| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ProQuest Associates IV LLC | 4,780,188 | 423,859,000 | 31.66% | ||
| 2 | Consonance Capital Management LP | 1,406,137 | 124,682,000 | 9.31% | ||
| 3 | JANUS HENDERSON INVESTORS US LLC | 1,228,641 | 108,944,000 | 8.14% | ||
| 4 | JW Asset Management, LLC | 857,679 | 76,050,000 | 5.68% | ||
| 5 | Park West Asset Management LLC | 690,000 | 61,182,000 | 4.57% | ||
| 6 | Ranger Investment Management, L.P. | 408,915 | 36,258,000 | 2.71% | ||
| 7 | Cormorant Asset Management, LP | 400,000 | 35,468,000 | 2.65% | ||
| 8 | BlackRock Fund Advisors | 393,097 | 34,856,000 | 2.60% | ||
| 9 | STATE STREET CORP | 383,231 | 33,983,000 | 2.54% | ||
| 10 | VANGUARD GROUP INC | 358,673 | 31,803,000 | 2.38% | ||
| 11 | GENERAL ELECTRIC CO | 336,992 | 29,881,000 | 2.23% | ||
| 12 | Allianz Asset Management GmbH | 294,771 | 26,148,000 | 1.95% | ||
| 13 | C WorldWide Group Holding A/S | 218,907 | 19,410,000 | 1.45% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 210,789 | 18,691,000 | 1.40% | ||
| 15 | Invesco Ltd. | 166,530 | 14,766,000 | 1.10% | ||
| 16 | CASTLEARK MANAGEMENT LLC | 133,410 | 11,829,000 | 0.88% | ||
| 17 | PERCEPTIVE ADVISORS LLC | 133,145 | 11,806,000 | 0.88% | ||
| 18 | AMERICAN CENTURY COMPANIES INC | 121,520 | 10,775,000 | 0.80% | ||
| 19 | BANK OF MONTREAL /CAN/ | 119,902 | 10,632,000 | 0.79% | ||
| 20 | Asset Management One Co., Ltd. | 98,502 | 8,959,000 | 0.67% | ||
| 21 | NORTHERN TRUST CORP | 98,700 | 8,752,000 | 0.65% | ||
| 22 | Opaleye Management Inc. | 85,000 | 7,537,000 | 0.56% | ||
| 23 | PUTNAM INVESTMENTS LLC | 84,450 | 7,488,000 | 0.56% | ||
| 24 | QS Investors, LLC | 76,298 | 6,765,000 | 0.51% | ||
| 25 | RUSSELL FRANK CO/ | 71,401 | 6,371,000 | 0.48% | ||
| 26 | GEODE CAPITAL MANAGEMENT, LLC | 69,950 | 6,202,000 | 0.46% | ||
| 27 | OppenheimerFunds, Inc. | 68,840 | 6,104,000 | 0.46% | ||
| 28 | Century Capital Management, LLC | 66,209 | 5,871,000 | 0.44% | ||
| 29 | Bank of New York Mellon Corp | 62,112 | 5,508,000 | 0.41% | ||
| 30 | GAM Holding AG | 58,200 | 5,161,000 | 0.39% | ||
| 31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 52,800 | 4,682,000 | 0.35% | Put | |
| 32 | BLAIR WILLIAM & CO/IL | 49,100 | 4,353,000 | 0.33% | ||
| 33 | Informed Momentum Co LLC | 48,624 | 4,311,000 | 0.32% | ||
| 34 | Nicholas Investment Partners, LP | 48,556 | 4,305,000 | 0.32% | ||
| 35 | MORGAN STANLEY | 47,523 | 4,213,000 | 0.31% | ||
| 36 | FMR LLC | 45,550 | 4,039,000 | 0.30% | ||
| 37 | WADDELL & REED FINANCIAL INC | 44,100 | 3,910,000 | 0.29% | ||
| 38 | VOLORIDGE INVESTMENT MANAGEMENT, LLC | 42,136 | 3,736,000 | 0.28% | ||
| 39 | TWO SIGMA ADVISERS, LP | 36,491 | 3,236,000 | 0.24% | ||
| 40 | WALL STREET ASSOCIATES | 35,200 | 3,121,000 | 0.23% | ||
| 41 | TCW GROUP INC | 34,977 | 3,101,000 | 0.23% | ||
| 42 | PANAGORA ASSET MANAGEMENT INC | 34,601 | 3,068,000 | 0.23% | ||
| 43 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 33,053 | 2,931,000 | 0.22% | ||
| 44 | PRUDENTIAL FINANCIAL INC | 31,870 | 2,826,000 | 0.21% | ||
| 45 | GOLDMAN SACHS GROUP INC | 31,400 | 2,784,000 | 0.21% | Put | |
| 46 | UBS Group AG | 31,105 | 2,758,000 | 0.21% | ||
| 47 | WELLINGTON MANAGEMENT GROUP LLP | 30,617 | 2,715,000 | 0.20% | ||
| 48 | GOLDMAN SACHS GROUP INC | 30,300 | 2,687,000 | 0.20% | Call | |
| 49 | TIAA CREF INVESTMENT MANAGEMENT LLC | 29,927 | 2,654,000 | 0.20% | ||
| 50 | BlackRock Investment Management, LLC | 28,828 | 2,556,000 | 0.19% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
