| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FLAGSHIP VENTURES FUND IV GENERAL PARTNER LLC | 14,083,579 | 494,193,000 | 47.81% | ||
| 2 | FMR LLC | 5,858,365 | 205,570,000 | 19.89% | ||
| 3 | PRICE T ROWE ASSOCIATES INC /MD/ | 961,650 | 33,744,000 | 3.26% | ||
| 4 | FEDERATED HERMES, INC. | 694,980 | 24,387,000 | 2.36% | ||
| 5 | BlackRock Fund Advisors | 662,077 | 23,232,000 | 2.25% | ||
| 6 | Flagship Ventures 2007 General Partner LLC | 599,297 | 21,029,000 | 2.03% | ||
| 7 | WADDELL & REED FINANCIAL INC | 585,567 | 20,548,000 | 1.99% | ||
| 8 | VANGUARD GROUP INC | 544,752 | 19,115,000 | 1.85% | ||
| 9 | TimesSquare Capital Management, LLC | 500,000 | 17,545,000 | 1.70% | ||
| 10 | JENNISON ASSOCIATES LLC | 398,959 | 13,999,000 | 1.35% | ||
| 11 | BRIDGER MANAGEMENT, LLC | 381,300 | 13,380,000 | 1.29% | ||
| 12 | ALLIANCEBERNSTEIN L.P. | 378,136 | 13,269,000 | 1.28% | ||
| 13 | Capital World Investors | 352,500 | 12,369,000 | 1.20% | ||
| 14 | BLACKROCK ADVISORS LLC | 340,871 | 11,962,000 | 1.16% | ||
| 15 | Cormorant Asset Management, LP | 250,000 | 8,773,000 | 0.85% | ||
| 16 | Rock Springs Capital Management LP | 245,400 | 8,611,000 | 0.83% | ||
| 17 | JPMORGAN CHASE & CO | 202,947 | 7,122,000 | 0.69% | ||
| 18 | BlackRock Group LTD | 196,300 | 6,888,000 | 0.67% | ||
| 19 | BlackRock Institutional Trust Company, N.A. | 192,006 | 6,737,000 | 0.65% | ||
| 20 | EVENTIDE ASSET MANAGEMENT, LLC | 178,200 | 6,253,000 | 0.60% | ||
| 21 | MILLENNIUM MANAGEMENT LLC | 175,503 | 6,158,000 | 0.60% | ||
| 22 | Artal Group S.A. | 175,000 | 6,141,000 | 0.59% | ||
| 23 | ORBIMED ADVISORS LLC | 166,645 | 5,848,000 | 0.57% | ||
| 24 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 136,750 | 4,799,000 | 0.46% | ||
| 25 | BAKER BROS. ADVISORS LP | 125,000 | 4,386,000 | 0.42% | ||
| 26 | STATE STREET CORP | 116,203 | 4,078,000 | 0.39% | ||
| 27 | NORTHERN TRUST CORP | 90,493 | 3,175,000 | 0.31% | ||
| 28 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 87,021 | 3,054,000 | 0.30% | ||
| 29 | LORD, ABBETT & CO. LLC | 82,873 | 2,908,000 | 0.28% | ||
| 30 | GEODE CAPITAL MANAGEMENT, LLC | 75,109 | 2,635,000 | 0.25% | ||
| 31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 70,400 | 2,470,000 | 0.24% | Call | |
| 32 | BlackRock Investment Management, LLC | 49,398 | 1,733,000 | 0.17% | ||
| 33 | BlackRock Finance, Inc. | 47,800 | 1,677,000 | 0.16% | ||
| 34 | Bank of New York Mellon Corp | 35,110 | 1,232,000 | 0.12% | ||
| 35 | GOLDMAN SACHS GROUP INC | 35,000 | 1,228,000 | 0.12% | Call | |
| 36 | GOLDMAN SACHS GROUP INC | 35,000 | 1,228,000 | 0.12% | Put | |
| 37 | MORGAN STANLEY | 33,758 | 1,185,000 | 0.11% | ||
| 38 | Opus Point Partners Management, LLC | 33,000 | 1,158,000 | 0.11% | ||
| 39 | ProShare Advisors LLC | 32,660 | 1,146,000 | 0.11% | ||
| 40 | TIAA CREF INVESTMENT MANAGEMENT LLC | 25,459 | 893,000 | 0.09% | ||
| 41 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 24,400 | 856,000 | 0.08% | Put | |
| 42 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 23,033 | 809,000 | 0.08% | ||
| 43 | GOLDMAN SACHS GROUP INC | 21,129 | 741,000 | 0.07% | ||
| 44 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 15,919 | 559,000 | 0.05% | ||
| 45 | TD ASSET MANAGEMENT INC | 14,900 | 523,000 | 0.05% | ||
| 46 | KENNEDY CAPITAL MANAGEMENT LLC | 14,436 | 507,000 | 0.05% | ||
| 47 | TEACHERS ADVISORS, LLC | 12,747 | 447,000 | 0.04% | ||
| 48 | SABBY MANAGEMENT, LLC | 10,495 | 368,000 | 0.04% | ||
| 49 | Swiss National Bank | 10,200 | 358,000 | 0.03% | ||
| 50 | CREDIT SUISSE AG/ | 8,639 | 303,000 | 0.03% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
