| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Capital World Investors | 3,122,044 | 84,795,000 | 7.21% | ||
| 2 | FMR LLC | 2,945,682 | 80,005,000 | 6.80% | ||
| 3 | Visium Asset Management, LP | 2,871,762 | 77,997,000 | 6.63% | ||
| 4 | Aisling Capital LLC | 2,103,528 | 57,132,000 | 4.86% | ||
| 5 | BlackRock Fund Advisors | 2,098,036 | 56,983,000 | 4.85% | ||
| 6 | Point72 Asset Management, L.P. | 1,698,300 | 46,126,000 | 3.92% | ||
| 7 | EAGLE ASSET MANAGEMENT INC | 1,560,987 | 42,396,000 | 3.60% | ||
| 8 | VANGUARD GROUP INC | 1,507,885 | 40,954,000 | 3.48% | ||
| 9 | MILLENNIUM MANAGEMENT LLC | 1,343,064 | 36,478,000 | 3.10% | ||
| 10 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,104,417 | 29,996,000 | 2.55% | ||
| 11 | LORD, ABBETT & CO. LLC | 1,084,098 | 29,444,000 | 2.50% | ||
| 12 | SAMLYN CAPITAL, LLC | 1,071,444 | 29,100,000 | 2.47% | ||
| 13 | NEXT CENTURY GROWTH INVESTORS LLC | 1,043,924 | 28,352,000 | 2.41% | ||
| 14 | RIVERBRIDGE PARTNERS LLC | 1,021,581 | 27,746,000 | 2.36% | ||
| 15 | Granahan Investment Management, LLC | 986,133 | 26,783,000 | 2.28% | ||
| 16 | PFM Health Sciences, LP | 898,129 | 24,393,000 | 2.07% | ||
| 17 | BlackRock Institutional Trust Company, N.A. | 840,472 | 22,827,000 | 1.94% | ||
| 18 | RS INVESTMENT MANAGEMENT CO LLC | 781,322 | 21,221,000 | 1.80% | ||
| 19 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 726,246 | 19,725,000 | 1.68% | ||
| 20 | WELLS FARGO & COMPANY/MN | 689,598 | 18,730,000 | 1.59% | ||
| 21 | STATE STREET CORP | 655,971 | 17,816,000 | 1.51% | ||
| 22 | DEUTSCHE BANK AG\ | 634,751 | 17,239,000 | 1.47% | ||
| 23 | RENAISSANCE TECHNOLOGIES LLC | 594,400 | 16,144,000 | 1.37% | ||
| 24 | Palo Alto Investors LP | 573,636 | 15,580,000 | 1.32% | ||
| 25 | COLUMBIA PARTNERS L.L.C. INVESTMENT MANAGEMENT | 572,895 | 15,559,000 | 1.32% | ||
| 26 | NORTHERN TRUST CORP | 551,167 | 14,970,000 | 1.27% | ||
| 27 | Provident Investment Management, Inc. | 454,031 | 12,331,000 | 1.05% | ||
| 28 | Bank of New York Mellon Corp | 428,344 | 11,634,000 | 0.99% | ||
| 29 | FULLER & THALER ASSET MANAGEMENT, INC. | 423,397 | 11,499,000 | 0.98% | ||
| 30 | AXA S.A. | 378,000 | 10,266,000 | 0.87% | ||
| 31 | AMERIPRISE FINANCIAL INC | 333,518 | 9,058,000 | 0.77% | ||
| 32 | Nichols Asset Management LLC | 327,661 | 8,899,000 | 0.76% | ||
| 33 | Elk Creek Partners, LLC | 309,551 | 8,407,000 | 0.71% | ||
| 34 | HighTower Advisors, LLC | 302,467 | 8,215,000 | 0.70% | ||
| 35 | DRILL CRAIG A | 285,800 | 7,762,000 | 0.66% | ||
| 36 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 268,932 | 7,304,000 | 0.62% | ||
| 37 | CITADEL ADVISORS LLC | 250,320 | 6,798,000 | 0.58% | ||
| 38 | QS Investors, LLC | 247,889 | 6,733,000 | 0.57% | ||
| 39 | Pier Capital, LLC | 228,992 | 6,219,000 | 0.53% | ||
| 40 | PRICE T ROWE ASSOCIATES INC /MD/ | 223,359 | 6,066,000 | 0.52% | ||
| 41 | PRINCIPAL FINANCIAL GROUP INC | 219,163 | 5,952,000 | 0.51% | ||
| 42 | GEODE CAPITAL MANAGEMENT, LLC | 216,561 | 5,881,000 | 0.50% | ||
| 43 | Polar Capital LLP | 200,000 | 5,432,000 | 0.46% | ||
| 44 | HIGHLAND CAPITAL MANAGEMENT LP | 164,448 | 4,466,000 | 0.38% | ||
| 45 | BANK OF AMERICA CORP /DE/ | 161,400 | 4,383,000 | 0.37% | ||
| 46 | Rhenman & Partners Asset Management AB | 160,000 | 4,346,000 | 0.37% | ||
| 47 | C WorldWide Group Holding A/S | 150,000 | 4,074,000 | 0.35% | ||
| 48 | MORGAN STANLEY | 142,575 | 3,872,000 | 0.33% | ||
| 49 | TWO SIGMA INVESTMENTS, LP | 130,811 | 3,553,000 | 0.30% | ||
| 50 | State of Tennessee, Department of Treasury | 125,706 | 3,414,000 | 0.29% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
