| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Devon Park Associates, LLC | 3,243,709 | 36,751,000 | 16.88% | ||
| 2 | RHO CAPITAL PARTNERS INC | 2,627,790 | 29,773,000 | 13.67% | ||
| 3 | JENNISON ASSOCIATES LLC | 1,919,852 | 21,752,000 | 9.99% | ||
| 4 | RS INVESTMENT MANAGEMENT CO LLC | 1,585,006 | 17,958,000 | 8.25% | ||
| 5 | FRANKLIN RESOURCES INC | 1,525,800 | 17,287,000 | 7.94% | ||
| 6 | Point72 Asset Management, L.P. | 1,148,100 | 13,008,000 | 5.97% | ||
| 7 | PRICE T ROWE ASSOCIATES INC /MD/ | 735,063 | 8,328,000 | 3.82% | ||
| 8 | EverPoint Asset Management, LLC | 692,180 | 7,842,000 | 3.60% | ||
| 9 | BLACKROCK ADVISORS LLC | 664,484 | 7,529,000 | 3.46% | ||
| 10 | VANGUARD GROUP INC | 464,735 | 5,266,000 | 2.42% | ||
| 11 | ORBIMED ADVISORS LLC | 425,000 | 4,815,000 | 2.21% | ||
| 12 | Tekla Capital Management LLC | 425,000 | 4,815,000 | 2.21% | ||
| 13 | SPHERA FUNDS MANAGEMENT LTD. | 360,000 | 4,079,000 | 1.87% | ||
| 14 | BlackRock Group LTD | 344,607 | 3,904,000 | 1.79% | ||
| 15 | Private Capital Advisors, Inc. | 341,000 | 3,864,000 | 1.77% | ||
| 16 | BlackRock Fund Advisors | 326,618 | 3,701,000 | 1.70% | ||
| 17 | SENZAR ASSET MANAGEMENT, LLC | 309,600 | 3,507,768 | 1.61% | ||
| 18 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 275,000 | 3,116,000 | 1.43% | ||
| 19 | BlackRock Institutional Trust Company, N.A. | 261,632 | 2,964,000 | 1.36% | ||
| 20 | GW&K Investment Management, LLC | 168,405 | 1,908,000 | 0.88% | ||
| 21 | GRATICULE ASIA MACRO ADVISORS LLC | 148,000 | 1,676,000 | 0.77% | ||
| 22 | Informed Momentum Co LLC | 128,911 | 1,461,000 | 0.67% | ||
| 23 | COLUMBUS CIRCLE INVESTORS | 120,867 | 1,369,000 | 0.63% | ||
| 24 | SABBY MANAGEMENT, LLC | 87,652 | 993,000 | 0.46% | ||
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 82,126 | 930,000 | 0.43% | ||
| 26 | BlackRock Finance, Inc. | 80,811 | 916,000 | 0.42% | ||
| 27 | PUTNAM INVESTMENTS LLC | 78,953 | 895,000 | 0.41% | ||
| 28 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 69,117 | 783,000 | 0.36% | ||
| 29 | TWO SIGMA ADVISERS, LP | 63,400 | 718,000 | 0.33% | ||
| 30 | NEXTHERA CAPITAL LP | 42,000 | 476,000 | 0.22% | ||
| 31 | ACADIAN ASSET MANAGEMENT LLC | 40,827 | 462,000 | 0.21% | ||
| 32 | BlackRock Investment Management, LLC | 36,052 | 408,000 | 0.19% | ||
| 33 | ALPS ADVISORS INC | 34,791 | 394,000 | 0.18% | ||
| 34 | TD ASSET MANAGEMENT INC | 33,200 | 376,000 | 0.17% | ||
| 35 | Janney Montgomery Scott LLC | 31,015 | 351,000 | 0.16% | ||
| 36 | FEDERATED HERMES, INC. | 30,000 | 340,000 | 0.16% | ||
| 37 | DEUTSCHE BANK AG\ | 29,585 | 334,000 | 0.15% | ||
| 38 | PURA VIDA INVESTMENTS, LLC | 26,800 | 304,000 | 0.14% | ||
| 39 | FT OPTIONS LLC | 26,421 | 299,000 | 0.14% | ||
| 40 | ProShare Advisors LLC | 21,237 | 241,000 | 0.11% | ||
| 41 | NORTHERN TRUST CORP | 18,513 | 210,000 | 0.10% | ||
| 42 | Bank of New York Mellon Corp | 17,950 | 203,000 | 0.09% | ||
| 43 | MILLENNIUM MANAGEMENT LLC | 17,412 | 197,000 | 0.09% | ||
| 44 | CREDIT SUISSE AG/ | 16,741 | 189,000 | 0.09% | ||
| 45 | MORGAN STANLEY | 14,898 | 169,000 | 0.08% | ||
| 46 | D. E. Shaw & Co., Inc. | 14,645 | 166,000 | 0.08% | ||
| 47 | Meditor Group Ltd | 12,594 | 142,000 | 0.07% | ||
| 48 | OXFORD ASSET MANAGEMENT LLP | 10,075 | 115,000 | 0.05% | ||
| 49 | PANAGORA ASSET MANAGEMENT INC | 9,378 | 106,000 | 0.05% | ||
| 50 | BANK OF MONTREAL /CAN/ | 9,000 | 102,000 | 0.05% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
