| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Capital Research Global Investors | 2,048,820 | 165,647,000 | 22.79% | ||
| 2 | PRUDENTIAL PLC | 836,124 | 67,601,000 | 9.30% | ||
| 3 | FEDERATED HERMES, INC. | 587,808 | 47,524,000 | 6.54% | ||
| 4 | FMR LLC | 537,927 | 43,492,000 | 5.98% | ||
| 5 | ALLIANCEBERNSTEIN L.P. | 471,134 | 38,091,000 | 5.24% | ||
| 6 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 426,400 | 34,474,000 | 4.74% | Put | |
| 7 | JANUS HENDERSON INVESTORS US LLC | 363,082 | 29,355,000 | 4.04% | ||
| 8 | CHESAPEAKE PARTNERS MANAGEMENT CO INC/MD | 354,278 | 28,643,000 | 3.94% | ||
| 9 | WELLS FARGO & COMPANY/MN | 331,027 | 26,763,000 | 3.68% | ||
| 10 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 330,200 | 26,697,000 | 3.67% | Call | |
| 11 | VHCP Management, LLC | 311,853 | 25,213,000 | 3.47% | ||
| 12 | FARALLON CAPITAL MANAGEMENT LLC | 244,000 | 19,727,000 | 2.71% | ||
| 13 | FRANKLIN RESOURCES INC | 232,770 | 18,819,000 | 2.59% | ||
| 14 | MORGAN STANLEY | 231,424 | 18,711,000 | 2.57% | ||
| 15 | ORBIMED ADVISORS LLC | 221,000 | 17,868,000 | 2.46% | ||
| 16 | CLOUGH CAPITAL PARTNERS L P | 192,600 | 15,572,000 | 2.14% | ||
| 17 | BANK OF AMERICA CORP /DE/ | 145,425 | 11,757,000 | 1.62% | ||
| 18 | CHESAPEAKE PARTNERS MANAGEMENT CO INC/MD | 105,200 | 8,505,000 | 1.17% | Put | |
| 19 | Cupps Capital Management, LLC | 100,213 | 8,102,000 | 1.11% | ||
| 20 | Visium Asset Management, LP | 99,144 | 8,016,000 | 1.10% | ||
| 21 | DRIEHAUS CAPITAL MANAGEMENT LLC | 70,396 | 5,692,000 | 0.78% | ||
| 22 | Fiera Capital Corp | 64,100 | 5,182,000 | 0.71% | ||
| 23 | JANE STREET GROUP, LLC | 54,676 | 4,635,000 | 0.64% | ||
| 24 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 55,398 | 4,479,000 | 0.62% | ||
| 25 | Asset Management One Co., Ltd. | 48,937 | 4,193,000 | 0.58% | ||
| 26 | Iguana Healthcare Management, LLC | 50,000 | 4,043,000 | 0.56% | ||
| 27 | MANAGED ACCOUNT ADVISORS LLC | 41,941 | 3,391,000 | 0.47% | ||
| 28 | Ghost Tree Capital, LLC | 35,000 | 2,830,000 | 0.39% | ||
| 29 | A.R.T. Advisors, LLC | 30,207 | 2,442,000 | 0.34% | ||
| 30 | CITADEL ADVISORS LLC | 26,014 | 2,103,000 | 0.29% | ||
| 31 | Nationwide Fund Advisors | 25,300 | 2,046,000 | 0.28% | ||
| 32 | BALYASNY ASSET MANAGEMENT L.P. | 25,000 | 2,021,000 | 0.28% | Call | |
| 33 | EVENTIDE ASSET MANAGEMENT, LLC | 25,000 | 2,021,000 | 0.28% | ||
| 34 | SABBY MANAGEMENT, LLC | 250 | 2,021,000 | 0.28% | Call | |
| 35 | MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 20,937 | 1,693,000 | 0.23% | ||
| 36 | D. E. Shaw & Co., Inc. | 17,100 | 1,383,000 | 0.19% | Put | |
| 37 | MILLENNIUM MANAGEMENT LLC | 15,200 | 1,229,000 | 0.17% | ||
| 38 | D. E. Shaw & Co., Inc. | 14,799 | 1,196,000 | 0.16% | ||
| 39 | GROUP ONE TRADING LLC | 14,485 | 1,171,000 | 0.16% | ||
| 40 | GARDNER LEWIS ASSET MANAGEMENT L P | 13,700 | 1,108,000 | 0.15% | ||
| 41 | MOORE CAPITAL MANAGEMENT, LP | 13,500 | 1,091,000 | 0.15% | ||
| 42 | ROYAL BANK OF CANADA | 10,500 | 849,000 | 0.12% | ||
| 43 | Bank of New York Mellon Corp | 9,610 | 777,000 | 0.11% | ||
| 44 | Commonwealth Equity Services, Inc | 8,644 | 699,000 | 0.10% | ||
| 45 | UBS AG | 7,000 | 566,000 | 0.08% | Call | |
| 46 | Informed Momentum Co LLC | 6,058 | 490,000 | 0.07% | ||
| 47 | UBS AG | 5,900 | 477,000 | 0.07% | Put | |
| 48 | CREDIT SUISSE AG/ | 5,676 | 459,000 | 0.06% | ||
| 49 | Prospera Financial Services Inc | 5,580 | 451,000 | 0.06% | ||
| 50 | Spot Trading L.L.C | 5,000 | 404,000 | 0.06% | Call |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
