| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Artal Group S.A. | 8,192,167 | 1,966,000 | 60.60% | ||
| 2 | WARBURG PINCUS LLC | 2,460,807 | 591,000 | 18.22% | ||
| 3 | VANGUARD GROUP INC | 855,777 | 205,000 | 6.32% | ||
| 4 | Anson Funds Management LP | 713,514 | 171,000 | 5.27% | ||
| 5 | RENAISSANCE TECHNOLOGIES LLC | 473,593 | 114,000 | 3.51% | ||
| 6 | SABBY MANAGEMENT, LLC | 222,600 | 53,000 | 1.63% | ||
| 7 | Virtu KCG Holdings LLC | 163,299 | 39,000 | 1.20% | ||
| 8 | GABELLI FUNDS LLC | 140,000 | 34,000 | 1.05% | ||
| 9 | CITADEL ADVISORS LLC | 59,346 | 14,000 | 0.43% | ||
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 49,995 | 12,000 | 0.37% | ||
| 11 | CREDIT SUISSE AG/ | 43,954 | 11,000 | 0.34% | ||
| 12 | KBC Group NV | 34,795 | 8,000 | 0.25% | ||
| 13 | Ulys, L.L.C. | 31,131 | 7,000 | 0.22% | ||
| 14 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 15,203 | 4,000 | 0.12% | ||
| 15 | NORTHERN TRUST CORP | 18,150 | 4,000 | 0.12% | ||
| 16 | COBIZ WEALTH, LLC | 10,666 | 3,000 | 0.09% | ||
| 17 | HSBC HOLDINGS PLC | 14,024 | 3,000 | 0.09% | ||
| 18 | GOFEN & GLOSSBERG LLC /IL/ | 10,000 | 2,000 | 0.06% | ||
| 19 | DEUTSCHE BANK AG\ | 10,600 | 2,000 | 0.06% | ||
| 20 | MORGAN STANLEY | 5,200 | 1,000 | 0.03% | ||
| 21 | D.A. DAVIDSON & CO. | 1,000 | 0 | 0.00% | ||
| 22 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 769 | 0 | 0.00% | ||
| 23 | Creative Planning | 2,000 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
