| 1 |
Avoro Capital Advisors LLC |
2,151,437 |
18,051,000 |
13.90% |
|
|
| 2 |
Cormorant Asset Management, LP |
2,095,334 |
17,580,000 |
13.54% |
|
|
| 3 |
Wildcat Capital Management, LLC |
1,711,063 |
14,355,000 |
11.06% |
|
|
| 4 |
VANGUARD GROUP INC |
792,500 |
6,649,000 |
5.12% |
|
|
| 5 |
BlackRock Fund Advisors |
747,156 |
6,269,000 |
4.83% |
|
|
| 6 |
Numeric Investors LLC |
664,921 |
5,579,000 |
4.30% |
|
|
| 7 |
BlackRock Institutional Trust Company, N.A. |
606,641 |
5,090,000 |
3.92% |
|
|
| 8 |
STATE STREET CORP |
424,752 |
3,564,000 |
2.75% |
|
|
| 9 |
BANK OF AMERICA CORP /DE/ |
378,861 |
3,178,000 |
2.45% |
|
|
| 10 |
Aisling Capital LLC |
353,855 |
2,969,000 |
2.29% |
|
|
| 11 |
FRANKLIN RESOURCES INC |
339,400 |
2,848,000 |
2.19% |
|
|
| 12 |
NORTHERN TRUST CORP |
313,607 |
2,631,000 |
2.03% |
|
|
| 13 |
ACUTA CAPITAL PARTNERS, LLC |
300,000 |
2,517,000 |
1.94% |
|
|
| 14 |
BAIRD FINANCIAL GROUP, INC. |
270,225 |
2,267,000 |
1.75% |
|
|
| 15 |
DEUTSCHE BANK AG\ |
242,068 |
2,029,000 |
1.56% |
|
|
| 16 |
C WorldWide Group Holding A/S |
222,981 |
1,871,000 |
1.44% |
|
|
| 17 |
PUTNAM INVESTMENTS LLC |
211,104 |
1,771,000 |
1.36% |
|
|
| 18 |
GEODE CAPITAL MANAGEMENT, LLC |
193,996 |
1,627,000 |
1.25% |
|
|
| 19 |
GOLDMAN SACHS GROUP INC |
181,600 |
1,524,000 |
1.17% |
Call |
|
| 20 |
GOLDMAN SACHS GROUP INC |
180,700 |
1,516,000 |
1.17% |
Put |
|
| 21 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
172,919 |
1,451,000 |
1.12% |
|
|
| 22 |
SABBY MANAGEMENT, LLC |
167,064 |
1,402,000 |
1.08% |
|
|
| 23 |
MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC |
132,322 |
1,110,000 |
0.85% |
|
|
| 24 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
129,400 |
1,086,000 |
0.84% |
Call |
|
| 25 |
AQR CAPITAL MANAGEMENT LLC |
121,831 |
1,022,000 |
0.79% |
|
|
| 26 |
GSA CAPITAL PARTNERS LLP |
112,067 |
940,000 |
0.72% |
|
|
| 27 |
Spark Investment Management LLC |
106,400 |
891,000 |
0.69% |
|
|
| 28 |
BlackRock Investment Management, LLC |
99,400 |
834,000 |
0.64% |
|
|
| 29 |
Convergence Investment Partners, LLC |
99,136 |
832,000 |
0.64% |
|
|
| 30 |
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS |
96,154 |
807,000 |
0.62% |
|
|
| 31 |
Bank of New York Mellon Corp |
93,204 |
782,000 |
0.60% |
|
|
| 32 |
AlpInvest Partners B.V. |
86,540 |
726,000 |
0.56% |
|
|
| 33 |
Allianz Asset Management GmbH |
86,069 |
722,000 |
0.56% |
|
|
| 34 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
85,000 |
713,000 |
0.55% |
|
|
| 35 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
80,649 |
677,000 |
0.52% |
|
|
| 36 |
PNC FINANCIAL SERVICES GROUP, INC. |
76,661 |
643,000 |
0.50% |
|
|
| 37 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
62,600 |
525,000 |
0.40% |
Put |
|
| 38 |
Granite Investment Partners, LLC |
61,725 |
517,000 |
0.40% |
|
|
| 39 |
MILLENNIUM MANAGEMENT LLC |
58,627 |
492,000 |
0.38% |
|
|
| 40 |
TFS CAPITAL LLC |
54,323 |
456,000 |
0.35% |
|
|
| 41 |
HAMILTON LANE ADVISORS LLC |
51,582 |
433,000 |
0.33% |
|
|
| 42 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
51,609 |
433,000 |
0.33% |
|
|
| 43 |
Spot Trading L.L.C |
50,000 |
420,000 |
0.32% |
Put |
|
| 44 |
Healthcare Value Capital, LLC |
50,000 |
420,000 |
0.32% |
|
|
| 45 |
D. E. Shaw & Co., Inc. |
48,972 |
411,000 |
0.32% |
|
|
| 46 |
Spot Trading L.L.C |
41,662 |
350,000 |
0.27% |
|
|
| 47 |
TEACHERS ADVISORS, LLC |
41,484 |
348,000 |
0.27% |
|
|
| 48 |
FMR LLC |
41,130 |
345,000 |
0.27% |
|
|
| 49 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
39,855 |
335,000 |
0.26% |
|
|
| 50 |
Spot Trading L.L.C |
35,800 |
300,000 |
0.23% |
Call |
|
