| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 3,031,056 | 30,220,000 | 17.22% | ||
| 2 | BAKER BROS. ADVISORS LP | 2,000,000 | 19,940,000 | 11.36% | ||
| 3 | Sarissa Capital Management LP | 1,132,367 | 11,290,000 | 6.43% | ||
| 4 | BlackRock Institutional Trust Company, N.A. | 849,971 | 8,474,000 | 4.83% | ||
| 5 | SENZAR ASSET MANAGEMENT, LLC | 764,406 | 7,621,000 | 4.34% | ||
| 6 | CQS Cayman LP | 700,000 | 6,979,000 | 3.98% | ||
| 7 | BlackRock Fund Advisors | 666,765 | 6,648,000 | 3.79% | ||
| 8 | VANGUARD GROUP INC | 650,225 | 6,483,000 | 3.69% | ||
| 9 | GENERAL AMERICAN INVESTORS CO INC | 508,375 | 5,068,000 | 2.89% | ||
| 10 | MILLENNIUM MANAGEMENT LLC | 383,604 | 3,825,000 | 2.18% | ||
| 11 | STATE STREET CORP | 359,459 | 3,588,000 | 2.04% | ||
| 12 | BANK OF AMERICA CORP /DE/ | 342,716 | 3,417,000 | 1.95% | ||
| 13 | DESTRIER CAPITAL MANAGEMENT LLC | 329,030 | 3,280,000 | 1.87% | ||
| 14 | FARALLON CAPITAL MANAGEMENT LLC | 300,000 | 2,991,000 | 1.70% | ||
| 15 | NORTHERN TRUST CORP | 293,991 | 2,931,000 | 1.67% | ||
| 16 | SABBY MANAGEMENT, LLC | 279,879 | 2,790,000 | 1.59% | ||
| 17 | Gruss Capital Management LP | 276,000 | 2,752,000 | 1.57% | ||
| 18 | ROYCE & ASSOCIATES LP | 251,000 | 2,502,000 | 1.43% | ||
| 19 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 236,300 | 2,356,000 | 1.34% | Call | |
| 20 | RTW INVESTMENTS, LP | 229,364 | 2,287,000 | 1.30% | ||
| 21 | J. Goldman & Co LP | 197,500 | 1,969,000 | 1.12% | Call | |
| 22 | MORGAN STANLEY | 188,340 | 1,878,000 | 1.07% | ||
| 23 | FULLER & THALER ASSET MANAGEMENT, INC. | 165,400 | 1,649,000 | 0.94% | ||
| 24 | GOLDMAN SACHS GROUP INC | 162,225 | 1,617,000 | 0.92% | ||
| 25 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 154,340 | 1,538,000 | 0.88% | ||
| 26 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 154,100 | 1,536,000 | 0.88% | Put | |
| 27 | Alden Global Capital Ltd | 154,000 | 1,535,000 | 0.87% | ||
| 28 | J. Goldman & Co LP | 142,500 | 1,421,000 | 0.81% | Put | |
| 29 | C WorldWide Group Holding A/S | 135,000 | 1,346,000 | 0.77% | ||
| 30 | Bank of New York Mellon Corp | 133,578 | 1,332,000 | 0.76% | ||
| 31 | GEODE CAPITAL MANAGEMENT, LLC | 127,269 | 1,268,000 | 0.72% | ||
| 32 | TIAA CREF INVESTMENT MANAGEMENT LLC | 126,811 | 1,264,000 | 0.72% | ||
| 33 | J. Goldman & Co LP | 126,000 | 1,256,000 | 0.72% | ||
| 34 | BARCLAYS PLC | 128,685 | 1,158,000 | 0.66% | ||
| 35 | GOLDMAN SACHS GROUP INC | 112,800 | 1,125,000 | 0.64% | Call | |
| 36 | BARCLAYS PLC | 122,900 | 1,106,000 | 0.63% | Call | |
| 37 | Spot Trading L.L.C | 103,020 | 1,027,000 | 0.59% | ||
| 38 | SPHERA FUNDS MANAGEMENT LTD. | 100,000 | 997,000 | 0.57% | ||
| 39 | HIGHLAND CAPITAL MANAGEMENT LP | 93,941 | 937,000 | 0.53% | ||
| 40 | GUGGENHEIM CAPITAL LLC | 80,353 | 802,000 | 0.46% | ||
| 41 | Spot Trading L.L.C | 80,100 | 799,000 | 0.46% | Put | |
| 42 | PDT Partners, LLC | 71,705 | 715,000 | 0.41% | ||
| 43 | BlackRock Investment Management, LLC | 70,146 | 699,000 | 0.40% | ||
| 44 | GOLDMAN SACHS GROUP INC | 70,000 | 698,000 | 0.40% | Put | |
| 45 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 62,596 | 624,000 | 0.36% | ||
| 46 | BANK OF MONTREAL /CAN/ | 57,200 | 570,000 | 0.32% | Call | |
| 47 | CREDIT SUISSE AG/ | 52,582 | 525,000 | 0.30% | ||
| 48 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 52,133 | 520,000 | 0.30% | ||
| 49 | INTEGRAL DERIVATIVES, LLC | 46,800 | 467,000 | 0.27% | Put | |
| 50 | BARCLAYS PLC | 51,100 | 460,000 | 0.26% | Put |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
