| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Capital World Investors | 3,002,044 | 96,155,000 | 8.09% | ||
| 2 | LORD, ABBETT & CO. LLC | 2,833,377 | 90,753,000 | 7.64% | ||
| 3 | FMR LLC | 2,785,000 | 89,203,000 | 7.51% | ||
| 4 | Aisling Capital LLC | 2,603,528 | 83,391,000 | 7.02% | ||
| 5 | EAGLE ASSET MANAGEMENT INC | 1,613,564 | 51,682,000 | 4.35% | ||
| 6 | Point72 Asset Management, L.P. | 1,441,750 | 46,179,000 | 3.89% | ||
| 7 | Visium Asset Management, LP | 1,254,286 | 40,175,000 | 3.38% | ||
| 8 | RS INVESTMENT MANAGEMENT CO LLC | 1,242,306 | 39,791,000 | 3.35% | ||
| 9 | VANGUARD GROUP INC | 1,089,022 | 34,881,000 | 2.94% | ||
| 10 | RIVERBRIDGE PARTNERS LLC | 1,078,680 | 34,550,000 | 2.91% | ||
| 11 | Granahan Investment Management, LLC | 916,092 | 29,342,000 | 2.47% | ||
| 12 | MILLENNIUM MANAGEMENT LLC | 901,276 | 28,868,000 | 2.43% | ||
| 13 | PointState Capital LP | 844,700 | 27,056,000 | 2.28% | ||
| 14 | BlackRock Fund Advisors | 844,541 | 27,051,000 | 2.28% | ||
| 15 | BlackRock Institutional Trust Company, N.A. | 806,044 | 25,818,000 | 2.17% | ||
| 16 | DEUTSCHE BANK AG\ | 603,567 | 19,330,000 | 1.63% | ||
| 17 | STATE STREET CORP | 598,701 | 19,177,000 | 1.61% | ||
| 18 | Palo Alto Investors LP | 568,436 | 18,207,000 | 1.53% | ||
| 19 | NORTHERN TRUST CORP | 536,669 | 17,189,000 | 1.45% | ||
| 20 | FULLER & THALER ASSET MANAGEMENT, INC. | 533,697 | 17,094,000 | 1.44% | ||
| 21 | BLAIR WILLIAM & CO/IL | 470,983 | 15,085,000 | 1.27% | ||
| 22 | PFM Health Sciences, LP | 445,686 | 14,275,000 | 1.20% | ||
| 23 | Cupps Capital Management, LLC | 421,630 | 13,504,000 | 1.14% | ||
| 24 | DEERFIELD MANAGEMENT COMPANY, L.P. | 420,063 | 13,455,000 | 1.13% | ||
| 25 | MIG Capital, LLC | 402,814 | 12,902,000 | 1.09% | ||
| 26 | NEXT CENTURY GROWTH INVESTORS LLC | 397,303 | 12,725,000 | 1.07% | ||
| 27 | EverPoint Asset Management, LLC | 350,000 | 11,211,000 | 0.94% | ||
| 28 | COLUMBIA PARTNERS L.L.C. INVESTMENT MANAGEMENT | 334,464 | 10,712,000 | 0.90% | ||
| 29 | COLUMBUS CIRCLE INVESTORS | 321,488 | 10,297,000 | 0.87% | ||
| 30 | AXA S.A. | 316,000 | 10,121,000 | 0.85% | ||
| 31 | HighTower Advisors, LLC | 312,676 | 10,014,000 | 0.84% | ||
| 32 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 270,469 | 8,663,000 | 0.73% | ||
| 33 | Bank of New York Mellon Corp | 260,490 | 8,342,000 | 0.70% | ||
| 34 | QS Investors, LLC | 254,269 | 8,144,000 | 0.69% | ||
| 35 | Nichols Asset Management LLC | 252,260 | 8,080,000 | 0.68% | ||
| 36 | Ghost Tree Capital, LLC | 235,000 | 7,527,000 | 0.63% | ||
| 37 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 220,329 | 7,057,000 | 0.59% | ||
| 38 | MARSHALL WACE, LLP | 217,859 | 6,978,000 | 0.59% | ||
| 39 | CITADEL ADVISORS LLC | 213,865 | 6,850,000 | 0.58% | ||
| 40 | Pier Capital, LLC | 199,397 | 6,387,000 | 0.54% | ||
| 41 | GEODE CAPITAL MANAGEMENT, LLC | 191,708 | 6,140,000 | 0.52% | ||
| 42 | TWO SIGMA INVESTMENTS, LP | 188,031 | 6,023,000 | 0.51% | ||
| 43 | FIL Ltd | 173,380 | 5,553,000 | 0.47% | ||
| 44 | TWO SIGMA ADVISERS, LP | 159,582 | 5,116,000 | 0.43% | ||
| 45 | BANK OF AMERICA CORP /DE/ | 159,649 | 5,113,000 | 0.43% | ||
| 46 | Rhenman & Partners Asset Management AB | 157,000 | 5,029,000 | 0.42% | ||
| 47 | Invesco Ltd. | 144,927 | 4,642,000 | 0.39% | ||
| 48 | MORGAN STANLEY | 138,713 | 4,444,000 | 0.37% | ||
| 49 | Nuveen Asset Management, LLC | 118,358 | 3,791,000 | 0.32% | ||
| 50 | GOLDMAN SACHS GROUP INC | 110,500 | 3,539,000 | 0.30% | Call |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
