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SYNERGY PHARMACEUTICALS DEL COM NEW
SYNERGY PHARMACEUTICALS DEL COM NEW. Institutional holdings reported to the SEC.

Institutional Holders (2014Q1)
Portfolio Summary: 86 Institutional holders with a total value of $144,453,033.
#
Manager Name
Shares
Value ($)
%
Options
Notes
1 VANGUARD GROUP INC 4,518,972 23,996,000 16.61%
2 STATE STREET CORP 3,387,686 17,991,000 12.45%
3 BlackRock Fund Advisors 3,368,927 17,889,000 12.38%
4 FMR LLC 2,653,656 14,091,000 9.75%
5 BAKER BROS. ADVISORS LP 1,758,271 9,336,000 6.46%
6 BlackRock Institutional Trust Company, N.A. 1,028,245 5,460,000 3.78%
7 NORTHERN TRUST CORP 1,023,922 5,437,000 3.76%
8 WALL STREET ASSOCIATES 950,000 5,044,000 3.49%
9 MORGAN STANLEY 830,800 4,412,000 3.05%
10 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 619,800 3,291,000 2.28%
11 Cambridge Investment Research Advisors, Inc. 441,290 2,343,000 1.62%
12 GEODE CAPITAL MANAGEMENT, LLC 441,016 2,341,000 1.62%
13 OXFORD ASSET MANAGEMENT LLP 414,311 2,200,000 1.52%
14 Bank of New York Mellon Corp 385,616 2,048,000 1.42%
15 HighTower Advisors, LLC 354,026 1,880,000 1.30%
16 TIAA CREF INVESTMENT MANAGEMENT LLC 312,595 1,660,000 1.15%
17 SUSQUEHANNA INTERNATIONAL GROUP, LLP 273,500 1,452,000 1.01% Call
18 THOMPSON SIEGEL & WALMSLEY LLC 257,734 1,369,000 0.95%
19 Belmont Global Advisors, Inc. 250,000 1,327,000 0.92%
20 BlackRock Investment Management, LLC 224,131 1,190,000 0.82%
21 SUSQUEHANNA INTERNATIONAL GROUP, LLP 222,579 1,182,000 0.82%
22 RENAISSANCE TECHNOLOGIES LLC 197,390 1,048,000 0.73%
23 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 191,485 1,017,000 0.70%
24 Trellus Management Company, LLC 155,800 827,000 0.57%
25 ProShare Advisors LLC 150,610 800,000 0.55%
26 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 145,878 775,000 0.54%
27 SABBY MANAGEMENT, LLC 377,908 718,000 0.50%
28 UBS AG 134,850 716,000 0.50%
29 CREDIT SUISSE AG/ 130,193 691,000 0.48%
30 SUSQUEHANNA INTERNATIONAL GROUP, LLP 121,900 647,000 0.45% Put
31 TEACHERS ADVISORS, LLC 119,658 635,000 0.44%
32 ALLIANCEBERNSTEIN L.P. 118,000 627,000 0.43%
33 BAILARD, INC. 115,500 613,000 0.42%
34 DEUTSCHE BANK AG\ 113,019 599,000 0.41%
35 Alpine Global Management, LLC 100,000 531,000 0.37%
36 STONERIDGE INVESTMENT PARTNERS LLC 98,958 525,000 0.36%
37 MILLENNIUM MANAGEMENT LLC 84,005 446,000 0.31%
38 Swiss National Bank 79,700 423,000 0.29%
39 Absolute Return Capital, LLC 77,675 412,000 0.29%
40 RHUMBLINE ADVISERS 67,559 359,000 0.25%
41 METROPOLITAN LIFE INSURANCE CO/NY 67,438 358,000 0.25%
42 GOLDMAN SACHS GROUP INC 64,035 340,000 0.24%
43 MANUFACTURERS LIFE INSURANCE COMPANY, THE 62,338 331,000 0.23%
44 VOYA INVESTMENT MANAGEMENT LLC 61,742 328,000 0.23%
45 Nationwide Fund Advisors 61,845 328,000 0.23%
46 AMERICAN INTERNATIONAL GROUP, INC. 58,658 311,474 0.22%
47 DekaBank Deutsche Girozentrale 55,000 292,000 0.20%
48 WELLS FARGO & COMPANY/MN 53,978 287,000 0.20%
49 BANK OF AMERICA CORP /DE/ 52,500 279,000 0.19%
50 JPMORGAN CHASE & CO 48,026 255,000 0.18%
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From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.