| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FLAGSHIP VENTURES FUND IV GENERAL PARTNER LLC | 12,682,876 | 368,438,000 | 39.99% | ||
| 2 | FMR LLC | 5,927,976 | 172,207,000 | 18.69% | ||
| 3 | FEDERATED HERMES, INC. | 1,990,934 | 57,837,000 | 6.28% | ||
| 4 | VANGUARD GROUP INC | 1,176,924 | 34,191,000 | 3.71% | ||
| 5 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,147,577 | 33,337,000 | 3.62% | ||
| 6 | BlackRock Fund Advisors | 927,471 | 26,943,000 | 2.92% | ||
| 7 | WADDELL & REED FINANCIAL INC | 734,715 | 21,344,000 | 2.32% | ||
| 8 | JENNISON ASSOCIATES LLC | 670,639 | 19,482,000 | 2.11% | ||
| 9 | BRIDGER MANAGEMENT, LLC | 624,199 | 18,133,000 | 1.97% | ||
| 10 | TimesSquare Capital Management, LLC | 491,085 | 14,266,000 | 1.55% | ||
| 11 | ALLIANCEBERNSTEIN L.P. | 416,740 | 12,106,000 | 1.31% | ||
| 12 | COLUMBUS CIRCLE INVESTORS | 367,502 | 10,676,000 | 1.16% | ||
| 13 | Capital World Investors | 352,500 | 10,240,000 | 1.11% | ||
| 14 | Artal Group S.A. | 310,000 | 9,006,000 | 0.98% | ||
| 15 | BlackRock Institutional Trust Company, N.A. | 278,898 | 8,102,000 | 0.88% | ||
| 16 | Rock Springs Capital Management LP | 262,000 | 7,611,000 | 0.83% | ||
| 17 | STATE STREET CORP | 255,095 | 7,408,000 | 0.80% | ||
| 18 | Cormorant Asset Management, LP | 253,064 | 7,352,000 | 0.80% | ||
| 19 | JPMORGAN CHASE & CO | 212,617 | 6,176,000 | 0.67% | ||
| 20 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 189,667 | 5,510,000 | 0.60% | ||
| 21 | NORTHERN TRUST CORP | 179,822 | 5,224,000 | 0.57% | ||
| 22 | EVENTIDE ASSET MANAGEMENT, LLC | 178,200 | 5,177,000 | 0.56% | ||
| 23 | CQS Cayman LP | 162,000 | 4,706,000 | 0.51% | ||
| 24 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 144,323 | 4,193,000 | 0.46% | ||
| 25 | Portolan Capital Management, LLC | 133,883 | 3,889,000 | 0.42% | ||
| 26 | BAKER BROS. ADVISORS LP | 125,000 | 3,631,000 | 0.39% | ||
| 27 | GREAT POINT PARTNERS LLC | 120,000 | 3,486,000 | 0.38% | Put | |
| 28 | AMERICAN CENTURY COMPANIES INC | 108,878 | 3,163,000 | 0.34% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 89,929 | 2,612,000 | 0.28% | ||
| 30 | ORBIMED ADVISORS LLC | 86,000 | 2,498,000 | 0.27% | ||
| 31 | BlackRock Investment Management, LLC | 68,652 | 1,994,000 | 0.22% | ||
| 32 | BLACKROCK ADVISORS LLC | 58,672 | 1,704,000 | 0.18% | ||
| 33 | Opaleye Management Inc. | 57,500 | 1,670,000 | 0.18% | ||
| 34 | Bank of New York Mellon Corp | 57,270 | 1,664,000 | 0.18% | ||
| 35 | ALPS ADVISORS INC | 55,517 | 1,613,000 | 0.18% | ||
| 36 | TIAA CREF INVESTMENT MANAGEMENT LLC | 53,093 | 1,542,000 | 0.17% | ||
| 37 | Iguana Healthcare Management, LLC | 50,000 | 1,453,000 | 0.16% | ||
| 38 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 39,470 | 1,147,000 | 0.12% | ||
| 39 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 37,600 | 1,092,000 | 0.12% | Call | |
| 40 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 37,380 | 1,086,000 | 0.12% | ||
| 41 | MORGAN STANLEY | 35,215 | 1,023,000 | 0.11% | ||
| 42 | OXFORD ASSET MANAGEMENT LLP | 34,988 | 1,016,000 | 0.11% | ||
| 43 | TD ASSET MANAGEMENT INC | 31,882 | 926,000 | 0.10% | ||
| 44 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 31,700 | 921,000 | 0.10% | Put | |
| 45 | ProShare Advisors LLC | 31,599 | 918,000 | 0.10% | ||
| 46 | TEACHERS ADVISORS, LLC | 28,639 | 832,000 | 0.09% | ||
| 47 | HAMILTON LANE ADVISORS LLC | 24,883 | 757,000 | 0.08% | ||
| 48 | Swiss National Bank | 23,700 | 688,000 | 0.07% | ||
| 49 | WELLINGTON MANAGEMENT GROUP LLP | 22,500 | 654,000 | 0.07% | ||
| 50 | DekaBank Deutsche Girozentrale | 20,300 | 606,000 | 0.07% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
