| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | DEERFIELD MANAGEMENT COMPANY, L.P. | 3,264,588 | 41,819,000 | 20.32% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 2,032,283 | 26,034,000 | 12.65% | ||
| 3 | ORBIMED ADVISORS LLC | 1,300,000 | 16,653,000 | 8.09% | ||
| 4 | BlackRock Fund Advisors | 1,066,158 | 13,657,000 | 6.64% | ||
| 5 | VANGUARD GROUP INC | 783,055 | 10,031,000 | 4.88% | ||
| 6 | MORGAN STANLEY | 735,383 | 9,420,000 | 4.58% | ||
| 7 | ROYCE & ASSOCIATES LP | 581,700 | 7,452,000 | 3.62% | ||
| 8 | CANNELL CAPITAL LLC | 484,539 | 6,207,000 | 3.02% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 457,511 | 5,861,000 | 2.85% | ||
| 10 | DIMENSIONAL FUND ADVISORS LP | 372,651 | 4,774,000 | 2.32% | ||
| 11 | MILLENNIUM MANAGEMENT LLC | 351,217 | 4,499,000 | 2.19% | ||
| 12 | FULLER & THALER ASSET MANAGEMENT, INC. | 339,941 | 4,355,000 | 2.12% | ||
| 13 | STATE STREET CORP | 327,623 | 4,197,000 | 2.04% | ||
| 14 | OXFORD ASSET MANAGEMENT LLP | 308,255 | 3,949,000 | 1.92% | ||
| 15 | NORTHERN TRUST CORP | 281,122 | 3,602,000 | 1.75% | ||
| 16 | TIVERTON ASSET MANAGEMENT LLC | 275,000 | 3,523,000 | 1.71% | ||
| 17 | DEUTSCHE BANK AG\ | 224,812 | 2,878,000 | 1.40% | ||
| 18 | RENAISSANCE TECHNOLOGIES LLC | 200,600 | 2,570,000 | 1.25% | ||
| 19 | DESTRIER CAPITAL MANAGEMENT LLC | 195,894 | 2,509,000 | 1.22% | ||
| 20 | Simcoe Capital Management, LLC | 165,450 | 2,120,000 | 1.03% | ||
| 21 | Bank of New York Mellon Corp | 162,697 | 2,085,000 | 1.01% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 127,236 | 1,629,000 | 0.79% | ||
| 23 | TFS CAPITAL LLC | 114,494 | 1,467,000 | 0.71% | ||
| 24 | Spark Investment Management LLC | 107,000 | 1,368,000 | 0.66% | ||
| 25 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 104,845 | 1,343,000 | 0.65% | ||
| 26 | PRINCIPAL FINANCIAL GROUP INC | 104,663 | 1,341,000 | 0.65% | ||
| 27 | CONTINENTAL ADVISORS LLC | 104,488 | 1,338,000 | 0.65% | ||
| 28 | CITADEL ADVISORS LLC | 94,085 | 1,205,000 | 0.59% | ||
| 29 | Granite Investment Partners, LLC | 92,455 | 1,184,000 | 0.58% | ||
| 30 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 90,100 | 1,154,000 | 0.56% | ||
| 31 | AMERIPRISE FINANCIAL INC | 77,178 | 989,000 | 0.48% | ||
| 32 | BlackRock Investment Management, LLC | 68,474 | 877,000 | 0.43% | ||
| 33 | GSA CAPITAL PARTNERS LLP | 61,482 | 788,000 | 0.38% | ||
| 34 | NEW YORK STATE TEACHERS RETIREMENT SYSTEM | 59,525 | 763,000 | 0.37% | ||
| 35 | A.R.T. Advisors, LLC | 55,675 | 713,000 | 0.35% | ||
| 36 | NORGES BANK | 55,000 | 705,000 | 0.34% | ||
| 37 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 49,906 | 639,000 | 0.31% | ||
| 38 | ALGERT GLOBAL LLC | 46,494 | 596,000 | 0.29% | ||
| 39 | Invesco Ltd. | 45,587 | 584,000 | 0.28% | ||
| 40 | Cowen Prime Services LLC | 44,400 | 569,000 | 0.28% | ||
| 41 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 43,039 | 552,000 | 0.27% | ||
| 42 | PDT Partners, LLC | 42,379 | 543,000 | 0.26% | ||
| 43 | Trexquant Investment LP | 41,635 | 533,000 | 0.26% | ||
| 44 | PRUDENTIAL FINANCIAL INC | 37,825 | 485,000 | 0.24% | ||
| 45 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 32,608 | 418,000 | 0.20% | ||
| 46 | GOLDMAN SACHS GROUP INC | 31,576 | 404,000 | 0.20% | ||
| 47 | TIAA CREF INVESTMENT MANAGEMENT LLC | 22,600 | 290,000 | 0.14% | ||
| 48 | NEW YORK STATE COMMON RETIREMENT FUND | 22,300 | 286,000 | 0.14% | ||
| 49 | ELLINGTON MANAGEMENT GROUP LLC | 21,945 | 281,000 | 0.14% | ||
| 50 | RHUMBLINE ADVISERS | 18,904 | 242,000 | 0.12% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
