| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | JANUS HENDERSON INVESTORS US LLC | 1,545,633 | 59,940,000 | 10.87% | ||
| 2 | Consonance Capital Management LP | 1,119,917 | 43,430,000 | 7.87% | ||
| 3 | FMR LLC | 1,036,170 | 40,183,000 | 7.29% | ||
| 4 | Empyrean Capital Partners, LP | 868,000 | 33,661,000 | 6.10% | ||
| 5 | MILLENNIUM MANAGEMENT LLC | 772,896 | 29,973,000 | 5.43% | ||
| 6 | ORBIMED ADVISORS LLC | 735,600 | 28,527,000 | 5.17% | ||
| 7 | Point72 Asset Management, L.P. | 675,765 | 26,206,000 | 4.75% | ||
| 8 | BlackRock Fund Advisors | 660,160 | 25,601,000 | 4.64% | ||
| 9 | VANGUARD GROUP INC | 646,452 | 25,070,000 | 4.55% | ||
| 10 | BLOOM TREE PARTNERS, LLC | 535,000 | 20,747,000 | 3.76% | ||
| 11 | EverPoint Asset Management, LLC | 475,000 | 18,421,000 | 3.34% | ||
| 12 | BlackRock Institutional Trust Company, N.A. | 361,002 | 14,000,000 | 2.54% | ||
| 13 | Invesco Ltd. | 330,411 | 12,813,000 | 2.32% | ||
| 14 | TIGER GLOBAL MANAGEMENT LLC | 300,000 | 11,634,000 | 2.11% | ||
| 15 | DIMENSIONAL FUND ADVISORS LP | 277,700 | 10,769,000 | 1.95% | ||
| 16 | Foundation Asset Management, LP | 235,195 | 9,121,000 | 1.65% | ||
| 17 | Allianz Asset Management GmbH | 193,153 | 7,490,000 | 1.36% | ||
| 18 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 177,200 | 6,872,000 | 1.25% | Put | |
| 19 | Asset Management One Co., Ltd. | 169,316 | 6,654,000 | 1.21% | ||
| 20 | GOLDMAN SACHS GROUP INC | 169,863 | 6,587,000 | 1.19% | ||
| 21 | ROTHSCHILD & CO ASSET MANAGEMENT US INC. | 169,154 | 6,560,000 | 1.19% | ||
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 153,100 | 5,937,000 | 1.08% | Call | |
| 23 | TEACHERS ADVISORS, LLC | 145,065 | 5,626,000 | 1.02% | ||
| 24 | Opaleye Management Inc. | 122,500 | 4,750,550 | 0.86% | ||
| 25 | STATE STREET CORP | 122,486 | 4,750,000 | 0.86% | ||
| 26 | WELLS FARGO & COMPANY/MN | 112,637 | 4,368,000 | 0.79% | ||
| 27 | NORTHERN TRUST CORP | 111,530 | 4,325,000 | 0.78% | ||
| 28 | AMERICAN CENTURY COMPANIES INC | 103,317 | 4,007,000 | 0.73% | ||
| 29 | QS BATTERYMARCH FINANCIAL MANAGEMENT, INC | 102,368 | 3,970,000 | 0.72% | ||
| 30 | GUGGENHEIM CAPITAL LLC | 86,342 | 3,348,000 | 0.61% | ||
| 31 | SYSTEMATIC FINANCIAL MANAGEMENT LP | 82,010 | 3,180,000 | 0.58% | ||
| 32 | CREDIT SUISSE AG/ | 76,172 | 2,954,000 | 0.54% | ||
| 33 | PUTNAM INVESTMENTS LLC | 75,547 | 2,929,000 | 0.53% | ||
| 34 | J. Goldman & Co LP | 74,000 | 2,870,000 | 0.52% | ||
| 35 | NEW YORK STATE COMMON RETIREMENT FUND | 71,400 | 2,769,000 | 0.50% | ||
| 36 | GREEN ARROW CAPITAL MANAGEMENT LLC | 70,000 | 2,715,000 | 0.49% | ||
| 37 | BLACKROCK ADVISORS LLC | 68,927 | 2,673,000 | 0.48% | ||
| 38 | GEODE CAPITAL MANAGEMENT, LLC | 57,407 | 2,225,000 | 0.40% | ||
| 39 | Robert W. Baird & Co. Inc | 53,513 | 2,075,000 | 0.38% | SH | |
| 40 | Bank of New York Mellon Corp | 53,018 | 2,056,000 | 0.37% | ||
| 41 | M&T BANK CORP | 51,634 | 2,002,000 | 0.36% | ||
| 42 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 51,307 | 1,990,000 | 0.36% | ||
| 43 | Atika Capital Management LLC | 51,000 | 1,978,000 | 0.36% | ||
| 44 | MORGAN STANLEY | 47,460 | 1,840,000 | 0.33% | ||
| 45 | A.R.T. Advisors, LLC | 42,757 | 1,658,000 | 0.30% | ||
| 46 | GAM Holding AG | 41,970 | 1,628,000 | 0.30% | ||
| 47 | AQR CAPITAL MANAGEMENT LLC | 39,652 | 1,538,000 | 0.28% | ||
| 48 | TIAA CREF INVESTMENT MANAGEMENT LLC | 36,882 | 1,430,000 | 0.26% | ||
| 49 | ANALYTIC INVESTORS, LLC | 35,257 | 1,367,000 | 0.25% | ||
| 50 | Weiss Multi-Strategy Advisers LLC | 35,000 | 1,357,000 | 0.25% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
