| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | HORIZON PHARMA PLC | 7,053,504 | 183,179,000 | 14.27% | ||
| 2 | FLAMEL TECHNOLOGIES SA SPONSORED ADR | 4,719,959 | 84,865,000 | 6.61% | ||
| 3 | RETROPHIN INC COM | 2,962,298 | 70,977,000 | 5.53% | ||
| 4 | AEGERION PHARMACEUTICALS INC | 2,502,578 | 65,492,000 | 5.10% | ||
| 5 | PROGENICS PHARMACEUTICALS IN | 8,951,169 | 53,528,000 | 4.17% | ||
| 6 | EMERGENT BIOSOLUTIONS INC COM | 1,810,519 | 52,071,000 | 4.06% | ||
| 7 | ANGIODYNAMICS INC | 2,398,527 | 42,670,000 | 3.32% | ||
| 8 | HERON THERAPEUTICS INC | 2,808,173 | 40,859,000 | 3.18% | ||
| 9 | AMPHASTAR PHARMACEUTICALS IN COM | 2,127,854 | 31,833,000 | 2.48% | ||
| 10 | RIGEL PHARMACEUTICAL INC | 8,246,329 | 29,439,000 | 2.29% | ||
| 11 | BioDelivery Sciences International Inc | 2,246,399 | 23,587,000 | 1.84% | ||
| 12 | PERNIX THERAPEUTICS HLDGS IN | 2,168,326 | 23,179,000 | 1.81% | ||
| 13 | ALERE INC | 452,423 | 22,123,000 | 1.72% | ||
| 14 | IDERA PHARMACEUTICALS INC | 5,663,845 | 21,013,000 | 1.64% | ||
| 15 | ARATANA THERAPEUTICS INC COM | 1,131,865 | 18,121,000 | 1.41% | ||
| 16 | DERMA SCIENCES INC COM PAR .01 | 2,130,477 | 18,045,000 | 1.41% | ||
| 17 | CATALYST PHARMACEUTICALS INC | 4,083,177 | 17,680,000 | 1.38% | ||
| 18 | IGNYTA INC COM | 1,741,700 | 17,330,000 | 1.35% | ||
| 19 | DYNAVAX TECHNOLOGIES CORP | 766,010 | 17,182,000 | 1.34% | ||
| 20 | DEPOMED INC | 705,204 | 15,804,000 | 1.23% | ||
| 21 | ZOGENIX INC | 10,737,645 | 14,711,000 | 1.15% | ||
| 22 | HORIZON PHARMA PLC | 500,000 | 12,985,000 | 1.01% | Call | |
| 23 | LA JOLLA PHARMACEUTICAL CO | 703,470 | 12,874,000 | 1.00% | ||
| 24 | Lion Biotechnologies | 1,062,419 | 12,866,000 | 1.00% | ||
| 25 | SOCIETAL CDMO INC | 1,413,533 | 12,821,000 | 1.00% | ||
| 26 | ANTARES PHARMA INC | 4,700,000 | 12,737,000 | 0.99% | ||
| 27 | SYNERON MEDICAL LTD ORD SHS | 1,005,221 | 12,445,000 | 0.97% | ||
| 28 | GENOCEA BIOSCIENCES INC | 1,035,000 | 12,275,000 | 0.96% | ||
| 29 | UNIVERSAL AMERN CORP NEW | 1,133,989 | 12,111,000 | 0.94% | ||
| 30 | ADVAXIS INC COM NEW | 805,994 | 11,639,000 | 0.91% | ||
| 31 | CORIUM INTERNATIONAL INC | 1,736,736 | 11,376,000 | 0.89% | ||
| 32 | RETROPHIN INC COM | 500,000 | 11,198,000 | 0.87% | Call | |
| 33 | ATRICURE INC | 533,354 | 10,928,000 | 0.85% | ||
| 34 | ANTHERA PHARMACEUTICALS I | 2,420,457 | 10,819,000 | 0.84% | ||
| 35 | VERASTEM INC COM | 1,050,000 | 10,679,000 | 0.83% | ||
| 36 | Anacor Pharmaceuticals Inc | 184,320 | 10,663,000 | 0.83% | ||
| 37 | DISCOVERY LABORATORIES INC N | 8,072,500 | 9,606,000 | 0.75% | ||
| 38 | ADMA BIOLOGICS, INC. | 964,193 | 9,449,000 | 0.74% | ||
| 39 | TREVENA INC | 1,409,153 | 9,188,000 | 0.72% | ||
| 40 | MIRATI THERAPEUTICS INC COM | 306,463 | 8,985,000 | 0.70% | ||
| 41 | ALCOBRA LTD | 1,556,016 | 8,760,000 | 0.68% | ||
| 42 | ELEVEN BIOTHERAPEUTICS INC | 966,057 | 8,617,000 | 0.67% | ||
| 43 | MEDGENICS INC | 1,025,000 | 8,262,000 | 0.64% | ||
| 44 | IGI LABS INC | 1,000,000 | 8,160,000 | 0.64% | ||
| 45 | PARATEK PHARMACEUTICALS INC | 260,283 | 8,136,000 | 0.63% | ||
| 46 | FLEXION THERAPEUTICS INC COM | 348,204 | 7,842,000 | 0.61% | ||
| 47 | DURECT CORP | 3,904,495 | 7,458,000 | 0.58% | ||
| 48 | TONIX PHARMACEUTICALS HLD | 1,176,639 | 7,436,000 | 0.58% | ||
| 49 | Redhill Biopharma Ltd | 484,281 | 7,046,000 | 0.55% | ||
| 50 | EPIRUS BIOPHARMA | 775,000 | 6,936,000 | 0.54% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0000919574-15-004356, filed 2015.05.15).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
