| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 7,259,620 | 19,964,000 | 42.85% | ||
| 2 | Tekla Capital Management LLC | 3,848,191 | 10,583,000 | 22.72% | ||
| 3 | Lombard Odier Asset Management (USA) Corp | 2,590,909 | 7,125,000 | 15.29% | ||
| 4 | SPHERA FUNDS MANAGEMENT LTD. | 1,200,000 | 3,300,000 | 7.08% | ||
| 5 | EMERALD MUTUAL FUND ADVISERS TRUST | 905,628 | 2,490,000 | 5.34% | ||
| 6 | Green Owl Capital Management, LLC | 450,000 | 1,238,000 | 2.66% | ||
| 7 | Pine River Capital Management L.P. | 350,000 | 963,000 | 2.07% | ||
| 8 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 129,390 | 356,000 | 0.76% | ||
| 9 | DAFNA Capital Management LLC | 125,000 | 344,000 | 0.74% | ||
| 10 | EMERALD ADVISERS, LLC | 52,263 | 144,000 | 0.31% | ||
| 11 | THOMPSON DAVIS & CO., INC. | 22,500 | 62,000 | 0.13% | ||
| 12 | UBS Group AG | 6,080 | 17,000 | 0.04% | ||
| 13 | Tower Research Capital LLC (TRC) | 500 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
