| 1 |
Clarus Ventures, LLC |
4,644,705 |
22,387,000 |
73.17% |
|
|
| 2 |
KINGDON CAPITAL MANAGEMENT, L.L.C. |
286,801 |
1,382,000 |
4.52% |
|
|
| 3 |
First Washington CORP |
185,250 |
893,000 |
2.92% |
|
|
| 4 |
EMERALD ADVISERS, LLC |
163,540 |
788,000 |
2.58% |
|
|
| 5 |
WELLINGTON MANAGEMENT GROUP LLP |
145,360 |
701,000 |
2.29% |
|
|
| 6 |
First Eagle Investment Management, LLC |
114,456 |
552,000 |
1.80% |
|
|
| 7 |
VANGUARD GROUP INC |
100,699 |
485,000 |
1.59% |
|
|
| 8 |
Point72 Asset Management, L.P. |
99,470 |
479,000 |
1.57% |
|
|
| 9 |
PURA VIDA INVESTMENTS, LLC |
80,500 |
388,000 |
1.27% |
|
|
| 10 |
Alyeska Investment Group, L.P. |
76,368 |
368,000 |
1.20% |
|
|
| 11 |
Catalyst Capital Advisors LLC |
70,000 |
337,000 |
1.10% |
|
|
| 12 |
HighTower Advisors, LLC |
61,514 |
296,000 |
0.97% |
|
|
| 13 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
35,900 |
205,000 |
0.67% |
|
|
| 14 |
GOLDMAN SACHS GROUP INC |
40,965 |
197,000 |
0.64% |
|
|
| 15 |
MORGAN STANLEY |
39,661 |
191,000 |
0.62% |
|
|
| 16 |
TOCQUEVILLE ASSET MANAGEMENT L.P. |
35,500 |
171,000 |
0.56% |
|
|
| 17 |
GEODE CAPITAL MANAGEMENT, LLC |
32,529 |
156,000 |
0.51% |
|
|
| 18 |
Nicholas Investment Partners, LP |
19,188 |
92,000 |
0.30% |
|
|
| 19 |
DEUTSCHE BANK AG\ |
17,140 |
82,000 |
0.27% |
|
|
| 20 |
Spark Investment Management LLC |
15,500 |
74,000 |
0.24% |
|
|
| 21 |
UBS Group AG |
14,236 |
69,000 |
0.23% |
|
|
| 22 |
MYCIO WEALTH PARTNERS, LLC |
12,000 |
58,000 |
0.19% |
|
|
| 23 |
Virtu KCG Holdings LLC |
10,774 |
52,000 |
0.17% |
|
|
| 24 |
NORTHERN TRUST CORP |
10,554 |
51,000 |
0.17% |
|
|
| 25 |
Bank of New York Mellon Corp |
10,000 |
48,000 |
0.16% |
|
|
| 26 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
10,050 |
48,000 |
0.16% |
|
|
| 27 |
GLENMEDE TRUST CO NA |
3,925 |
18,000 |
0.06% |
|
|
| 28 |
Burt Wealth Advisors |
2,625 |
13,000 |
0.04% |
|
|
| 29 |
Tower Research Capital LLC (TRC) |
1,816 |
8,000 |
0.03% |
|
|
| 30 |
WELLS FARGO & COMPANY/MN |
1,000 |
5,000 |
0.02% |
|
|
| 31 |
BlackRock Investment Management, LLC |
668 |
3,000 |
0.01% |
|
|
