| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 10,492,140 | 100,725,000 | 12.09% | ||
| 2 | PRIMECAP MANAGEMENT CO/CA/ | 8,785,500 | 84,341,000 | 10.13% | ||
| 3 | KORNITZER CAPITAL MANAGEMENT INC /KS | 5,176,450 | 49,694,000 | 5.97% | ||
| 4 | VANGUARD GROUP INC | 4,543,680 | 43,620,000 | 5.24% | ||
| 5 | ORACLE INVESTMENT MANAGEMENT INC | 3,240,006 | 31,104,058 | 3.73% | ||
| 6 | BRIDGER MANAGEMENT, LLC | 3,000,000 | 28,800,000 | 3.46% | ||
| 7 | Boston Partners | 2,543,680 | 24,419,000 | 2.93% | ||
| 8 | Lapides Asset Management, LLC | 2,339,600 | 22,460,000 | 2.70% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 2,316,969 | 22,243,000 | 2.67% | ||
| 10 | BlackRock Fund Advisors | 2,235,779 | 21,463,000 | 2.58% | ||
| 11 | COLUMBIA PARTNERS L.L.C. INVESTMENT MANAGEMENT | 2,175,060 | 20,880,000 | 2.51% | ||
| 12 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,761,569 | 16,911,000 | 2.03% | ||
| 13 | GOLDMAN SACHS GROUP INC | 1,701,600 | 16,335,000 | 1.96% | Put | |
| 14 | GOLDMAN SACHS GROUP INC | 1,645,200 | 15,794,000 | 1.90% | Call | |
| 15 | ROYCE & ASSOCIATES LP | 1,560,000 | 14,976,000 | 1.80% | ||
| 16 | DIMENSIONAL FUND ADVISORS LP | 1,543,607 | 14,817,000 | 1.78% | ||
| 17 | HEARTLAND ADVISORS INC | 1,500,000 | 14,400,000 | 1.73% | ||
| 18 | Redmile Group, LLC | 1,475,360 | 14,163,000 | 1.70% | ||
| 19 | Visium Asset Management, LP | 1,450,000 | 13,920,000 | 1.67% | ||
| 20 | STATE STREET CORP | 1,310,426 | 12,578,000 | 1.51% | ||
| 21 | EAGLE ASSET MANAGEMENT INC | 1,156,565 | 11,103,000 | 1.33% | ||
| 22 | KENNEDY CAPITAL MANAGEMENT LLC | 1,149,474 | 11,035,000 | 1.32% | ||
| 23 | MILLENNIUM MANAGEMENT LLC | 1,122,664 | 10,778,000 | 1.29% | ||
| 24 | DECADE CAPITAL MANAGEMENT LLC | 1,060,000 | 10,176,000 | 1.22% | ||
| 25 | ArrowMark Colorado Holdings LLC | 1,056,600 | 10,143,000 | 1.22% | ||
| 26 | APG Asset Management N.V. | 1,050,000 | 10,080,000 | 1.21% | ||
| 27 | GOLDMAN SACHS GROUP INC | 998,501 | 9,586,000 | 1.15% | ||
| 28 | NORTHERN TRUST CORP | 973,298 | 9,344,000 | 1.12% | ||
| 29 | WELLS FARGO & COMPANY/MN | 871,638 | 8,367,000 | 1.00% | ||
| 30 | SAC Capital Advisors LP | 814,200 | 7,816,000 | 0.94% | ||
| 31 | THB ASSET MANAGEMENT | 793,730 | 7,619,000 | 0.91% | ||
| 32 | Phocas Financial Corp. | 765,030 | 7,344,000 | 0.88% | SH | |
| 33 | Neuberger Berman Group LLC | 754,877 | 7,246,000 | 0.87% | ||
| 34 | Tekla Capital Management LLC | 731,943 | 7,027,000 | 0.84% | ||
| 35 | WHV Investments, Inc. | 714,268 | 6,857,000 | 0.82% | ||
| 36 | March Altus Capital Management LP | 686,569 | 6,591,000 | 0.79% | ||
| 37 | NORGES BANK | 660,607 | 6,342,000 | 0.76% | ||
| 38 | FULLER & THALER ASSET MANAGEMENT, INC. | 517,000 | 4,963,000 | 0.60% | ||
| 39 | NORTH TIDE CAPITAL, LLC | 500,000 | 4,800,000 | 0.58% | ||
| 40 | SECTORAL ASSET MANAGEMENT INC | 483,739 | 4,644,000 | 0.56% | ||
| 41 | Bank of New York Mellon Corp | 453,597 | 4,355,000 | 0.52% | ||
| 42 | PRICE T ROWE ASSOCIATES INC /MD/ | 436,640 | 4,192,000 | 0.50% | ||
| 43 | Ghost Tree Capital, LLC | 400,018 | 3,840,000 | 0.46% | ||
| 44 | GEODE CAPITAL MANAGEMENT, LLC | 346,009 | 3,321,000 | 0.40% | ||
| 45 | MORGAN STANLEY | 322,150 | 3,092,000 | 0.37% | ||
| 46 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 309,596 | 2,972,000 | 0.36% | ||
| 47 | TIAA CREF INVESTMENT MANAGEMENT LLC | 282,789 | 2,715,000 | 0.33% | ||
| 48 | RUSSELL FRANK CO/ | 270,646 | 2,598,000 | 0.31% | ||
| 49 | SOPHROSYNE CAPITAL LLC | 258,300 | 2,480,000 | 0.30% | ||
| 50 | RENAISSANCE TECHNOLOGIES LLC | 247,640 | 2,377,000 | 0.29% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
