| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | RHO CAPITAL PARTNERS INC | 3,568,057 | 65,617,000 | 19.45% | ||
| 2 | BlackRock Finance, Inc. | 1,412,092 | 25,968,000 | 7.70% | ||
| 3 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,000,000 | 18,390,000 | 5.45% | ||
| 4 | VANGUARD GROUP INC | 943,627 | 17,353,000 | 5.14% | ||
| 5 | FMR LLC | 938,776 | 17,264,000 | 5.12% | ||
| 6 | CHESCAPMANAGER LLC | 893,390 | 16,429,000 | 4.87% | ||
| 7 | DISCIPLINED GROWTH INVESTORS INC /MN | 876,550 | 16,120,000 | 4.78% | ||
| 8 | FRANKLIN RESOURCES INC | 592,300 | 10,892,000 | 3.23% | ||
| 9 | STATE STREET CORP | 412,739 | 7,592,000 | 2.25% | ||
| 10 | Opaleye Management Inc. | 385,000 | 7,080,000 | 2.10% | ||
| 11 | JPMORGAN CHASE & CO | 346,724 | 6,376,000 | 1.89% | ||
| 12 | MORGAN STANLEY | 332,606 | 6,117,000 | 1.81% | ||
| 13 | JENNISON ASSOCIATES LLC | 300,000 | 5,517,000 | 1.64% | ||
| 14 | PRICE T ROWE ASSOCIATES INC /MD/ | 291,258 | 5,356,000 | 1.59% | ||
| 15 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 285,530 | 5,250,897 | 1.56% | ||
| 16 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 285,000 | 5,241,000 | 1.55% | Put | |
| 17 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 276,600 | 5,087,000 | 1.51% | Call | |
| 18 | TIAA CREF INVESTMENT MANAGEMENT LLC | 273,824 | 5,036,000 | 1.49% | ||
| 19 | NORTHERN TRUST CORP | 246,517 | 4,533,000 | 1.34% | ||
| 20 | Informed Momentum Co LLC | 224,852 | 4,135,000 | 1.23% | ||
| 21 | C WorldWide Group Holding A/S | 214,584 | 3,946,000 | 1.17% | ||
| 22 | DIMENSIONAL FUND ADVISORS LP | 207,950 | 3,824,000 | 1.13% | ||
| 23 | BALYASNY ASSET MANAGEMENT L.P. | 190,000 | 3,494,000 | 1.04% | Put | |
| 24 | GEODE CAPITAL MANAGEMENT, LLC | 186,106 | 3,422,000 | 1.01% | ||
| 25 | MONASHEE INVESTMENT MANAGEMENT LLC | 150,000 | 2,759,000 | 0.82% | PRN | |
| 26 | Rock Springs Capital Management LP | 150,000 | 2,759,000 | 0.82% | ||
| 27 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 143,444 | 2,638,000 | 0.78% | ||
| 28 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 142,500 | 2,621,000 | 0.78% | ||
| 29 | Bank of New York Mellon Corp | 140,997 | 2,593,000 | 0.77% | ||
| 30 | TIVERTON ASSET MANAGEMENT LLC | 140,626 | 2,586,000 | 0.77% | ||
| 31 | Allianz Asset Management GmbH | 120,634 | 2,218,000 | 0.66% | ||
| 32 | NEXTHERA CAPITAL LP | 120,000 | 2,207,000 | 0.65% | ||
| 33 | STIFEL FINANCIAL CORP | 115,452 | 2,123,000 | 0.63% | ||
| 34 | BOOTHBAY FUND MANAGEMENT, LLC | 104,100 | 1,915,000 | 0.57% | Put | |
| 35 | VOLORIDGE INVESTMENT MANAGEMENT, LLC | 102,840 | 1,891,000 | 0.56% | ||
| 36 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 98,962 | 1,820,000 | 0.54% | ||
| 37 | DAFNA Capital Management LLC | 95,322 | 1,753,000 | 0.52% | ||
| 38 | CITADEL ADVISORS LLC | 83,100 | 1,528,000 | 0.45% | Call | |
| 39 | AMERIPRISE FINANCIAL INC | 80,982 | 1,490,000 | 0.44% | ||
| 40 | NEXTHERA CAPITAL LP | 75,000 | 1,379,000 | 0.41% | Call | |
| 41 | Parallax Volatility Advisers, L.P. | 75,000 | 1,379,000 | 0.41% | Call | |
| 42 | BARCLAYS PLC | 74,302 | 1,366,000 | 0.40% | ||
| 43 | MIZUHO SECURITIES USA LLC | 77,500 | 1,355,000 | 0.40% | ||
| 44 | TUDOR INVESTMENT CORP ET AL | 73,635 | 1,354,000 | 0.40% | ||
| 45 | FEDERATED HERMES, INC. | 60,028 | 1,104,000 | 0.33% | ||
| 46 | CITADEL ADVISORS LLC | 56,000 | 1,030,000 | 0.31% | Put | |
| 47 | SHEPHERD KAPLAN KROCHUK, LLC | 52,937 | 974,000 | 0.29% | ||
| 48 | CITADEL ADVISORS LLC | 50,253 | 924,000 | 0.27% | ||
| 49 | Point72 Asset Management, L.P. | 50,000 | 920,000 | 0.27% | Put | |
| 50 | RUSSELL INVESTMENTS GROUP, LTD. | 49,910 | 918,000 | 0.27% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
