| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | OAK MANAGEMENT CORP | 11,917,744 | 50,889,000 | 22.76% | ||
| 2 | WELLCOME TRUST LTD (THE) as trustee of the WELLCOME TRUST | 6,568,646 | 27,982,000 | 12.52% | ||
| 3 | FMR LLC | 6,002,664 | 25,631,000 | 11.47% | ||
| 4 | MORGAN STANLEY | 3,164,822 | 13,514,000 | 6.05% | ||
| 5 | VANGUARD GROUP INC | 2,439,309 | 10,415,000 | 4.66% | ||
| 6 | WELLINGTON MANAGEMENT GROUP LLP | 1,934,106 | 8,258,000 | 3.69% | ||
| 7 | BAILLIE GIFFORD & CO | 1,794,820 | 7,664,000 | 3.43% | ||
| 8 | PRUDENTIAL PLC | 1,716,123 | 7,328,000 | 3.28% | ||
| 9 | EVENTIDE ASSET MANAGEMENT, LLC | 1,708,600 | 7,296,000 | 3.26% | ||
| 10 | Alyeska Investment Group, L.P. | 1,213,511 | 5,182,000 | 2.32% | ||
| 11 | MAVERICK CAPITAL LTD | 1,144,324 | 4,886,000 | 2.19% | ||
| 12 | GAGNON SECURITIES LLC | 968,936 | 4,137,000 | 1.85% | ||
| 13 | BlackRock Institutional Trust Company, N.A. | 884,156 | 3,775,000 | 1.69% | ||
| 14 | MILLENNIUM MANAGEMENT LLC | 881,856 | 3,766,000 | 1.68% | ||
| 15 | BlackRock Fund Advisors | 851,363 | 3,635,000 | 1.63% | ||
| 16 | Gagnon Advisors, LLC | 733,745 | 3,133,000 | 1.40% | ||
| 17 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 578,982 | 2,472,000 | 1.11% | ||
| 18 | ArrowMark Colorado Holdings LLC | 561,177 | 2,396,000 | 1.07% | ||
| 19 | STATE STREET CORP | 489,981 | 2,091,000 | 0.94% | ||
| 20 | Endurant Capital Management LP | 442,508 | 1,890,000 | 0.85% | ||
| 21 | PUTNAM INVESTMENTS LLC | 396,302 | 1,692,000 | 0.76% | ||
| 22 | NORTHERN TRUST CORP | 376,241 | 1,607,000 | 0.72% | ||
| 23 | D. E. Shaw & Co., Inc. | 333,027 | 1,422,000 | 0.64% | ||
| 24 | CITADEL ADVISORS LLC | 297,054 | 1,268,000 | 0.57% | ||
| 25 | Jefferies Group LLC | 261,325 | 1,116,000 | 0.50% | ||
| 26 | Polar Capital LLP | 261,458 | 1,114,000 | 0.50% | ||
| 27 | EverPoint Asset Management, LLC | 250,000 | 1,068,000 | 0.48% | ||
| 28 | KORNITZER CAPITAL MANAGEMENT INC /KS | 250,000 | 1,067,000 | 0.48% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 245,867 | 1,049,000 | 0.47% | ||
| 30 | DEUTSCHE BANK AG\ | 230,217 | 981,000 | 0.44% | ||
| 31 | Teton Advisors, Inc. | 218,339 | 932,000 | 0.42% | ||
| 32 | OPPENHEIMER & CO INC | 207,115 | 884,000 | 0.40% | ||
| 33 | RENAISSANCE TECHNOLOGIES LLC | 179,742 | 767,000 | 0.34% | ||
| 34 | Bank of New York Mellon Corp | 177,974 | 759,000 | 0.34% | ||
| 35 | ALLEN OPERATIONS LLC | 157,372 | 672,000 | 0.30% | ||
| 36 | PRESCOTT GROUP CAPITAL MANAGEMENT, L.L.C. | 149,400 | 638,000 | 0.29% | ||
| 37 | CONTINENTAL ADVISORS LLC | 134,000 | 572,000 | 0.26% | ||
| 38 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 130,800 | 559,000 | 0.25% | Put | |
| 39 | TIAA CREF INVESTMENT MANAGEMENT LLC | 118,070 | 504,000 | 0.23% | ||
| 40 | WEATHERBIE CAPITAL, LLC | 116,200 | 496,000 | 0.22% | Put | |
| 41 | BlackRock Investment Management, LLC | 115,931 | 495,000 | 0.22% | ||
| 42 | Concourse Capital Management, LLC | 110,000 | 470,000 | 0.21% | Call | |
| 43 | Harvey Partners, LLC | 110,000 | 470,000 | 0.21% | ||
| 44 | SABBY MANAGEMENT, LLC | 106,500 | 455,000 | 0.20% | ||
| 45 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 96,581 | 412,000 | 0.18% | ||
| 46 | STONERIDGE INVESTMENT PARTNERS LLC | 94,812 | 405,000 | 0.18% | ||
| 47 | ALLIANCEBERNSTEIN L.P. | 96,150 | 404,000 | 0.18% | ||
| 48 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 91,467 | 391,000 | 0.17% | ||
| 49 | RAYMOND JAMES & ASSOCIATES | 86,200 | 368,000 | 0.16% | ||
| 50 | UBS Group AG | 64,370 | 275,000 | 0.12% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
