| 1 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
3,264,588 |
41,428,000 |
20.48% |
|
|
| 2 |
WELLINGTON MANAGEMENT GROUP LLP |
2,351,333 |
29,839,000 |
14.75% |
|
|
| 3 |
ORBIMED ADVISORS LLC |
1,300,000 |
16,497,000 |
8.16% |
|
|
| 4 |
BlackRock Fund Advisors |
1,085,371 |
13,773,000 |
6.81% |
|
|
| 5 |
VANGUARD GROUP INC |
759,662 |
9,640,000 |
4.77% |
|
|
| 6 |
Epoch Investment Partners, Inc. |
675,088 |
8,567,000 |
4.24% |
|
|
| 7 |
TIVERTON ASSET MANAGEMENT LLC |
550,000 |
6,980,000 |
3.45% |
|
|
| 8 |
BlackRock Institutional Trust Company, N.A. |
488,515 |
6,199,000 |
3.07% |
|
|
| 9 |
ROYCE & ASSOCIATES LP |
481,300 |
6,108,000 |
3.02% |
|
|
| 10 |
DESTRIER CAPITAL MANAGEMENT LLC |
448,494 |
5,691,000 |
2.81% |
|
|
| 11 |
CANNELL CAPITAL LLC |
433,882 |
5,506,000 |
2.72% |
|
|
| 12 |
DIMENSIONAL FUND ADVISORS LP |
372,651 |
4,729,000 |
2.34% |
|
|
| 13 |
STATE STREET CORP |
341,691 |
4,336,000 |
2.14% |
|
|
| 14 |
FULLER & THALER ASSET MANAGEMENT, INC. |
339,741 |
4,311,000 |
2.13% |
|
|
| 15 |
NORTHERN TRUST CORP |
208,771 |
2,650,000 |
1.31% |
|
|
| 16 |
Simcoe Capital Management, LLC |
206,475 |
2,620,000 |
1.30% |
|
|
| 17 |
MORGAN STANLEY |
198,708 |
2,522,000 |
1.25% |
|
|
| 18 |
Bank of New York Mellon Corp |
135,020 |
1,713,000 |
0.85% |
|
|
| 19 |
GEODE CAPITAL MANAGEMENT, LLC |
118,583 |
1,504,000 |
0.74% |
|
|
| 20 |
DEUTSCHE BANK AG\ |
117,398 |
1,489,000 |
0.74% |
|
|
| 21 |
CONTINENTAL ADVISORS LLC |
114,388 |
1,452,000 |
0.72% |
|
|
| 22 |
CITADEL ADVISORS LLC |
114,394 |
1,451,000 |
0.72% |
|
|
| 23 |
PRINCIPAL FINANCIAL GROUP INC |
109,093 |
1,384,000 |
0.68% |
|
|
| 24 |
RENAISSANCE TECHNOLOGIES LLC |
107,400 |
1,363,000 |
0.67% |
|
|
| 25 |
Spark Investment Management LLC |
101,600 |
1,287,000 |
0.64% |
|
|
| 26 |
BOGLE INVESTMENT MANAGEMENT L P /DE/ |
87,525 |
1,110,000 |
0.55% |
|
|
| 27 |
AMERIPRISE FINANCIAL INC |
83,578 |
1,060,000 |
0.52% |
|
|
| 28 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
82,300 |
1,044,000 |
0.52% |
|
|
| 29 |
PARAMETRIC PORTFOLIO ASSOCIATES LLC |
75,547 |
959,000 |
0.47% |
|
|
| 30 |
BlackRock Investment Management, LLC |
72,395 |
919,000 |
0.45% |
|
|
| 31 |
Nationwide Fund Advisors |
68,130 |
865,000 |
0.43% |
|
|
| 32 |
CREDIT SUISSE AG/ |
63,103 |
801,000 |
0.40% |
|
|
| 33 |
NEW YORK STATE TEACHERS RETIREMENT SYSTEM |
59,581 |
756,000 |
0.37% |
|
|
| 34 |
OXFORD ASSET MANAGEMENT LLP |
54,729 |
695,000 |
0.34% |
|
|
| 35 |
GOLDMAN SACHS GROUP INC |
54,642 |
693,000 |
0.34% |
|
|
| 36 |
A.R.T. Advisors, LLC |
51,053 |
647,000 |
0.32% |
|
|
| 37 |
Cowen Prime Services LLC |
43,400 |
551,000 |
0.27% |
|
|
| 38 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
41,553 |
528,000 |
0.26% |
|
|
| 39 |
PRUDENTIAL FINANCIAL INC |
39,725 |
504,000 |
0.25% |
|
|
| 40 |
NEW YORK STATE COMMON RETIREMENT FUND |
39,721 |
504,000 |
0.25% |
|
|
| 41 |
Invesco Ltd. |
39,244 |
498,000 |
0.25% |
|
|
| 42 |
COMERICA BANK |
35,870 |
456,000 |
0.23% |
|
|
| 43 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
32,708 |
415,000 |
0.21% |
|
|
| 44 |
D. E. Shaw & Co., Inc. |
30,866 |
392,000 |
0.19% |
|
|
| 45 |
PUBLIC SECTOR PENSION INVESTMENT BOARD |
27,397 |
348,000 |
0.17% |
|
|
| 46 |
MILLENNIUM MANAGEMENT LLC |
26,895 |
341,000 |
0.17% |
|
|
| 47 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
22,600 |
287,000 |
0.14% |
|
|
| 48 |
COWEN INC. |
20,619 |
262,000 |
0.13% |
|
|
| 49 |
BANK OF AMERICA CORP /DE/ |
19,015 |
241,000 |
0.12% |
|
|
| 50 |
RHUMBLINE ADVISERS |
18,334 |
233,000 |
0.12% |
|
|
