| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 4,277,811 | 116,913,000 | 9.57% | ||
| 2 | Capital World Investors | 3,122,044 | 85,325,000 | 6.98% | ||
| 3 | BlackRock Fund Advisors | 2,297,982 | 62,804,000 | 5.14% | ||
| 4 | Point72 Asset Management, L.P. | 2,219,762 | 60,666,000 | 4.97% | ||
| 5 | Aisling Capital LLC | 2,109,727 | 57,659,000 | 4.72% | ||
| 6 | VANGUARD GROUP INC | 1,569,585 | 42,897,000 | 3.51% | ||
| 7 | EAGLE ASSET MANAGEMENT INC | 1,472,716 | 40,249,000 | 3.29% | ||
| 8 | Palo Alto Investors LP | 1,391,079 | 38,018,000 | 3.11% | ||
| 9 | LORD, ABBETT & CO. LLC | 1,386,951 | 37,906,000 | 3.10% | ||
| 10 | NEXT CENTURY GROWTH INVESTORS LLC | 1,320,983 | 36,102,000 | 2.95% | ||
| 11 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,297,000 | 35,447,000 | 2.90% | ||
| 12 | SAMLYN CAPITAL, LLC | 1,175,352 | 32,122,000 | 2.63% | ||
| 13 | RIVERBRIDGE PARTNERS LLC | 1,166,362 | 31,877,000 | 2.61% | ||
| 14 | ALLIANCEBERNSTEIN L.P. | 1,164,819 | 31,835,000 | 2.61% | ||
| 15 | Granahan Investment Management, LLC | 1,161,163 | 31,735,000 | 2.60% | ||
| 16 | RS INVESTMENT MANAGEMENT CO LLC | 1,056,821 | 28,883,000 | 2.36% | ||
| 17 | MILLENNIUM MANAGEMENT LLC | 958,442 | 26,194,000 | 2.14% | ||
| 18 | BlackRock Institutional Trust Company, N.A. | 864,437 | 23,625,000 | 1.93% | ||
| 19 | WELLS FARGO & COMPANY/MN | 751,061 | 20,526,000 | 1.68% | ||
| 20 | Calamos Advisors LLC | 696,038 | 19,023,000 | 1.56% | ||
| 21 | STATE STREET CORP | 679,450 | 18,569,000 | 1.52% | ||
| 22 | NORTHERN TRUST CORP | 606,432 | 16,573,000 | 1.36% | ||
| 23 | PFM Health Sciences, LP | 604,342 | 16,517,000 | 1.35% | ||
| 24 | 12 West Capital Management LP | 590,790 | 16,146,000 | 1.32% | ||
| 25 | EverPoint Asset Management, LLC | 550,000 | 15,032,000 | 1.23% | ||
| 26 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 533,203 | 14,572,000 | 1.19% | ||
| 27 | COLUMBIA PARTNERS L.L.C. INVESTMENT MANAGEMENT | 462,951 | 12,652,000 | 1.04% | ||
| 28 | FULLER & THALER ASSET MANAGEMENT, INC. | 421,597 | 11,522,000 | 0.94% | ||
| 29 | Provident Investment Management, Inc. | 420,046 | 11,480,000 | 0.94% | ||
| 30 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 405,336 | 11,078,000 | 0.91% | ||
| 31 | Elk Creek Partners, LLC | 393,866 | 10,764,000 | 0.88% | ||
| 32 | Bank of New York Mellon Corp | 386,392 | 10,560,000 | 0.86% | ||
| 33 | AXA S.A. | 360,000 | 9,839,000 | 0.81% | ||
| 34 | HighTower Advisors, LLC | 332,234 | 9,079,000 | 0.74% | ||
| 35 | AMERIPRISE FINANCIAL INC | 316,704 | 8,656,000 | 0.71% | ||
| 36 | QS Investors, LLC | 245,682 | 6,714,000 | 0.55% | ||
| 37 | State of New Jersey Common Pension Fund D | 240,000 | 6,559,000 | 0.54% | ||
| 38 | GEODE CAPITAL MANAGEMENT, LLC | 233,760 | 6,388,000 | 0.52% | ||
| 39 | DRILL CRAIG A | 230,200 | 6,291,000 | 0.51% | ||
| 40 | PRINCIPAL FINANCIAL GROUP INC | 227,664 | 6,222,000 | 0.51% | ||
| 41 | PRICE T ROWE ASSOCIATES INC /MD/ | 223,359 | 6,104,000 | 0.50% | ||
| 42 | HANDELSBANKEN FONDER AB | 205,000 | 5,603,000 | 0.46% | ||
| 43 | EMERALD ACQUISITION LTD. | 170,664 | 4,664,000 | 0.38% | ||
| 44 | Rhenman & Partners Asset Management AB | 160,000 | 4,373,000 | 0.36% | ||
| 45 | BANK OF AMERICA CORP /DE/ | 154,647 | 4,227,000 | 0.35% | ||
| 46 | BlackRock Investment Management, LLC | 146,379 | 4,001,000 | 0.33% | ||
| 47 | MORGAN STANLEY | 137,821 | 3,767,000 | 0.31% | ||
| 48 | C WorldWide Group Holding A/S | 135,000 | 3,690,000 | 0.30% | ||
| 49 | PUTNAM INVESTMENTS LLC | 130,857 | 3,576,000 | 0.29% | ||
| 50 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 128,699 | 3,517,000 | 0.29% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
