | HISTOGENICS CORP | 454,545 | 2,936,000 | 0.13% | ||
| 36 | Sunesis Pharmaceuticals I | 906,263 | 2,728,000 | 0.12% | ||
| 37 | BIOSPECIFICS TECHNOLOGIES CORP COM | 50,436 | 2,602,000 | 0.12% | ||
| 38 | INTREXON CORP | 47,100 | 2,298,000 | 0.10% | ||
| 39 | ALIGN TECHNOLOGY INC | 27,757 | 1,741,000 | 0.08% | ||
| 40 | EPIZYME INC COM | 61,265 | 1,470,000 | 0.07% | ||
| 41 | ALCOBRA LTD | 156,588 | 1,024,000 | 0.05% | ||
| 42 | Dicerna Pharmaceuticals | 70,706 | 986,000 | 0.04% | ||
| 43 | CYTOKINETICS INC | 123,686 | 831,000 | 0.04% | ||
| 44 | MALLINCKRODT PUB LTD CO SHS | 3,588 | 422,000 | 0.02% | ||
| 45 | SOPHIRIS BIO INC | 191,600 | 150,000 | 0.01% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001306923-15-000019, filed 2015.08.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
