| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | INTERWEST VENTURE MANAGEMENT CO | 1,452,216 | 13,579,000 | 12.70% | ||
| 2 | FMR LLC | 1,115,494 | 10,430,000 | 9.75% | ||
| 3 | ACADIAN ASSET MANAGEMENT LLC | 716,341 | 6,700,000 | 6.27% | ||
| 4 | Numeric Investors LLC | 566,800 | 5,300,000 | 4.96% | ||
| 5 | VANGUARD GROUP INC | 535,458 | 5,007,000 | 4.68% | ||
| 6 | AJO, LP | 469,644 | 4,391,000 | 4.11% | ||
| 7 | MILLENNIUM MANAGEMENT LLC | 440,638 | 4,120,000 | 3.85% | ||
| 8 | BlackRock Fund Advisors | 411,554 | 3,848,000 | 3.60% | ||
| 9 | EMERALD MUTUAL FUND ADVISERS TRUST | 335,661 | 3,138,000 | 2.93% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 330,313 | 3,088,000 | 2.89% | ||
| 11 | PUTNAM INVESTMENTS LLC | 308,067 | 2,880,000 | 2.69% | ||
| 12 | STATE STREET CORP | 300,983 | 2,813,000 | 2.63% | ||
| 13 | DAFNA Capital Management LLC | 286,298 | 2,677,000 | 2.50% | ||
| 14 | EMERALD ADVISERS, LLC | 283,551 | 2,651,000 | 2.48% | ||
| 15 | EVENTIDE ASSET MANAGEMENT, LLC | 279,100 | 2,610,000 | 2.44% | ||
| 16 | PANAGORA ASSET MANAGEMENT INC | 228,109 | 2,133,000 | 1.99% | ||
| 17 | AQR CAPITAL MANAGEMENT LLC | 213,688 | 1,998,000 | 1.87% | ||
| 18 | PRICE T ROWE ASSOCIATES INC /MD/ | 190,016 | 1,777,000 | 1.66% | ||
| 19 | OXFORD ASSET MANAGEMENT LLP | 185,981 | 1,739,000 | 1.63% | ||
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 146,256 | 1,367,000 | 1.28% | ||
| 21 | NORTHERN TRUST CORP | 133,011 | 1,243,000 | 1.16% | ||
| 22 | MORGAN STANLEY | 132,139 | 1,236,000 | 1.16% | ||
| 23 | PRUDENTIAL FINANCIAL INC | 125,010 | 1,169,000 | 1.09% | ||
| 24 | GLOBEFLEX CAPITAL L P | 124,514 | 1,164,000 | 1.09% | ||
| 25 | AMERICAN CENTURY COMPANIES INC | 116,123 | 1,086,000 | 1.02% | ||
| 26 | GSA CAPITAL PARTNERS LLP | 113,300 | 1,059,000 | 0.99% | ||
| 27 | BLACKROCK ADVISORS LLC | 108,364 | 1,013,000 | 0.95% | ||
| 28 | Walleye Trading LLC | 103,600 | 969,000 | 0.91% | ||
| 29 | TIAA CREF INVESTMENT MANAGEMENT LLC | 97,527 | 912,000 | 0.85% | ||
| 30 | Granite Investment Partners, LLC | 80,120 | 749,000 | 0.70% | ||
| 31 | DEUTSCHE BANK AG\ | 80,184 | 749,000 | 0.70% | ||
| 32 | RUSSELL INVESTMENTS GROUP, LTD. | 75,827 | 747,000 | 0.70% | ||
| 33 | ALGERT GLOBAL LLC | 66,795 | 625,000 | 0.58% | ||
| 34 | STRS OHIO | 65,200 | 609,000 | 0.57% | ||
| 35 | GOLDMAN SACHS GROUP INC | 60,482 | 566,000 | 0.53% | ||
| 36 | Bank of New York Mellon Corp | 55,076 | 515,000 | 0.48% | ||
| 37 | RENAISSANCE TECHNOLOGIES LLC | 52,700 | 493,000 | 0.46% | ||
| 38 | BANK OF AMERICA CORP /DE/ | 50,993 | 476,000 | 0.45% | ||
| 39 | PERCEPTIVE ADVISORS LLC | 50,251 | 470,000 | 0.44% | ||
| 40 | MILLENNIUM MANAGEMENT LLC | 50,000 | 468,000 | 0.44% | Call | |
| 41 | BlackRock Investment Management, LLC | 48,674 | 455,000 | 0.43% | ||
| 42 | DIMENSIONAL FUND ADVISORS LP | 45,653 | 427,000 | 0.40% | ||
| 43 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 45,000 | 421,000 | 0.39% | ||
| 44 | CITADEL ADVISORS LLC | 44,016 | 412,000 | 0.39% | ||
| 45 | Connor, Clark & Lunn Investment Management Ltd. | 40,075 | 375,000 | 0.35% | ||
| 46 | BlackRock Group LTD | 38,703 | 362,000 | 0.34% | ||
| 47 | BANK OF MONTREAL /CAN/ | 39,251 | 360,000 | 0.34% | ||
| 48 | Allianz Asset Management GmbH | 36,875 | 345,000 | 0.32% | ||
| 49 | ClariVest Asset Management LLC | 36,600 | 342,000 | 0.32% | ||
| 50 | DUPONT CAPITAL MANAGEMENT CORP | 36,509 | 341,000 | 0.32% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
