| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Devon Park Associates, LLC | 3,243,709 | 24,003,000 | 16.95% | ||
| 2 | RHO CAPITAL PARTNERS INC | 2,627,790 | 19,446,000 | 13.74% | ||
| 3 | JENNISON ASSOCIATES LLC | 1,949,941 | 14,430,000 | 10.19% | ||
| 4 | FRANKLIN RESOURCES INC | 1,525,800 | 11,291,000 | 7.98% | ||
| 5 | ORBIMED ADVISORS LLC | 1,391,000 | 10,293,000 | 7.27% | ||
| 6 | Point72 Asset Management, L.P. | 1,003,402 | 7,425,000 | 5.24% | ||
| 7 | BLACKROCK ADVISORS LLC | 750,584 | 5,554,000 | 3.92% | ||
| 8 | SENZAR ASSET MANAGEMENT, LLC | 747,900 | 5,534,460 | 3.91% | ||
| 9 | PRICE T ROWE ASSOCIATES INC /MD/ | 728,933 | 5,394,000 | 3.81% | ||
| 10 | EverPoint Asset Management, LLC | 702,927 | 5,202,000 | 3.67% | ||
| 11 | VANGUARD GROUP INC | 527,516 | 3,903,000 | 2.76% | ||
| 12 | Tekla Capital Management LLC | 487,392 | 3,607,000 | 2.55% | ||
| 13 | BlackRock Fund Advisors | 359,612 | 2,661,000 | 1.88% | ||
| 14 | BlackRock Group LTD | 344,607 | 2,550,000 | 1.80% | ||
| 15 | GW&K Investment Management, LLC | 320,759 | 2,374,000 | 1.68% | ||
| 16 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 275,000 | 2,035,000 | 1.44% | ||
| 17 | BlackRock Institutional Trust Company, N.A. | 261,632 | 1,936,000 | 1.37% | ||
| 18 | SPHERA FUNDS MANAGEMENT LTD. | 250,000 | 1,850,000 | 1.31% | ||
| 19 | COLUMBUS CIRCLE INVESTORS | 183,271 | 1,356,000 | 0.96% | ||
| 20 | FT OPTIONS LLC | 169,551 | 1,255,000 | 0.89% | ||
| 21 | SABBY MANAGEMENT, LLC | 116,454 | 862,000 | 0.61% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 82,072 | 607,000 | 0.43% | ||
| 23 | BlackRock Finance, Inc. | 80,811 | 598,000 | 0.42% | ||
| 24 | MORGAN STANLEY | 79,653 | 590,000 | 0.42% | ||
| 25 | PUTNAM INVESTMENTS LLC | 79,225 | 586,000 | 0.41% | ||
| 26 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 77,232 | 572,000 | 0.40% | ||
| 27 | PURA VIDA INVESTMENTS, LLC | 75,000 | 555,000 | 0.39% | ||
| 28 | GRATICULE ASIA MACRO ADVISORS LLC | 66,517 | 492,000 | 0.35% | ||
| 29 | CREDIT SUISSE AG/ | 50,502 | 374,000 | 0.26% | ||
| 30 | GOLDMAN SACHS GROUP INC | 46,397 | 343,000 | 0.24% | ||
| 31 | JPMORGAN CHASE & CO | 43,947 | 325,000 | 0.23% | ||
| 32 | BlackRock Investment Management, LLC | 41,652 | 308,000 | 0.22% | ||
| 33 | UBS Group AG | 38,623 | 286,000 | 0.20% | ||
| 34 | TWO SIGMA ADVISERS, LP | 38,300 | 283,000 | 0.20% | ||
| 35 | MILLENNIUM MANAGEMENT LLC | 36,892 | 273,000 | 0.19% | ||
| 36 | Bank of New York Mellon Corp | 32,969 | 244,000 | 0.17% | ||
| 37 | D. E. Shaw & Co., Inc. | 32,845 | 243,000 | 0.17% | ||
| 38 | TD ASSET MANAGEMENT INC | 32,200 | 238,000 | 0.17% | ||
| 39 | ALPS ADVISORS INC | 29,701 | 220,000 | 0.16% | ||
| 40 | DEUTSCHE BANK AG\ | 29,433 | 217,000 | 0.15% | ||
| 41 | Segantii Capital Management Ltd | 24,800 | 182,000 | 0.13% | ||
| 42 | Janney Montgomery Scott LLC | 23,665 | 175,000 | 0.12% | ||
| 43 | NORTHERN TRUST CORP | 19,959 | 148,000 | 0.10% | ||
| 44 | ProShare Advisors LLC | 19,405 | 144,000 | 0.10% | ||
| 45 | NOMURA HOLDINGS INC | 18,042 | 133,000 | 0.09% | ||
| 46 | A.R.T. Advisors, LLC | 14,001 | 103,000 | 0.07% | ||
| 47 | SG Americas Securities, LLC | 11,620 | 86,000 | 0.06% | ||
| 48 | DekaBank Deutsche Girozentrale | 11,500 | 85,000 | 0.06% | ||
| 49 | BANK OF MONTREAL /CAN/ | 9,000 | 67,000 | 0.05% | ||
| 50 | WELLS FARGO & COMPANY/MN | 8,572 | 63,000 | 0.04% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
