| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. | 3,264,588 | 32,581,000 | 20.51% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 2,182,289 | 21,780,000 | 13.71% | ||
| 3 | ORBIMED ADVISORS LLC | 1,300,000 | 12,974,000 | 8.17% | ||
| 4 | BlackRock Fund Advisors | 1,127,077 | 11,248,000 | 7.08% | ||
| 5 | VANGUARD GROUP INC | 781,786 | 7,802,000 | 4.91% | ||
| 6 | ROYCE & ASSOCIATES LP | 694,500 | 6,931,000 | 4.36% | ||
| 7 | BlackRock Institutional Trust Company, N.A. | 484,753 | 4,838,000 | 3.04% | ||
| 8 | CANNELL CAPITAL LLC | 484,539 | 4,836,000 | 3.04% | ||
| 9 | MORGAN STANLEY | 428,152 | 4,272,000 | 2.69% | ||
| 10 | DIMENSIONAL FUND ADVISORS LP | 385,642 | 3,849,000 | 2.42% | ||
| 11 | FULLER & THALER ASSET MANAGEMENT, INC. | 357,241 | 3,565,000 | 2.24% | ||
| 12 | DESTRIER CAPITAL MANAGEMENT LLC | 350,894 | 3,502,000 | 2.20% | ||
| 13 | MILLENNIUM MANAGEMENT LLC | 347,446 | 3,468,000 | 2.18% | ||
| 14 | STATE STREET CORP | 336,301 | 3,359,000 | 2.11% | ||
| 15 | NORTHERN TRUST CORP | 281,010 | 2,805,000 | 1.77% | ||
| 16 | RENAISSANCE TECHNOLOGIES LLC | 274,500 | 2,740,000 | 1.72% | ||
| 17 | JPMORGAN CHASE & CO | 235,750 | 2,353,000 | 1.48% | ||
| 18 | OXFORD ASSET MANAGEMENT LLP | 221,221 | 2,205,000 | 1.39% | ||
| 19 | Bank of New York Mellon Corp | 160,420 | 1,601,000 | 1.01% | ||
| 20 | Spark Investment Management LLC | 143,700 | 1,434,000 | 0.90% | ||
| 21 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 132,678 | 1,324,000 | 0.83% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 130,631 | 1,302,000 | 0.82% | ||
| 23 | Granite Investment Partners, LLC | 124,296 | 1,241,000 | 0.78% | ||
| 24 | PRINCIPAL FINANCIAL GROUP INC | 109,706 | 1,095,000 | 0.69% | ||
| 25 | CONTINENTAL ADVISORS LLC | 104,488 | 1,043,000 | 0.66% | ||
| 26 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 100,600 | 1,004,000 | 0.63% | ||
| 27 | Glacier Peak Capital LLC | 98,561 | 984,000 | 0.62% | ||
| 28 | TFS CAPITAL LLC | 86,124 | 860,000 | 0.54% | ||
| 29 | AMERIPRISE FINANCIAL INC | 75,423 | 753,000 | 0.47% | ||
| 30 | TWO SIGMA INVESTMENTS, LP | 69,312 | 692,000 | 0.44% | ||
| 31 | BlackRock Investment Management, LLC | 69,208 | 691,000 | 0.43% | ||
| 32 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 62,196 | 620,000 | 0.39% | ||
| 33 | NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 59,525 | 594,000 | 0.37% | ||
| 34 | PEAK6 Group LLC | 55,400 | 553,000 | 0.35% | Put | |
| 35 | NORGES BANK | 55,000 | 549,000 | 0.35% | ||
| 36 | Invesco Ltd. | 48,910 | 488,000 | 0.31% | ||
| 37 | DEUTSCHE BANK AG\ | 45,413 | 451,000 | 0.28% | ||
| 38 | FIRST TRUST ADVISORS LP | 44,952 | 449,000 | 0.28% | ||
| 39 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 44,144 | 441,000 | 0.28% | ||
| 40 | TIAA CREF INVESTMENT MANAGEMENT LLC | 43,364 | 433,000 | 0.27% | ||
| 41 | A.R.T. Advisors, LLC | 40,375 | 402,000 | 0.25% | ||
| 42 | PRUDENTIAL FINANCIAL INC | 38,225 | 381,000 | 0.24% | ||
| 43 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 33,226 | 332,000 | 0.21% | ||
| 44 | Dynamic Technology Lab Private Ltd | 24,599 | 245,000 | 0.15% | ||
| 45 | NEW YORK STATE COMMON RETIREMENT FUND | 22,300 | 223,000 | 0.14% | ||
| 46 | TWO SIGMA ADVISERS, LP | 20,706 | 207,000 | 0.13% | ||
| 47 | RHUMBLINE ADVISERS | 20,704 | 207,000 | 0.13% | ||
| 48 | GSA CAPITAL PARTNERS LLP | 19,502 | 195,000 | 0.12% | ||
| 49 | ALGERT GLOBAL LLC | 19,459 | 194,000 | 0.12% | ||
| 50 | TEACHERS ADVISORS, LLC | 18,842 | 188,000 | 0.12% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
