| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Capital Research Global Investors | 19,257,744 | 1,871,082,000 | 13.58% | ||
| 2 | FMR LLC | 13,431,589 | 1,214,216,000 | 8.82% | ||
| 3 | SANDS CAPITAL MANAGEMENT, LLC | 12,183,113 | 1,101,353,000 | 8.00% | ||
| 4 | VANGUARD GROUP INC | 8,848,001 | 799,859,000 | 5.81% | ||
| 5 | PRIMECAP MANAGEMENT CO/CA/ | 8,016,518 | 724,693,000 | 5.26% | ||
| 6 | JENNISON ASSOCIATES LLC | 5,660,987 | 511,753,000 | 3.72% | ||
| 7 | BAKER BROS. ADVISORS LP | 3,713,950 | 335,741,000 | 2.44% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 3,525,165 | 318,675,000 | 2.31% | ||
| 9 | BlackRock Fund Advisors | 2,951,920 | 266,854,000 | 1.94% | ||
| 10 | BLAIR WILLIAM & CO/IL | 2,702,589 | 244,314,000 | 1.77% | ||
| 11 | STATE STREET CORP | 2,655,618 | 240,057,000 | 1.74% | ||
| 12 | TCW GROUP INC | 2,458,378 | 222,238,000 | 1.61% | ||
| 13 | Blue Ridge Capital, L.L.C. | 2,230,000 | 201,592,000 | 1.46% | ||
| 14 | Temasek Holdings (Private) Ltd | 2,132,778 | 192,803,000 | 1.40% | ||
| 15 | TIAA CREF INVESTMENT MANAGEMENT LLC | 2,101,449 | 189,971,000 | 1.38% | ||
| 16 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,938,782 | 175,266,000 | 1.27% | ||
| 17 | WELLS FARGO & COMPANY/MN | 1,912,243 | 172,867,000 | 1.26% | ||
| 18 | OppenheimerFunds, Inc. | 1,767,408 | 159,774,000 | 1.16% | ||
| 19 | FRANKLIN RESOURCES INC | 1,583,765 | 143,172,000 | 1.04% | ||
| 20 | Amici Capital, LLC | 1,522,087 | 137,597,000 | 1.00% | ||
| 21 | WADDELL & REED FINANCIAL INC | 1,519,938 | 137,402,000 | 1.00% | ||
| 22 | CITADEL ADVISORS LLC | 1,458,203 | 131,822,000 | 0.96% | ||
| 23 | VICTORY CAPITAL MANAGEMENT INC | 1,437,302 | 129,932,000 | 0.94% | ||
| 24 | Palo Alto Investors LP | 1,302,197 | 117,719,000 | 0.85% | ||
| 25 | NORTHERN TRUST CORP | 1,299,541 | 117,478,000 | 0.85% | ||
| 26 | SECTORAL ASSET MANAGEMENT INC | 1,253,243 | 113,293,000 | 0.82% | ||
| 27 | BlackRock Group LTD | 1,222,150 | 110,483,000 | 0.80% | ||
| 28 | FIRST TRUST ADVISORS LP | 1,176,560 | 106,361,000 | 0.77% | ||
| 29 | DEUTSCHE BANK AG\ | 1,152,209 | 104,156,000 | 0.76% | ||
| 30 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,145,474 | 103,551,000 | 0.75% | ||
| 31 | GILDER GAGNON HOWE & CO LLC | 1,063,262 | 96,119,000 | 0.70% | ||
| 32 | BLACKROCK ADVISORS LLC | 1,055,719 | 95,437,000 | 0.69% | ||
| 33 | NORGES BANK | 1,044,603 | 94,432,000 | 0.69% | ||
| 34 | Visium Asset Management, LP | 988,391 | 89,352,000 | 0.65% | ||
| 35 | MILLENNIUM MANAGEMENT LLC | 916,432 | 82,845,000 | 0.60% | ||
| 36 | Invesco Ltd. | 888,237 | 80,297,000 | 0.58% | ||
| 37 | GEODE CAPITAL MANAGEMENT, LLC | 781,154 | 70,578,000 | 0.51% | ||
| 38 | USS Investment Management Ltd | 739,334 | 66,836,000 | 0.49% | ||
| 39 | AMERIPRISE FINANCIAL INC | 728,279 | 65,835,000 | 0.48% | ||
| 40 | ALKEON CAPITAL MANAGEMENT LLC | 726,175 | 65,646,000 | 0.48% | ||
| 41 | FIL Ltd | 715,590 | 64,690,000 | 0.47% | ||
| 42 | ALTRINSIC GLOBAL ADVISORS LLC | 713,218 | 64,475,000 | 0.47% | ||
| 43 | Clearbridge Investments, LLC | 699,390 | 63,225,000 | 0.46% | ||
| 44 | Bank of New York Mellon Corp | 601,053 | 54,336,000 | 0.39% | ||
| 45 | CREDIT SUISSE AG/ | 584,942 | 52,880,000 | 0.38% | ||
| 46 | Legal & General Group Plc | 572,095 | 51,717,000 | 0.38% | ||
| 47 | Tekla Capital Management LLC | 570,027 | 51,530,000 | 0.37% | ||
| 48 | BANK OF AMERICA CORP /DE/ | 554,242 | 50,103,000 | 0.36% | ||
| 49 | JPMORGAN CHASE & CO | 554,199 | 50,099,000 | 0.36% | ||
| 50 | FRONTIER CAPITAL MANAGEMENT CO LLC | 539,209 | 48,744,000 | 0.35% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
