| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Third Rock Ventures, LLC | 4,927,234 | 93,420,000 | 24.58% | ||
| 2 | FMR LLC | 3,160,941 | 59,931,000 | 15.77% | ||
| 3 | GILDER GAGNON HOWE & CO LLC | 3,067,422 | 58,158,000 | 15.31% | ||
| 4 | WELLINGTON MANAGEMENT GROUP LLP | 2,001,959 | 37,957,000 | 9.99% | ||
| 5 | LORD, ABBETT & CO. LLC | 1,255,150 | 23,798,000 | 6.26% | ||
| 6 | Alphabet Inc. | 1,144,652 | 21,703,000 | 5.71% | ||
| 7 | Bain Capital Public Equity Management, LLC | 895,800 | 16,984,000 | 4.47% | ||
| 8 | VANGUARD GROUP INC | 575,579 | 10,913,000 | 2.87% | ||
| 9 | BlackRock Fund Advisors | 302,751 | 5,740,000 | 1.51% | ||
| 10 | FRED ALGER MANAGEMENT, LLC | 233,605 | 4,429,000 | 1.17% | ||
| 11 | STATE STREET CORP | 172,398 | 3,270,000 | 0.86% | ||
| 12 | BAILLIE GIFFORD & CO | 165,000 | 3,128,000 | 0.82% | ||
| 13 | NORTHERN TRUST CORP | 159,045 | 3,015,000 | 0.79% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 144,009 | 2,730,000 | 0.72% | ||
| 15 | Lamond Capital Partners LLC | 130,053 | 2,466,000 | 0.65% | ||
| 16 | BAMCO INC /NY/ | 110,132 | 2,088,000 | 0.55% | ||
| 17 | TCW GROUP INC | 98,813 | 1,874,000 | 0.49% | ||
| 18 | PRENTISS SMITH & CO INC | 97,172 | 1,842,000 | 0.48% | ||
| 19 | GEODE CAPITAL MANAGEMENT, LLC | 84,388 | 1,599,000 | 0.42% | ||
| 20 | BAKER BROS. ADVISORS LP | 78,162 | 1,482,000 | 0.39% | ||
| 21 | JPMORGAN CHASE & CO | 77,380 | 1,468,000 | 0.39% | ||
| 22 | Bank of New York Mellon Corp | 71,436 | 1,354,000 | 0.36% | ||
| 23 | GROUP ONE TRADING LLC | 71,094 | 1,348,000 | 0.35% | ||
| 24 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 65,900 | 1,249,000 | 0.33% | Put | |
| 25 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 61,776 | 1,171,000 | 0.31% | ||
| 26 | GOLDMAN SACHS GROUP INC | 57,387 | 1,088,000 | 0.29% | ||
| 27 | TIAA CREF INVESTMENT MANAGEMENT LLC | 53,972 | 1,023,000 | 0.27% | ||
| 28 | GOLDMAN SACHS GROUP INC | 50,000 | 948,000 | 0.25% | Call | |
| 29 | GOLDMAN SACHS GROUP INC | 50,000 | 948,000 | 0.25% | Put | |
| 30 | NORGES BANK | 44,863 | 851,000 | 0.22% | ||
| 31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 42,621 | 808,000 | 0.21% | ||
| 32 | BlackRock Investment Management, LLC | 38,703 | 734,000 | 0.19% | ||
| 33 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 35,886 | 681,000 | 0.18% | ||
| 34 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 25,646 | 486,000 | 0.13% | ||
| 35 | OPPENHEIMER & CO INC | 24,959 | 473,000 | 0.12% | ||
| 36 | TEACHERS ADVISORS, LLC | 24,784 | 470,000 | 0.12% | ||
| 37 | PDT Partners, LLC | 23,880 | 453,000 | 0.12% | ||
| 38 | CREDIT SUISSE AG/ | 22,942 | 436,000 | 0.11% | ||
| 39 | Calamos Advisors LLC | 22,545 | 427,000 | 0.11% | ||
| 40 | Jasper Ridge Partners, L.P. | 21,741 | 412,000 | 0.11% | ||
| 41 | Chevy Chase Trust Holdings, LLC | 21,035 | 399,000 | 0.11% | ||
| 42 | MORGAN STANLEY | 20,564 | 389,000 | 0.10% | ||
| 43 | Cannell & Co. | 20,010 | 379,000 | 0.10% | ||
| 44 | ALLIANCEBERNSTEIN L.P. | 18,900 | 358,000 | 0.09% | ||
| 45 | Swiss National Bank | 17,500 | 332,000 | 0.09% | ||
| 46 | CITADEL ADVISORS LLC | 15,860 | 301,000 | 0.08% | ||
| 47 | UNITED SERVICES AUTOMOBILE ASSOCIATION | 14,600 | 277,000 | 0.07% | ||
| 48 | M&T BANK CORP | 14,017 | 266,000 | 0.07% | ||
| 49 | BOLTON LP | 13,700 | 260,000 | 0.07% | ||
| 50 | BOLTON LP | 13,700 | 260,000 | 0.07% | Put |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
