| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ABIOMED INC | 2,325,959 | 220,524,000 | 17.12% | ||
| 2 | UNITED THERAPEUTICS | 1,525,654 | 170,004,000 | 13.20% | ||
| 3 | Anacor Pharmaceuticals Inc | 2,219,042 | 118,608,000 | 9.21% | ||
| 4 | BIOMARIN | 1,340,347 | 110,552,000 | 8.58% | ||
| 5 | AMAG PHARMACEUTICALS INC COM | 2,906,194 | 68,005,000 | 5.28% | ||
| 6 | CLOVIS ONCOLOGY INC | 3,461,365 | 66,458,000 | 5.16% | ||
| 7 | INSMED INC COM PAR .01 | 4,790,800 | 60,699,000 | 4.71% | ||
| 8 | Wright Medical Group NV | 2,190,957 | 36,370,000 | 2.82% | ||
| 9 | VANDA PHARMACEUTICALS INC COM | 4,030,908 | 33,698,000 | 2.62% | ||
| 10 | EPIZYME INC COM | 2,655,479 | 32,184,000 | 2.50% | ||
| 11 | AMICUS THERAPEUTICS INC | 3,551,173 | 30,007,000 | 2.33% | ||
| 12 | PROTHENA CORP PLC | 695,518 | 28,628,000 | 2.22% | ||
| 13 | GILEAD SCIENCES INC | 302,900 | 27,824,000 | 2.16% | ||
| 14 | KARYOPHARM THERAPEUTICS INC COM | 3,098,145 | 27,635,000 | 2.15% | ||
| 15 | CELGENE CORP | 270,800 | 27,104,000 | 2.10% | ||
| 16 | MEDIVATION INC | 525,462 | 24,161,000 | 1.88% | ||
| 17 | ENDO INTL | 828,630 | 23,326,000 | 1.81% | ||
| 18 | CEMPRA INC | 1,215,833 | 21,301,000 | 1.65% | ||
| 19 | STAAR SURGICAL CO | 2,641,875 | 19,523,000 | 1.52% | ||
| 20 | SHIRE PLC | 106,100 | 18,239,000 | 1.42% | ||
| 21 | ZELTIQ AESTHETICS INCORPORATED | 573,636 | 15,580,000 | 1.21% | ||
| 22 | ARIAD PHARMACEUTICALS INC | 2,248,317 | 14,367,000 | 1.12% | ||
| 23 | SEQUENOM INC | 10,023,842 | 14,134,000 | 1.10% | ||
| 24 | Momenta Pharmaceuticals Inc | 1,468,776 | 13,571,000 | 1.05% | ||
| 25 | ACADIA PHARMACEUTICALS INC COM | 485,100 | 13,563,000 | 1.05% | ||
| 26 | RIGEL PHARMACEUTICAL INC | 5,230,919 | 10,880,000 | 0.84% | ||
| 27 | Heartware International, Inc. | 251,868 | 7,914,000 | 0.61% | ||
| 28 | ALIMERA SCIENCES INC | 3,013,793 | 5,274,000 | 0.41% | ||
| 29 | AIMMUNE THERAPEUTICS INC COM | 325,599 | 4,415,000 | 0.34% | ||
| 30 | ACELRX PHARMACEUTICALS INC | 1,425,439 | 4,390,000 | 0.34% | ||
| 31 | Sunesis Pharmaceuticals I | 6,974,854 | 3,766,000 | 0.29% | ||
| 32 | EXACT SCIENCES CORP | 396,276 | 2,671,000 | 0.21% | ||
| 33 | IDERA PHARMACEUTICALS INC | 1,257,748 | 2,490,000 | 0.19% | ||
| 34 | ALIGN TECHNOLOGY INC | 27,757 | 2,018,000 | 0.16% | ||
| 35 | INTREXON CORP | 47,100 | 1,596,000 | 0.12% | ||
| 36 | Dicerna Pharmaceuticals | 267,890 | 1,436,000 | 0.11% | ||
| 37 | HISTOGENICS CORP | 454,545 | 1,041,000 | 0.08% | ||
| 38 | ALCOBRA LTD | 254,188 | 963,000 | 0.07% | ||
| 39 | Orexigen Therapeutics, Inc. | 1,673,024 | 941,000 | 0.07% | ||
| 40 | CYTOKINETICS INC | 123,686 | 872,000 | 0.07% | ||
| 41 | SOPHIRIS BIO INC | 494,000 | 711,000 | 0.06% | ||
| 42 | MARINUS PHARMACEUTICALS INC | 59,017 | 318,000 | 0.02% | ||
| 43 | ZOGENIX INC | 28,600 | 264,000 | 0.02% | ||
| 44 | UNIQURE NV | 20,453 | 243,000 | 0.02% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001306923-16-000048, filed 2016.05.16).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
