| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 1,535,661 | 21,469,000 | 14.75% | ||
| 2 | Numeric Investors LLC | 694,299 | 9,706,000 | 6.67% | ||
| 3 | JENNISON ASSOCIATES LLC | 684,440 | 9,568,000 | 6.57% | ||
| 4 | PERCEPTIVE ADVISORS LLC | 650,591 | 9,095,000 | 6.25% | ||
| 5 | EMERALD MUTUAL FUND ADVISERS TRUST | 475,788 | 6,652,000 | 4.57% | ||
| 6 | BlackRock Fund Advisors | 462,972 | 6,472,000 | 4.45% | ||
| 7 | PUTNAM INVESTMENTS LLC | 414,907 | 5,801,000 | 3.99% | ||
| 8 | VANGUARD GROUP INC | 414,200 | 5,790,000 | 3.98% | ||
| 9 | EMERALD ADVISERS, LLC | 301,864 | 4,220,000 | 2.90% | ||
| 10 | ACADIAN ASSET MANAGEMENT LLC | 296,464 | 4,145,000 | 2.85% | ||
| 11 | EVENTIDE ASSET MANAGEMENT, LLC | 279,100 | 3,902,000 | 2.68% | ||
| 12 | RA CAPITAL MANAGEMENT, L.P. | 236,059 | 3,300,000 | 2.27% | ||
| 13 | PANAGORA ASSET MANAGEMENT INC | 195,815 | 2,737,000 | 1.88% | ||
| 14 | PRICE T ROWE ASSOCIATES INC /MD/ | 189,981 | 2,656,000 | 1.82% | ||
| 15 | STATE STREET CORP | 175,970 | 2,461,000 | 1.69% | ||
| 16 | TFS CAPITAL LLC | 168,524 | 2,356,000 | 1.62% | ||
| 17 | DAFNA Capital Management LLC | 167,192 | 2,337,000 | 1.61% | ||
| 18 | OXFORD ASSET MANAGEMENT LLP | 166,088 | 2,322,000 | 1.60% | ||
| 19 | JPMORGAN CHASE & CO | 163,589 | 2,287,000 | 1.57% | ||
| 20 | BlackRock Institutional Trust Company, N.A. | 162,328 | 2,269,000 | 1.56% | ||
| 21 | Visium Asset Management, LP | 154,751 | 2,163,000 | 1.49% | ||
| 22 | Invesco Ltd. | 149,275 | 2,087,000 | 1.43% | ||
| 23 | MILLENNIUM MANAGEMENT LLC | 131,148 | 1,833,000 | 1.26% | ||
| 24 | GEODE CAPITAL MANAGEMENT, LLC | 110,367 | 1,542,000 | 1.06% | ||
| 25 | BOGLE INVESTMENT MANAGEMENT L P /DE/ | 103,973 | 1,453,000 | 1.00% | ||
| 26 | C WorldWide Group Holding A/S | 103,500 | 1,447,000 | 0.99% | ||
| 27 | Iguana Healthcare Management, LLC | 100,000 | 1,398,000 | 0.96% | ||
| 28 | Spark Investment Management LLC | 99,900 | 1,396,000 | 0.96% | ||
| 29 | NORTHERN TRUST CORP | 97,248 | 1,360,000 | 0.93% | ||
| 30 | RUSSELL FRANK CO/ | 96,208 | 1,345,000 | 0.92% | ||
| 31 | AMERICAN CENTURY COMPANIES INC | 85,465 | 1,195,000 | 0.82% | ||
| 32 | AQR CAPITAL MANAGEMENT LLC | 82,239 | 1,150,000 | 0.79% | ||
| 33 | CITADEL ADVISORS LLC | 81,657 | 1,142,000 | 0.78% | ||
| 34 | TIAA CREF INVESTMENT MANAGEMENT LLC | 81,415 | 1,138,000 | 0.78% | ||
| 35 | Point72 Asset Management, L.P. | 76,659 | 1,072,000 | 0.74% | ||
| 36 | DEUTSCHE BANK AG\ | 72,663 | 1,014,000 | 0.70% | ||
| 37 | RENAISSANCE TECHNOLOGIES LLC | 71,200 | 995,000 | 0.68% | ||
| 38 | D. E. Shaw & Co., Inc. | 67,744 | 947,000 | 0.65% | ||
| 39 | Allianz Asset Management GmbH | 50,775 | 710,000 | 0.49% | ||
| 40 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 46,450 | 649,000 | 0.45% | ||
| 41 | Bank of New York Mellon Corp | 44,941 | 629,000 | 0.43% | ||
| 42 | Trexquant Investment LP | 41,882 | 586,000 | 0.40% | ||
| 43 | BLACKROCK ADVISORS LLC | 41,010 | 573,000 | 0.39% | ||
| 44 | STRS OHIO | 40,800 | 570,000 | 0.39% | ||
| 45 | MORGAN STANLEY | 40,497 | 567,000 | 0.39% | ||
| 46 | GOLDMAN SACHS GROUP INC | 36,511 | 510,000 | 0.35% | ||
| 47 | BANK OF MONTREAL /CAN/ | 31,904 | 446,000 | 0.31% | ||
| 48 | BlackRock Investment Management, LLC | 30,720 | 429,000 | 0.29% | ||
| 49 | Dynamic Technology Lab Private Ltd | 30,584 | 428,000 | 0.29% | ||
| 50 | A.R.T. Advisors, LLC | 27,560 | 385,000 | 0.26% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
