| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PRIMECAP MANAGEMENT CO/CA/ | 8,523,000 | 44,234,000 | 11.04% | ||
| 2 | PFM Health Sciences, LP | 5,780,693 | 30,002,000 | 7.49% | ||
| 3 | VANGUARD GROUP INC | 5,745,080 | 29,817,000 | 7.44% | ||
| 4 | Boston Partners | 4,557,399 | 23,653,000 | 5.91% | ||
| 5 | Neuberger Berman Group LLC | 3,330,140 | 17,283,000 | 4.32% | ||
| 6 | RENAISSANCE TECHNOLOGIES LLC | 3,319,000 | 17,226,000 | 4.30% | ||
| 7 | HEARTLAND ADVISORS INC | 2,975,037 | 15,440,000 | 3.85% | ||
| 8 | PRICE T ROWE ASSOCIATES INC /MD/ | 2,894,077 | 15,020,000 | 3.75% | ||
| 9 | BlackRock Fund Advisors | 2,640,300 | 13,703,000 | 3.42% | ||
| 10 | ORACLE INVESTMENT MANAGEMENT INC | 2,482,718 | 12,885,000 | 3.22% | ||
| 11 | Elk Creek Partners, LLC | 2,299,621 | 11,935,000 | 2.98% | ||
| 12 | WELLS FARGO & COMPANY/MN | 2,183,886 | 11,335,000 | 2.83% | ||
| 13 | Lapides Asset Management, LLC | 2,163,600 | 11,229,000 | 2.80% | ||
| 14 | BlackRock Institutional Trust Company, N.A. | 2,090,045 | 10,847,000 | 2.71% | ||
| 15 | WELLINGTON MANAGEMENT GROUP LLP | 2,025,230 | 10,511,000 | 2.62% | ||
| 16 | ROYCE & ASSOCIATES LP | 1,722,000 | 8,937,000 | 2.23% | ||
| 17 | STATE STREET CORP | 1,444,385 | 7,499,000 | 1.87% | ||
| 18 | KORNITZER CAPITAL MANAGEMENT INC /KS | 1,388,848 | 7,208,000 | 1.80% | ||
| 19 | D. E. Shaw & Co., Inc. | 1,386,969 | 7,199,000 | 1.80% | ||
| 20 | NORGES BANK | 1,362,339 | 7,071,000 | 1.77% | ||
| 21 | EMERALD ACQUISITION LTD. | 1,245,882 | 6,467,000 | 1.61% | ||
| 22 | NORTHERN TRUST CORP | 947,979 | 4,920,000 | 1.23% | ||
| 23 | SECTORAL ASSET MANAGEMENT INC | 825,875 | 4,286,000 | 1.07% | ||
| 24 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 778,418 | 4,040,000 | 1.01% | ||
| 25 | MILLENNIUM MANAGEMENT LLC | 745,804 | 3,871,000 | 0.97% | ||
| 26 | PICTET ASSET MANAGEMENT LTD | 687,218 | 3,745,000 | 0.94% | ||
| 27 | RK Capital Management, LLC | 654,950 | 3,399,000 | 0.85% | ||
| 28 | GEODE CAPITAL MANAGEMENT, LLC | 562,914 | 2,921,000 | 0.73% | ||
| 29 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 561,317 | 2,914,000 | 0.73% | ||
| 30 | Bank of New York Mellon Corp | 549,815 | 2,853,000 | 0.71% | ||
| 31 | KENNEDY CAPITAL MANAGEMENT LLC | 499,880 | 2,594,000 | 0.65% | ||
| 32 | Granahan Investment Management, LLC | 449,000 | 2,330,000 | 0.58% | ||
| 33 | MORGAN STANLEY | 413,119 | 2,144,000 | 0.54% | ||
| 34 | DIMENSIONAL FUND ADVISORS LP | 371,820 | 1,930,000 | 0.48% | ||
| 35 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 329,476 | 1,709,000 | 0.43% | ||
| 36 | Vident Investment Advisory, LLC | 313,033 | 1,625,000 | 0.41% | ||
| 37 | BlackRock Investment Management, LLC | 313,041 | 1,625,000 | 0.41% | ||
| 38 | EVENTIDE ASSET MANAGEMENT, LLC | 306,200 | 1,589,000 | 0.40% | ||
| 39 | TIAA CREF INVESTMENT MANAGEMENT LLC | 250,439 | 1,300,000 | 0.32% | ||
| 40 | MENTA CAPITAL LLC | 248,085 | 1,288,000 | 0.32% | ||
| 41 | Spark Investment Management LLC | 232,800 | 1,208,000 | 0.30% | ||
| 42 | Asset Management One Co., Ltd. | 225,900 | 1,172,000 | 0.29% | ||
| 43 | VOCE CAPITAL MANAGEMENT LLC | 223,838 | 1,162,000 | 0.29% | ||
| 44 | ALAMBIC INVESTMENT MANAGEMENT, L.P. | 216,310 | 1,123,000 | 0.28% | ||
| 45 | JACOBS LEVY EQUITY MANAGEMENT, INC | 214,959 | 1,116,000 | 0.28% | ||
| 46 | CORNERSTONE CAPITAL MANAGEMENT HOLDINGS LLC. | 214,100 | 1,111,000 | 0.28% | ||
| 47 | MACQUARIE GROUP LTD | 208,480 | 1,082,000 | 0.27% | ||
| 48 | TWO SIGMA INVESTMENTS, LP | 204,498 | 1,061,000 | 0.26% | ||
| 49 | BANK OF AMERICA CORP /DE/ | 193,792 | 1,006,000 | 0.25% | ||
| 50 | Piermont Capital Management Inc. | 182,242 | 946,000 | 0.24% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
