| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ALKERMES PLC SHS | 700,000 | 45,038,000 | 5.99% | ||
| 2 | HERON THERAPEUTICS INC | 1,440,000 | 44,870,000 | 5.97% | ||
| 3 | Receptos Inc | 220,000 | 41,811,000 | 5.56% | ||
| 4 | ALDER BIOPHARMACEUTICALS INC | 757,475 | 40,123,000 | 5.33% | ||
| 5 | DYAX CORP COM CVR | 1,400,000 | 37,100,000 | 4.93% | ||
| 6 | NEUROCRINE BIOSCIE COM USD0.001 | 718,900 | 34,335,000 | 4.56% | ||
| 7 | SORRENTO THERAPEUTICS INC COM NEW | 1,945,334 | 34,277,000 | 4.56% | ||
| 8 | EAGLE PHARMACEUTICALS INC COM | 300,000 | 24,258,000 | 3.23% | ||
| 9 | ARDELYX INC COM | 1,481,075 | 23,653,000 | 3.14% | ||
| 10 | PORTOLA PHARMACEUTICALS INC | 500,000 | 22,775,000 | 3.03% | ||
| 11 | NOVAVAX INC COM | 1,600,000 | 17,824,000 | 2.37% | ||
| 12 | TESARO INC | 291,250 | 17,123,000 | 2.28% | ||
| 13 | ALNYLAM PHARMACEUTICALS INC | 140,000 | 16,782,000 | 2.23% | ||
| 14 | QUOTIENT LTD | 1,119,100 | 16,551,000 | 2.20% | ||
| 15 | COHERUS BIOSCIENCES INC COM | 569,130 | 16,448,000 | 2.19% | ||
| 16 | ADVAXIS INC COM NEW | 800,000 | 16,264,000 | 2.16% | ||
| 17 | AGENUS INC | 1,559,000 | 13,454,000 | 1.79% | ||
| 18 | CHINA BIOLOGIC PRODS INC | 111,500 | 12,840,000 | 1.71% | ||
| 19 | DEXCOM | 153,000 | 12,237,000 | 1.63% | ||
| 20 | PFENEX INC COM | 624,900 | 12,123,000 | 1.61% | ||
| 21 | DYNAVAX TECHNOLOGIES CORP | 500,000 | 11,713,000 | 1.56% | ||
| 22 | NEVRO CORP | 208,500 | 11,207,000 | 1.49% | ||
| 23 | ULTRAGENYX PHARMACEUTICAL INC COM | 102,000 | 10,444,000 | 1.39% | ||
| 24 | BIOCRYST PHARMACEUTICALS | 680,000 | 10,152,000 | 1.35% | ||
| 25 | SOCIETAL CDMO INC | 780,000 | 10,078,000 | 1.34% | ||
| 26 | REGULUS THERAPEUTICS INC | 896,522 | 9,826,000 | 1.31% | ||
| 27 | FORWARD PHARMA A/S | 255,000 | 9,703,000 | 1.29% | ||
| 28 | Curis, Inc | 2,632,000 | 8,712,000 | 1.16% | ||
| 29 | KERYX BIOPHARMACEUTICALS INCORPORATED | 826,000 | 8,243,000 | 1.10% | ||
| 30 | KARYOPHARM THERAPEUTICS INC COM | 300,987 | 8,190,000 | 1.09% | ||
| 31 | COLLEGIUM PHARMACEUTICAL INC COM | 450,000 | 8,028,000 | 1.07% | ||
| 32 | OVASCIENCE INC COM | 252,180 | 7,296,000 | 0.97% | ||
| 33 | OMEROS CORP | 388,500 | 6,989,000 | 0.93% | ||
| 34 | MINERVA NEUROSCIENCES INC COM | 1,145,053 | 6,641,000 | 0.88% | ||
| 35 | EPIZYME INC COM | 266,250 | 6,390,000 | 0.85% | ||
| 36 | ACCELERON PHARMA | 200,000 | 6,328,000 | 0.84% | ||
| 37 | ARRAY BIOPHARMA INC COM | 850,000 | 6,129,000 | 0.81% | ||
| 38 | LIPOCINE INC NEW | 666,666 | 5,720,000 | 0.76% | ||
| 39 | Aptose Biosciences Inc Com New | 1,081,867 | 5,542,000 | 0.74% | ||
| 40 | ROCKWELL MED INC COM | 340,000 | 5,481,000 | 0.73% | ||
| 41 | EPIRUS BIOPHARMA | 896,600 | 5,120,000 | 0.68% | ||
| 42 | NEKTAR THERAPEUTICS COM | 397,500 | 4,973,000 | 0.66% | ||
| 43 | Lion Biotechnologies | 499,815 | 4,583,000 | 0.61% | ||
| 44 | KITE PHARMA INCORPORATED | 68,800 | 4,195,000 | 0.56% | ||
| 45 | SANGAMO BIOSCIENCES INCORPORATED | 361,000 | 4,003,000 | 0.53% | ||
| 46 | IMMUNE DESIGN CORP COM | 189,000 | 3,903,000 | 0.52% | ||
| 47 | CELYAD SA | 75,000 | 3,902,000 | 0.52% | ||
| 48 | GLYCOMIMETICS INC | 458,955 | 3,649,000 | 0.49% | ||
| 49 | ACELRX PHARMACEUTICALS INC | 850,000 | 3,604,000 | 0.48% | ||
| 50 | Dicerna Pharmaceuticals | 245,000 | 3,418,000 | 0.45% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001140361-15-032295, filed 2015.08.14).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
