| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Capital Research Global Investors | 15,853,303 | 1,233,387,000 | 9.80% | ||
| 2 | VANGUARD GROUP INC | 11,448,690 | 890,708,000 | 7.08% | ||
| 3 | FMR LLC | 11,073,345 | 861,507,000 | 6.85% | ||
| 4 | SANDS CAPITAL MANAGEMENT, LLC | 10,918,317 | 849,445,000 | 6.75% | ||
| 5 | JENNISON ASSOCIATES LLC | 9,051,244 | 704,187,000 | 5.60% | ||
| 6 | PRIMECAP MANAGEMENT CO/CA/ | 7,319,319 | 569,443,000 | 4.53% | ||
| 7 | BAKER BROS. ADVISORS LP | 4,806,483 | 373,944,000 | 2.97% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 3,917,865 | 304,810,000 | 2.42% | ||
| 9 | BlackRock Fund Advisors | 3,737,456 | 290,774,000 | 2.31% | ||
| 10 | PRICE T ROWE ASSOCIATES INC /MD/ | 3,525,314 | 274,269,000 | 2.18% | ||
| 11 | Temasek Holdings (Private) Ltd | 3,472,712 | 270,177,000 | 2.15% | ||
| 12 | JPMORGAN CHASE & CO | 3,375,543 | 262,618,000 | 2.09% | ||
| 13 | STATE STREET CORP | 3,349,037 | 260,556,000 | 2.07% | ||
| 14 | WELLS FARGO & COMPANY/MN | 2,504,627 | 194,861,000 | 1.55% | ||
| 15 | Invesco Ltd. | 2,357,862 | 183,441,000 | 1.46% | ||
| 16 | OppenheimerFunds, Inc. | 2,069,013 | 160,969,000 | 1.28% | ||
| 17 | Bank of New York Mellon Corp | 1,810,788 | 140,879,000 | 1.12% | ||
| 18 | Palo Alto Investors LP | 1,737,399 | 135,170,000 | 1.07% | ||
| 19 | CITADEL ADVISORS LLC | 1,653,983 | 128,680,000 | 1.02% | ||
| 20 | ORBIMED ADVISORS LLC | 1,518,500 | 118,139,000 | 0.94% | ||
| 21 | AMERIPRISE FINANCIAL INC | 1,479,745 | 115,122,000 | 0.91% | ||
| 22 | FRED ALGER MANAGEMENT, LLC | 1,435,787 | 111,705,000 | 0.89% | ||
| 23 | TIAA CREF INVESTMENT MANAGEMENT LLC | 1,395,816 | 108,594,000 | 0.86% | ||
| 24 | DEUTSCHE BANK AG\ | 1,378,924 | 107,273,000 | 0.85% | ||
| 25 | FRANKLIN RESOURCES INC | 1,361,996 | 105,962,000 | 0.84% | ||
| 26 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 1,254,176 | 97,575,000 | 0.78% | ||
| 27 | NORTHERN TRUST CORP | 1,210,734 | 94,196,000 | 0.75% | ||
| 28 | TCW GROUP INC | 1,200,418 | 93,392,000 | 0.74% | ||
| 29 | BANK OF AMERICA CORP /DE/ | 1,196,905 | 93,120,000 | 0.74% | ||
| 30 | VICTORY CAPITAL MANAGEMENT INC | 1,184,794 | 92,177,000 | 0.73% | ||
| 31 | Alyeska Investment Group, L.P. | 1,120,212 | 87,152,000 | 0.69% | ||
| 32 | PICTET ASSET MANAGEMENT LTD | 968,295 | 86,808,000 | 0.69% | ||
| 33 | WADDELL & REED FINANCIAL INC | 1,107,505 | 86,164,000 | 0.68% | ||
| 34 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,099,461 | 85,540,000 | 0.68% | ||
| 35 | GEODE CAPITAL MANAGEMENT, LLC | 1,056,429 | 82,153,000 | 0.65% | ||
| 36 | BlackRock Group LTD | 1,023,370 | 79,617,000 | 0.63% | ||
| 37 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,000,000 | 77,800,000 | 0.62% | ||
| 38 | NORGES BANK | 950,838 | 73,976,000 | 0.59% | ||
| 39 | Blue Ridge Capital, L.L.C. | 800,000 | 62,240,000 | 0.49% | ||
| 40 | HealthCor Management, L.P. | 750,000 | 58,350,000 | 0.46% | ||
| 41 | ING GROEP NV | 737,335 | 57,357,000 | 0.46% | ||
| 42 | GOLDMAN SACHS GROUP INC | 690,702 | 53,737,000 | 0.43% | ||
| 43 | AMERICAN CENTURY COMPANIES INC | 689,122 | 53,614,000 | 0.43% | ||
| 44 | Allianz Asset Management GmbH | 668,746 | 52,028,000 | 0.41% | ||
| 45 | Tekla Capital Management LLC | 653,845 | 50,869,000 | 0.40% | ||
| 46 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 650,400 | 50,601,000 | 0.40% | Put | |
| 47 | Senator Investment Group LP | 650,000 | 50,570,000 | 0.40% | ||
| 48 | Clearbridge Investments, LLC | 649,040 | 50,495,000 | 0.40% | ||
| 49 | Legal & General Group Plc | 643,509 | 50,065,000 | 0.40% | ||
| 50 | VOYA INVESTMENT MANAGEMENT LLC | 625,347 | 48,652,000 | 0.39% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
