| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Capital Research Global Investors | 15,853,295 | 1,307,580,000 | 9.62% | ||
| 2 | FMR LLC | 13,459,463 | 1,110,136,000 | 8.17% | ||
| 3 | SANDS CAPITAL MANAGEMENT, LLC | 11,561,504 | 953,593,000 | 7.02% | ||
| 4 | VANGUARD GROUP INC | 11,102,321 | 915,720,000 | 6.74% | ||
| 5 | JENNISON ASSOCIATES LLC | 8,749,891 | 721,691,000 | 5.31% | ||
| 6 | PRIMECAP MANAGEMENT CO/CA/ | 7,350,369 | 606,258,000 | 4.46% | ||
| 7 | PRICE T ROWE ASSOCIATES INC /MD/ | 6,218,760 | 512,923,000 | 3.78% | ||
| 8 | BAKER BROS. ADVISORS LP | 4,806,483 | 396,439,000 | 2.92% | ||
| 9 | JPMORGAN CHASE & CO | 4,486,438 | 370,041,000 | 2.72% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 3,809,516 | 314,209,000 | 2.31% | ||
| 11 | BlackRock Fund Advisors | 3,683,333 | 303,801,000 | 2.24% | ||
| 12 | Temasek Holdings (Private) Ltd | 3,472,712 | 286,429,000 | 2.11% | ||
| 13 | STATE STREET CORP | 3,286,743 | 271,074,000 | 2.00% | ||
| 14 | WELLS FARGO & COMPANY/MN | 2,656,812 | 219,134,000 | 1.61% | ||
| 15 | Invesco Ltd. | 2,464,645 | 203,285,000 | 1.50% | ||
| 16 | CITADEL ADVISORS LLC | 2,194,875 | 181,033,000 | 1.33% | ||
| 17 | OppenheimerFunds, Inc. | 1,867,384 | 154,022,000 | 1.13% | ||
| 18 | TIAA CREF INVESTMENT MANAGEMENT LLC | 1,545,384 | 127,463,000 | 0.94% | ||
| 19 | SECTORAL ASSET MANAGEMENT INC | 1,489,137 | 122,824,000 | 0.90% | ||
| 20 | Bank of New York Mellon Corp | 1,464,429 | 120,786,000 | 0.89% | ||
| 21 | FRANKLIN RESOURCES INC | 1,360,890 | 112,246,000 | 0.83% | ||
| 22 | Palo Alto Investors LP | 1,340,347 | 110,552,000 | 0.81% | ||
| 23 | VICTORY CAPITAL MANAGEMENT INC | 1,340,066 | 110,529,000 | 0.81% | ||
| 24 | DEUTSCHE BANK AG\ | 1,335,264 | 110,128,000 | 0.81% | ||
| 25 | AMERIPRISE FINANCIAL INC | 1,311,159 | 108,144,000 | 0.80% | ||
| 26 | FRED ALGER MANAGEMENT, LLC | 1,239,284 | 102,217,000 | 0.75% | ||
| 27 | TCW GROUP INC | 1,178,390 | 97,194,000 | 0.72% | ||
| 28 | NORTHERN TRUST CORP | 1,165,868 | 96,161,000 | 0.71% | ||
| 29 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,147,639 | 94,658,000 | 0.70% | ||
| 30 | NORGES BANK | 1,110,261 | 91,575,000 | 0.67% | ||
| 31 | BlackRock Group LTD | 1,100,764 | 90,792,000 | 0.67% | ||
| 32 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,052,900 | 86,843,000 | 0.64% | ||
| 33 | BANK OF AMERICA CORP /DE/ | 1,038,437 | 85,651,000 | 0.63% | ||
| 34 | WADDELL & REED FINANCIAL INC | 1,035,795 | 85,432,000 | 0.63% | ||
| 35 | ORBIMED ADVISORS LLC | 1,023,200 | 84,394,000 | 0.62% | ||
| 36 | GEODE CAPITAL MANAGEMENT, LLC | 1,010,910 | 83,334,000 | 0.61% | ||
| 37 | Blue Ridge Capital, L.L.C. | 1,000,000 | 82,480,000 | 0.61% | ||
| 38 | AMERICAN CENTURY COMPANIES INC | 997,098 | 82,241,000 | 0.61% | ||
| 39 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 985,168 | 81,257,000 | 0.60% | ||
| 40 | Amici Capital, LLC | 886,419 | 73,112,000 | 0.54% | ||
| 41 | GOLDMAN SACHS GROUP INC | 844,307 | 69,639,000 | 0.51% | ||
| 42 | Clearbridge Investments, LLC | 635,807 | 52,441,000 | 0.39% | ||
| 43 | Legal & General Group Plc | 633,281 | 52,233,000 | 0.38% | ||
| 44 | Allianz Asset Management GmbH | 612,861 | 50,548,000 | 0.37% | ||
| 45 | VIKING GLOBAL INVESTORS LP | 602,116 | 49,663,000 | 0.37% | ||
| 46 | Tekla Capital Management LLC | 596,145 | 49,170,000 | 0.36% | ||
| 47 | CREDIT SUISSE AG/ | 560,201 | 46,206,000 | 0.34% | ||
| 48 | TEACHERS ADVISORS, LLC | 555,319 | 45,803,000 | 0.34% | ||
| 49 | FIL Ltd | 511,397 | 42,180,000 | 0.31% | ||
| 50 | Senator Investment Group LP | 500,000 | 41,240,000 | 0.30% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
