| 1 |
Clarus Ventures, LLC |
4,644,705 |
19,322,000 |
73.10% |
|
|
| 2 |
KINGDON CAPITAL MANAGEMENT, L.L.C. |
286,801 |
1,173,000 |
4.44% |
|
|
| 3 |
Pine River Capital Management L.P. |
209,900 |
873,000 |
3.30% |
|
|
| 4 |
SPHERA FUNDS MANAGEMENT LTD. |
194,200 |
808,000 |
3.06% |
|
|
| 5 |
First Washington CORP |
185,250 |
771,000 |
2.92% |
|
|
| 6 |
EMERALD ADVISERS, LLC |
175,000 |
728,000 |
2.75% |
|
|
| 7 |
WELLINGTON MANAGEMENT GROUP LLP |
160,300 |
667,000 |
2.52% |
|
|
| 8 |
First Eagle Investment Management, LLC |
114,456 |
476,000 |
1.80% |
|
|
| 9 |
Alyeska Investment Group, L.P. |
79,196 |
329,000 |
1.24% |
|
|
| 10 |
HighTower Advisors, LLC |
66,514 |
277,000 |
1.05% |
|
|
| 11 |
MORGAN STANLEY |
54,513 |
227,000 |
0.86% |
|
|
| 12 |
GOLDMAN SACHS GROUP INC |
47,663 |
198,000 |
0.75% |
|
|
| 13 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
35,900 |
149,000 |
0.56% |
|
|
| 14 |
GEODE CAPITAL MANAGEMENT, LLC |
32,274 |
134,000 |
0.51% |
|
|
| 15 |
DEUTSCHE BANK AG\ |
14,142 |
58,000 |
0.22% |
|
|
| 16 |
VANGUARD GROUP INC |
14,018 |
58,000 |
0.22% |
|
|
| 17 |
OPPENHEIMER & CO INC |
11,500 |
48,000 |
0.18% |
|
|
| 18 |
Timber Hill LLC |
10,985 |
46,000 |
0.17% |
|
|
| 19 |
NORTHERN TRUST CORP |
10,554 |
44,000 |
0.17% |
|
|
| 20 |
UBS AG |
4,056 |
17,000 |
0.06% |
|
|
| 21 |
GLENMEDE TRUST CO NA |
3,925 |
16,000 |
0.06% |
|
|
| 22 |
Tower Research Capital LLC (TRC) |
1,441 |
6,000 |
0.02% |
|
|
| 23 |
CITIGROUP INC |
854 |
4,000 |
0.02% |
|
|
| 24 |
BlackRock Investment Management, LLC |
668 |
3,000 |
0.01% |
|
|
| 25 |
BNP PARIBAS FINANCIAL MARKETS |
214 |
890 |
0.00% |
|
|
