| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Artal Group S.A. | 8,192,167 | 2,703,000 | 65.70% | ||
| 2 | WARBURG PINCUS LLC | 307,600 | 812,000 | 19.74% | ||
| 3 | VANGUARD GROUP INC | 855,777 | 282,000 | 6.85% | ||
| 4 | RENAISSANCE TECHNOLOGIES LLC | 629,100 | 208,000 | 5.06% | ||
| 5 | GABELLI FUNDS LLC | 125,000 | 41,000 | 1.00% | ||
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 50,163 | 16,000 | 0.39% | ||
| 7 | KBC Group NV | 34,795 | 11,000 | 0.27% | ||
| 8 | CITADEL ADVISORS LLC | 29,623 | 10,000 | 0.24% | ||
| 9 | Ulys, L.L.C. | 31,131 | 10,000 | 0.24% | ||
| 10 | NORTHERN TRUST CORP | 18,150 | 6,000 | 0.15% | ||
| 11 | BUCKINGHAM STRATEGIC WEALTH, LLC | 15,000 | 5,000 | 0.12% | ||
| 12 | HSBC HOLDINGS PLC | 14,024 | 5,000 | 0.12% | ||
| 13 | GOFEN & GLOSSBERG LLC /IL/ | 10,000 | 3,000 | 0.07% | ||
| 14 | MORGAN STANLEY | 5,000 | 2,000 | 0.05% | ||
| 15 | D.A. DAVIDSON & CO. | 1,000 | 0 | 0.00% | ||
| 16 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 769 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
