| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 5,942,039 | 233,047,000 | 13.35% | ||
| 2 | Capital World Investors | 3,122,044 | 122,447,000 | 7.02% | ||
| 3 | BlackRock Fund Advisors | 2,579,423 | 101,165,000 | 5.80% | ||
| 4 | LORD, ABBETT & CO. LLC | 2,514,376 | 98,613,000 | 5.65% | ||
| 5 | VANGUARD GROUP INC | 1,687,578 | 66,187,000 | 3.79% | ||
| 6 | Aisling Capital LLC | 1,609,727 | 63,133,000 | 3.62% | ||
| 7 | ALLIANCEBERNSTEIN L.P. | 1,476,611 | 57,913,000 | 3.32% | ||
| 8 | EAGLE ASSET MANAGEMENT INC | 1,446,229 | 56,721,000 | 3.25% | ||
| 9 | RIVERBRIDGE PARTNERS LLC | 1,432,492 | 56,182,000 | 3.22% | ||
| 10 | Palo Alto Investors LP | 1,414,563 | 55,479,000 | 3.18% | ||
| 11 | Granahan Investment Management, LLC | 1,235,543 | 48,458,000 | 2.78% | ||
| 12 | BlackRock Institutional Trust Company, N.A. | 873,544 | 34,260,000 | 1.96% | ||
| 13 | VICTORY CAPITAL MANAGEMENT INC | 818,164 | 32,088,000 | 1.84% | ||
| 14 | 12 West Capital Management LP | 800,229 | 31,385,000 | 1.80% | ||
| 15 | Point72 Asset Management, L.P. | 797,696 | 31,286,000 | 1.79% | ||
| 16 | MILLENNIUM MANAGEMENT LLC | 766,066 | 30,045,000 | 1.72% | ||
| 17 | STATE STREET CORP | 749,351 | 29,394,000 | 1.68% | ||
| 18 | NEXT CENTURY GROWTH INVESTORS LLC | 712,817 | 27,956,000 | 1.60% | ||
| 19 | WELLS FARGO & COMPANY/MN | 705,426 | 27,667,000 | 1.59% | ||
| 20 | SAMLYN CAPITAL, LLC | 651,700 | 25,560,000 | 1.46% | ||
| 21 | NORTHERN TRUST CORP | 636,401 | 24,960,000 | 1.43% | ||
| 22 | Bank of New York Mellon Corp | 457,383 | 17,938,000 | 1.03% | ||
| 23 | PFM Health Sciences, LP | 455,586 | 17,868,000 | 1.02% | ||
| 24 | Provident Investment Management, Inc. | 416,794 | 16,347,000 | 0.94% | ||
| 25 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 412,602 | 16,182,000 | 0.93% | ||
| 26 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 396,607 | 15,555,000 | 0.89% | ||
| 27 | FULLER & THALER ASSET MANAGEMENT, INC. | 381,497 | 14,962,000 | 0.86% | ||
| 28 | HANDELSBANKEN FONDER AB | 369,100 | 14,476,000 | 0.83% | ||
| 29 | AMERIPRISE FINANCIAL INC | 352,084 | 13,809,000 | 0.79% | ||
| 30 | OppenheimerFunds, Inc. | 333,845 | 13,093,000 | 0.75% | ||
| 31 | HighTower Advisors, LLC | 324,951 | 12,745,000 | 0.73% | ||
| 32 | COLUMBIA PARTNERS L.L.C. INVESTMENT MANAGEMENT | 302,572 | 11,866,000 | 0.68% | ||
| 33 | JENNISON ASSOCIATES LLC | 300,315 | 11,778,000 | 0.67% | ||
| 34 | Elk Creek Partners, LLC | 295,188 | 11,577,000 | 0.66% | ||
| 35 | ZEVENBERGEN CAPITAL INVESTMENTS LLC | 283,860 | 11,133,000 | 0.64% | ||
| 36 | PRINCIPAL FINANCIAL GROUP INC | 258,021 | 10,120,000 | 0.58% | ||
| 37 | AXA S.A. | 254,000 | 9,962,000 | 0.57% | ||
| 38 | CASTLEARK MANAGEMENT LLC | 245,550 | 9,630,000 | 0.55% | ||
| 39 | GEODE CAPITAL MANAGEMENT, LLC | 244,326 | 9,582,000 | 0.55% | ||
| 40 | CREDIT SUISSE AG/ | 228,645 | 8,968,000 | 0.51% | ||
| 41 | TWO SIGMA INVESTMENTS, LP | 224,883 | 8,820,000 | 0.51% | ||
| 42 | Cortina Asset Management, LLC | 208,613 | 8,182,000 | 0.47% | ||
| 43 | FRONTIER CAPITAL MANAGEMENT CO LLC | 207,280 | 8,130,000 | 0.47% | ||
| 44 | State of New Jersey Common Pension Fund D | 200,000 | 7,844,000 | 0.45% | ||
| 45 | RENAISSANCE TECHNOLOGIES LLC | 161,600 | 6,338,000 | 0.36% | ||
| 46 | Rhenman & Partners Asset Management AB | 160,000 | 6,275,200 | 0.36% | ||
| 47 | BANK OF AMERICA CORP /DE/ | 152,375 | 5,976,000 | 0.34% | ||
| 48 | BlackRock Investment Management, LLC | 149,232 | 5,853,000 | 0.34% | ||
| 49 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 146,599 | 5,750,000 | 0.33% | ||
| 50 | DRIEHAUS CAPITAL MANAGEMENT LLC | 141,163 | 5,536,000 | 0.32% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
