| 1 |
Essex Woodlands Management, Inc. |
9,353,304 |
87,453,000 |
47.69% |
|
|
| 2 |
Broadfin Capital, LLC |
1,802,092 |
16,850,000 |
9.19% |
|
|
| 3 |
GOLDMAN SACHS GROUP INC |
1,346,501 |
12,589,000 |
6.86% |
|
|
| 4 |
Tamarack Capital Management, LLC |
1,325,000 |
12,389,000 |
6.76% |
|
|
| 5 |
SENZAR ASSET MANAGEMENT, LLC |
1,204,721 |
11,264,141 |
6.14% |
|
|
| 6 |
RTW INVESTMENTS, LP |
575,212 |
5,378,000 |
2.93% |
|
|
| 7 |
FRANKLIN RESOURCES INC |
557,490 |
5,213,000 |
2.84% |
|
|
| 8 |
VANGUARD GROUP INC |
342,495 |
3,203,000 |
1.75% |
|
|
| 9 |
PUTNAM INVESTMENTS LLC |
325,000 |
3,039,000 |
1.66% |
|
|
| 10 |
BlackRock Fund Advisors |
269,733 |
2,522,000 |
1.38% |
|
|
| 11 |
WALL STREET ASSOCIATES |
265,700 |
2,484,000 |
1.35% |
|
|
| 12 |
TFS CAPITAL LLC |
192,390 |
1,799,000 |
0.98% |
|
|
| 13 |
EMERALD MUTUAL FUND ADVISERS TRUST |
175,000 |
1,636,000 |
0.89% |
|
|
| 14 |
AWM Investment Company, Inc. |
175,000 |
1,636,000 |
0.89% |
|
|
| 15 |
MARSHALL WACE, LLP |
175,000 |
1,636,000 |
0.89% |
|
|
| 16 |
Lombard Odier Asset Management (USA) Corp |
172,567 |
1,614,000 |
0.88% |
|
|
| 17 |
Ghost Tree Capital, LLC |
125,000 |
1,169,000 |
0.64% |
|
|
| 18 |
BlackRock Institutional Trust Company, N.A. |
114,331 |
1,069,000 |
0.58% |
|
|
| 19 |
NORTHERN TRUST CORP |
106,321 |
994,000 |
0.54% |
|
|
| 20 |
NEEDHAM INVESTMENT MANAGEMENT LLC |
100,108 |
936,000 |
0.51% |
|
|
| 21 |
TURNER INVESTMENTS LLC |
100,000 |
935,000 |
0.51% |
|
|
| 22 |
Informed Momentum Co LLC |
99,340 |
929,000 |
0.51% |
|
|
| 23 |
MILLENNIUM MANAGEMENT LLC |
86,734 |
811,000 |
0.44% |
|
|
| 24 |
GEODE CAPITAL MANAGEMENT, LLC |
75,536 |
706,000 |
0.38% |
|
|
| 25 |
STATE STREET CORP |
73,350 |
686,000 |
0.37% |
|
|
| 26 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
70,000 |
655,000 |
0.36% |
|
|
| 27 |
GLG LLC |
70,000 |
654,000 |
0.36% |
|
|
| 28 |
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
65,000 |
608,000 |
0.33% |
|
|
| 29 |
Spark Investment Management LLC |
37,000 |
345,000 |
0.19% |
|
|
| 30 |
BlackRock Investment Management, LLC |
36,919 |
345,000 |
0.19% |
|
|
| 31 |
Bank of New York Mellon Corp |
35,719 |
334,000 |
0.18% |
|
|
| 32 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
22,982 |
215,000 |
0.12% |
|
|
| 33 |
APIS CAPITAL ADVISORS, LLC |
22,000 |
206,000 |
0.11% |
|
|
| 34 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
19,371 |
181,000 |
0.10% |
|
|
| 35 |
TEACHERS ADVISORS, LLC |
12,997 |
122,000 |
0.07% |
|
|
| 36 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
12,013 |
113,000 |
0.06% |
|
|
| 37 |
CORNERSTONE CAPITAL MANAGEMENT HOLDINGS LLC. |
11,800 |
110,000 |
0.06% |
|
|
| 38 |
PANAGORA ASSET MANAGEMENT INC |
8,540 |
80,000 |
0.04% |
|
|
| 39 |
NEW YORK STATE COMMON RETIREMENT FUND |
8,000 |
75,000 |
0.04% |
|
|
| 40 |
PRELUDE CAPITAL MANAGEMENT, LLC |
6,500 |
61,000 |
0.03% |
|
|
| 41 |
Nationwide Fund Advisors |
5,433 |
51,000 |
0.03% |
|
|
| 42 |
AMERICAN INTERNATIONAL GROUP, INC. |
5,098 |
48,000 |
0.03% |
|
|
| 43 |
BLACKROCK ADVISORS LLC |
5,000 |
47,000 |
0.03% |
|
|
| 44 |
MORGAN STANLEY |
4,871 |
46,000 |
0.03% |
|
|
| 45 |
VICTORY CAPITAL MANAGEMENT INC |
2,934 |
27,000 |
0.01% |
|
|
| 46 |
DEUTSCHE BANK AG\ |
2,956 |
27,000 |
0.01% |
|
|
| 47 |
STRS OHIO |
2,800 |
26,000 |
0.01% |
|
|
| 48 |
BNP PARIBAS FINANCIAL MARKETS |
2,174 |
20,327 |
0.01% |
|
|
| 49 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
2,018 |
19,000 |
0.01% |
|
|
| 50 |
Parallax Volatility Advisers, L.P. |
1,783 |
17,000 |
0.01% |
|
|
