| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PRIMECAP MANAGEMENT CO/CA/ | 8,495,700 | 79,010,000 | 9.99% | ||
| 2 | VANGUARD GROUP INC | 4,924,055 | 45,793,000 | 5.79% | ||
| 3 | KORNITZER CAPITAL MANAGEMENT INC /KS | 4,412,115 | 41,033,000 | 5.19% | ||
| 4 | BRIDGER MANAGEMENT, LLC | 3,903,090 | 36,299,000 | 4.59% | ||
| 5 | FMR LLC | 3,821,400 | 35,539,000 | 4.49% | ||
| 6 | ORACLE INVESTMENT MANAGEMENT INC | 3,366,216 | 31,306,000 | 3.96% | ||
| 7 | JPMORGAN CHASE & CO | 3,290,167 | 30,599,000 | 3.87% | ||
| 8 | WELLINGTON MANAGEMENT GROUP LLP | 2,948,730 | 27,423,000 | 3.47% | ||
| 9 | Boston Partners | 2,672,330 | 24,853,000 | 3.14% | ||
| 10 | CLOUGH CAPITAL PARTNERS L P | 2,506,487 | 23,310,000 | 2.95% | ||
| 11 | CHARTWELL INVESTMENT PARTNERS, LLC | 2,456,458 | 22,845,000 | 2.89% | ||
| 12 | BlackRock Fund Advisors | 2,428,091 | 22,581,000 | 2.86% | ||
| 13 | BlackRock Institutional Trust Company, N.A. | 2,273,975 | 21,148,000 | 2.67% | ||
| 14 | HEARTLAND ADVISORS INC | 2,070,700 | 19,258,000 | 2.44% | ||
| 15 | Neuberger Berman Group LLC | 2,062,666 | 19,183,000 | 2.43% | ||
| 16 | ROYCE & ASSOCIATES LP | 2,046,500 | 19,032,000 | 2.41% | ||
| 17 | Lapides Asset Management, LLC | 1,855,100 | 17,252,000 | 2.18% | ||
| 18 | MILLENNIUM MANAGEMENT LLC | 1,665,060 | 15,485,000 | 1.96% | ||
| 19 | Redmile Group, LLC | 1,515,475 | 14,094,000 | 1.78% | ||
| 20 | BLACKROCK ADVISORS LLC | 1,442,283 | 13,413,000 | 1.70% | ||
| 21 | D. E. Shaw & Co., Inc. | 1,433,015 | 13,327,000 | 1.69% | ||
| 22 | ARDSLEY ADVISORY PARTNERS LP | 1,345,000 | 12,515,000 | 1.58% | ||
| 23 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,339,170 | 12,454,000 | 1.58% | ||
| 24 | STATE STREET CORP | 1,296,031 | 12,055,000 | 1.52% | ||
| 25 | Elk Creek Partners, LLC | 1,170,808 | 10,889,000 | 1.38% | ||
| 26 | WELLS FARGO & COMPANY/MN | 1,130,397 | 10,513,000 | 1.33% | ||
| 27 | Point72 Asset Management, L.P. | 1,123,200 | 10,446,000 | 1.32% | ||
| 28 | NORGES BANK | 1,062,339 | 9,880,000 | 1.25% | ||
| 29 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,061,569 | 9,873,000 | 1.25% | ||
| 30 | KENNEDY CAPITAL MANAGEMENT LLC | 883,311 | 8,215,000 | 1.04% | ||
| 31 | Phocas Financial Corp. | 861,040 | 8,008,000 | 1.01% | SH | |
| 32 | NORTHERN TRUST CORP | 856,489 | 7,965,000 | 1.01% | ||
| 33 | Tekla Capital Management LLC | 731,943 | 6,807,000 | 0.86% | ||
| 34 | HealthCor Management, L.P. | 727,000 | 6,761,000 | 0.86% | ||
| 35 | Broadfin Capital, LLC | 700,000 | 6,510,000 | 0.82% | ||
| 36 | Bank of New York Mellon Corp | 566,963 | 5,273,000 | 0.67% | ||
| 37 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 514,189 | 4,782,000 | 0.60% | ||
| 38 | GEODE CAPITAL MANAGEMENT, LLC | 449,815 | 4,183,000 | 0.53% | ||
| 39 | RENAISSANCE TECHNOLOGIES LLC | 447,700 | 4,164,000 | 0.53% | ||
| 40 | MORGAN STANLEY | 408,023 | 3,794,000 | 0.48% | ||
| 41 | J. Goldman & Co LP | 400,000 | 3,720,000 | 0.47% | ||
| 42 | OXFORD ASSET MANAGEMENT LLP | 366,581 | 3,409,000 | 0.43% | ||
| 43 | EVENTIDE ASSET MANAGEMENT, LLC | 364,600 | 3,391,000 | 0.43% | ||
| 44 | TIAA CREF INVESTMENT MANAGEMENT LLC | 272,562 | 2,535,000 | 0.32% | ||
| 45 | WHV Investments, Inc. | 265,330 | 2,468,000 | 0.31% | ||
| 46 | SECTORAL ASSET MANAGEMENT INC | 227,195 | 2,113,000 | 0.27% | ||
| 47 | BlackRock Investment Management, LLC | 224,563 | 2,088,000 | 0.26% | ||
| 48 | CITADEL ADVISORS LLC | 215,522 | 2,004,000 | 0.25% | ||
| 49 | RUSSELL FRANK CO/ | 196,500 | 1,827,000 | 0.23% | ||
| 50 | PUTNAM INVESTMENTS LLC | 182,206 | 1,694,000 | 0.21% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
