| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | VIVO CAPITAL, LLC | 12,814,286 | 4,793,000 | 46.91% | ||
| 2 | FRANKLIN RESOURCES INC | 9,499,615 | 3,553,000 | 34.78% | ||
| 3 | EcoR1 Capital, LLC | 1,342,000 | 502,000 | 4.91% | ||
| 4 | RTW INVESTMENTS, LP | 1,273,128 | 476,000 | 4.66% | ||
| 5 | Sio Capital Management, LLC | 1,143,400 | 428,000 | 4.19% | ||
| 6 | SABBY MANAGEMENT, LLC | 708,046 | 265,000 | 2.59% | ||
| 7 | VANGUARD GROUP INC | 264,885 | 100,000 | 0.98% | ||
| 8 | PANAGORA ASSET MANAGEMENT INC | 80,735 | 30,000 | 0.29% | ||
| 9 | DAFNA Capital Management LLC | 77,031 | 29,000 | 0.28% | ||
| 10 | LPL Financial LLC | 40,000 | 15,000 | 0.15% | ||
| 11 | FIRST WILSHIRE SECURITIES MANAGEMENT INC | 28,027 | 10,000 | 0.10% | ||
| 12 | TWO SIGMA SECURITIES, LLC | 10,447 | 4,000 | 0.04% | ||
| 13 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 11,000 | 4,000 | 0.04% | ||
| 14 | Virtu KCG Holdings LLC | 11,460 | 4,000 | 0.04% | ||
| 15 | UBS Group AG | 7,147 | 3,000 | 0.03% | ||
| 16 | BlackRock Fund Advisors | 2,643 | 1,000 | 0.01% | ||
| 17 | MINICHMACGREGOR WEALTH MANAGEMENT, LLC | 650 | 0 | 0.00% | ||
| 18 | WELLS FARGO & COMPANY/MN | 75 | 0 | 0.00% | ||
| 19 | BANK OF AMERICA CORP /DE/ | 1 | 0 | 0.00% | ||
| 20 | MORGAN STANLEY | 100 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
