| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 3,641,425 | 26,036,000 | 23.94% | ||
| 2 | BAKER BROS. ADVISORS LP | 1,955,944 | 13,985,000 | 12.86% | ||
| 3 | Sarissa Capital Management LP | 1,132,367 | 8,096,000 | 7.45% | ||
| 4 | MILLENNIUM MANAGEMENT LLC | 770,676 | 5,510,000 | 5.07% | ||
| 5 | VANGUARD GROUP INC | 703,287 | 5,029,000 | 4.62% | ||
| 6 | BlackRock Institutional Trust Company, N.A. | 639,606 | 4,573,000 | 4.21% | ||
| 7 | GENERAL AMERICAN INVESTORS CO INC | 601,553 | 4,301,000 | 3.96% | ||
| 8 | BANK OF AMERICA CORP /DE/ | 522,274 | 3,734,000 | 3.43% | ||
| 9 | MORGAN STANLEY | 364,237 | 2,604,000 | 2.39% | ||
| 10 | DESTRIER CAPITAL MANAGEMENT LLC | 329,030 | 2,353,000 | 2.16% | ||
| 11 | Gruss Capital Management LP | 304,000 | 2,174,000 | 2.00% | ||
| 12 | NORTHERN TRUST CORP | 267,178 | 1,911,000 | 1.76% | ||
| 13 | HIGHLAND CAPITAL MANAGEMENT LP | 248,318 | 1,775,000 | 1.63% | ||
| 14 | CQS Cayman LP | 240,000 | 1,716,000 | 1.58% | ||
| 15 | RTW INVESTMENTS, LP | 229,364 | 1,640,000 | 1.51% | ||
| 16 | RENAISSANCE TECHNOLOGIES LLC | 202,143 | 1,445,000 | 1.33% | ||
| 17 | C WorldWide Group Holding A/S | 200,000 | 1,430,000 | 1.32% | ||
| 18 | ROYCE & ASSOCIATES LP | 191,000 | 1,366,000 | 1.26% | ||
| 19 | EDMOND DE ROTHSCHILD HOLDING S.A. | 182,500 | 1,305,000 | 1.20% | ||
| 20 | EDMOND DE ROTHSCHILD (SUISSE) S.A. | 182,500 | 1,305,000 | 1.20% | ||
| 21 | FULLER & THALER ASSET MANAGEMENT, INC. | 169,000 | 1,208,000 | 1.11% | ||
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 166,300 | 1,189,000 | 1.09% | Call | |
| 23 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 135,662 | 970,000 | 0.89% | ||
| 24 | DEUTSCHE BANK AG\ | 133,828 | 956,000 | 0.88% | ||
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 128,256 | 917,000 | 0.84% | ||
| 26 | GOLDMAN SACHS GROUP INC | 122,776 | 878,000 | 0.81% | ||
| 27 | D. E. Shaw & Co., Inc. | 122,723 | 877,000 | 0.81% | ||
| 28 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 118,000 | 844,000 | 0.78% | ||
| 29 | CREDIT SUISSE AG/ | 111,072 | 794,000 | 0.73% | ||
| 30 | GUGGENHEIM CAPITAL LLC | 105,453 | 755,000 | 0.69% | ||
| 31 | J. Goldman & Co LP | 101,881 | 728,000 | 0.67% | ||
| 32 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 89,400 | 639,000 | 0.59% | Put | |
| 33 | PDT Partners, LLC | 71,508 | 511,000 | 0.47% | ||
| 34 | BlackRock Fund Advisors | 61,829 | 442,000 | 0.41% | ||
| 35 | JANE STREET GROUP, LLC | 53,423 | 382,000 | 0.35% | ||
| 36 | TIAA CREF INVESTMENT MANAGEMENT LLC | 51,322 | 367,000 | 0.34% | ||
| 37 | Bank of New York Mellon Corp | 47,917 | 342,000 | 0.31% | ||
| 38 | AQR CAPITAL MANAGEMENT LLC | 47,097 | 337,000 | 0.31% | ||
| 39 | COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | 43,183 | 309,000 | 0.28% | ||
| 40 | Nine Chapters Capital Management LLC | 41,700 | 298,000 | 0.27% | ||
| 41 | SABBY MANAGEMENT, LLC | 41,643 | 298,000 | 0.27% | ||
| 42 | Paloma Partners Management Co | 37,400 | 267,000 | 0.25% | ||
| 43 | Parallax Volatility Advisers, L.P. | 35,000 | 250,000 | 0.23% | Put | |
| 44 | BARCLAYS PLC | 24,300 | 170,000 | 0.16% | Call | |
| 45 | LMR Partners LLP | 23,705 | 170,000 | 0.16% | ||
| 46 | STATE STREET CORP | 22,551 | 161,000 | 0.15% | ||
| 47 | Squarepoint Ops LLC | 18,800 | 134,000 | 0.12% | ||
| 48 | Alpine Global Management, LLC | 17,385 | 124,000 | 0.11% | ||
| 49 | BARCLAYS PLC | 17,479 | 122,000 | 0.11% | ||
| 50 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 16,188 | 116,000 | 0.11% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
